Understanding long-term effects of blood clots
Official title: Venous Thromboembolism Sequelae in a Population-based Inception Cohort
Funded at Kaiser Foundation Research Institute · NIH-11098542 · Data updated 2026-11-12
This study is looking at how people who have had a blood clot, like deep vein thrombosis or pulmonary embolism, might feel in the year after their treatment, especially those using newer blood thinners, to better understand their symptoms and help improve their recovery and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | June 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $803,578 |
| NIH project number | 5R01HL166292-03 |
| Project ID | NIH-11098542 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have recently experienced a venous thromboembolism.
✕Less likely to help
Patients who have not experienced a venous thromboembolism or those under 21 years old may not benefit from this research.
What this research studies
This research investigates the long-term consequences that patients may experience after a venous thromboembolism (VTE), which includes conditions like deep vein thrombosis and pulmonary embolism. It focuses on identifying symptoms and adverse outcomes that can occur in the year following the initial event, particularly in patients treated with newer anticoagulants. The study aims to explore the relationship between various biomarkers and lifestyle factors, such as physical activity, and the risk of developing chronic issues after a VTE. By gathering data from a population-based cohort, the research seeks to improve patient care and rehabilitation strategies.
Why it matters
Potential benefit: If successful, this research could lead to better identification and management of patients at risk for long-term complications after a blood clot.
How similar studies have gone: Previous research has shown promising results in understanding post-thrombotic syndrome, but this study's focus on newer anticoagulants and comprehensive symptom tracking is relatively novel.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Harrington, Laura Brienne — Kaiser Foundation Research Institute
- Study coordinator: Harrington, Laura Brienne
Related research
Other NIH-funded projects on the same topics.
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Statins to Prevent Cancer-Associated Blood Clots in Cancer Patients
A large study will test whether taking rosuvastatin every day for a year can lower the chance of dangerous blood clots in people with cancer, without raising the risk of bleeding.
-
Optimal use of blood thinners for venous clots in people with cirrhosis
This grant hopes to figure out the safest and most effective way to use oral anticoagulants for adults with cirrhosis who develop venous clots.
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PET/CT imaging to detect chemotherapy-related vascular harm in young cancer patients
A non-invasive PET/CT scan method using standard care imaging is being tested to identify which pediatric and young adult cancer patients are at higher risk of blood clots from chemotherapy.
-
Statins to Prevent Cancer-Associated Blood Clots in Cancer Patients
A large clinical trial will test whether taking rosuvastatin daily for a year helps prevent dangerous blood clots in people with newly diagnosed or relapsed cancer who aren’t already getting anticoagulants.
-
BCOR's role in blood clot risk and liver genetics
A Johns Hopkins-led study is exploring how a human gene, BCOR, may control liver-produced clotting factors to influence venous blood clots.
-
Personalized risk-prediction for hospital-acquired blood clots in adults
A real-time risk model helps doctors identify adults in the hospital who are at higher risk of developing blood clots so they can prevent them safely.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.