Improving prevention of blood clots in hospitalized patients
Official title: Disseminating a Patient Centered Venous Thromboembolism Prevention Bundle
Funded at Johns Hopkins University · NIH-10794235 · Data updated 2026-11-12
This study is looking at ways to help hospitalized patients remember to take their blood clot prevention medications by using real-time support, so they can stay involved in their care and lower their chances of getting preventable blood clots.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 1, 2020 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $379,952 |
| NIH project number | 5R18HS027415-05 |
| Project ID | NIH-10794235 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are hospitalized patients who are at risk for venous thromboembolism and have been prescribed prophylactic medication.
✕Less likely to help
Patients who are not hospitalized or those who do not require VTE prophylaxis may not benefit from this research.
What this research studies
This research focuses on enhancing the adherence to venous thromboembolism (VTE) prophylaxis among hospitalized patients. It utilizes a patient-centered approach, leveraging electronic health record data to deliver real-time interventions that empower patients to actively participate in their care. By addressing the common issue of medication nonadherence, the study aims to ensure that patients receive the preventive treatments they have been prescribed, ultimately reducing the risk of preventable blood clots during hospitalization.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of preventable blood clots in hospitalized patients, improving overall patient safety and outcomes.
How similar studies have gone: Previous research has shown success in improving medication adherence through patient-centered interventions, indicating a promising approach for this study.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Lau, Brandyn Daniel — Johns Hopkins University
- Study coordinator: Lau, Brandyn Daniel
Related research
Other NIH-funded projects on the same topics.
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-
Optimal use of blood thinners for venous clots in people with cirrhosis
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-
PET/CT imaging to detect chemotherapy-related vascular harm in young cancer patients
A non-invasive PET/CT scan method using standard care imaging is being tested to identify which pediatric and young adult cancer patients are at higher risk of blood clots from chemotherapy.
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Statins to Prevent Cancer-Associated Blood Clots in Cancer Patients
A large clinical trial will test whether taking rosuvastatin daily for a year helps prevent dangerous blood clots in people with newly diagnosed or relapsed cancer who aren’t already getting anticoagulants.
-
BCOR's role in blood clot risk and liver genetics
A Johns Hopkins-led study is exploring how a human gene, BCOR, may control liver-produced clotting factors to influence venous blood clots.
-
Personalized risk-prediction for hospital-acquired blood clots in adults
A real-time risk model helps doctors identify adults in the hospital who are at higher risk of developing blood clots so they can prevent them safely.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.