Personalized risk-prediction for hospital-acquired blood clots in adults
Official title: Optimizing the implementation of personalized risk-prediction models for venous thromboembolism among hospitalized adults
Funded at Vanderbilt University Medical Center · NIH-11373022 · Data updated 2026-11-12
A real-time risk model helps doctors identify adults in the hospital who are at higher risk of developing blood clots so they can prevent them safely.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $645,612 |
| NIH project number | 5R01HL164482-04 |
| Project ID | NIH-11373022 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adult inpatients at participating hospitals who are at risk for venous thromboembolism.
✕Less likely to help
Patients with extremely low baseline risk or those not receiving thromboprophylaxis may see no direct benefit.
What this research studies
This project aims to refine and implement a real-time prognostic tool that updates as a patient’s condition changes, guiding timely thromboprophylaxis to reduce hospital-acquired VTE. The team combines clinical input with data-based predictions to improve accuracy beyond current tools. By focusing on ease of use for busy clinicians, the study seeks to integrate the model into daily practice and evaluate its impact on patient outcomes. The work is conducted at Vanderbilt University Medical Center with a multidisciplinary team to ensure practical applicability in hospital settings.
Why it matters
Potential benefit: If successful, patients could experience fewer hospital-acquired blood clots and related complications through more timely prevention.
How similar studies have gone: Earlier tools struggled with implementation and predictive accuracy, while this project aims to outperform existing models and streamline use at the bedside.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: French, Benjamin — Vanderbilt University Medical Center
- Study coordinator: French, Benjamin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.