Evaluating complications of anticoagulant treatment in cancer patients with blood clots
Official title: Thromboembolic and Hemorrhagic Complications of Anticoagulant Treatment in Patients With CAT (Cancer Associated Thrombosis)
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06714734 · Data updated 2026-11-12
This study looks at how often blood clots and bleeding problems happen in cancer patients who are being treated with blood thinners.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 2 sites (Bologna and 1 other locations) |
| Status | Recruiting |
| Started | January 2, 2016 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | December 4, 2024 |
| Trial ID | NCT06714734 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older with a diagnosis of venous thromboembolism in the context of neoplasia.
✕Probably not a fit
Patients without a diagnosis of venous thromboembolism or those not related to neoplasia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the frequency of thrombotic and hemorrhagic complications in adult patients diagnosed with venous thromboembolism related to neoplasia. It will involve both retrospective and prospective data collection from patients treated at two medical centers in Italy. The study will follow patients according to standard clinical practices and will not alter their diagnostic or therapeutic pathways based on study results. Data analysis is expected to conclude by the end of 2027.
Why it matters
Potential benefit: If successful, this study could improve the understanding of anticoagulant treatment safety in cancer patients, potentially leading to better management strategies.
How similar studies have gone: While this study is observational, similar studies have shown varying degrees of success in understanding anticoagulant complications in cancer patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of venous thrombosis at any site * Diagnosis of CVC-related venous thrombosis * Diagnosis of pulmonary embolism, both symptomatic and incidental * Diagnosis of solid or hematological neoplasm, either under treatment or active * Obtaining of Informed Consent Exclusion Criteria: * None
Where it's running
-
IRCCS Azianda Ospedaliero-Universitaria di Bologna
Bologna, Italy Recruiting -
IRCCS Arcispedale S. Maria Nuova di Reggio Emilia
Reggio Emilia, Italy Recruiting
Study contacts
- Principal investigator: Benilde Cosmi, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Benilde Cosmi, MD
- Email: benilde.cosmi@unibo.it
- Phone: 0512142483
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
DoACs vs LMWH for blood flow after knee replacement
This study tests whether rivaroxaban, apixaban, or LMWH work differently to support blood flow in the legs after total knee replacement in adults.
-
Prognostic value of the 2026 AHA/ACC PE classification in ED patients with acute PE
This study tests whether the 2026 AHA/ACC five-category PE classification helps predict 30-day major adverse pulmonary embolism events in adults with acute PE presenting to the ED.
-
Screening for blood clots in adults with acute heart failure
This trial tests whether a guideline-based screening approach can detect pulmonary embolism in adults admitted with acute heart failure.
-
Blood test and software to guide treatment for venous thromboembolism
This project tests whether a blood-based ctDNA test combined with a software risk score can predict if VTE will come back in adults with cancer-associated DVT or PE who have finished 3–12 months of anticoagulation.
-
Aspiration thrombectomy with the Symphony or Prodigy devices
This project will try the Symphony and Prodigy aspiration thrombectomy devices to remove arterial, venous, or pulmonary blood clots in adults.
-
Combining European cohort data to find biomarkers that guide treatment for venous thromboembolism
This project combines clinical, biological and imaging data from European patient cohorts to try to find biomarkers that predict clot recurrence, bleeding, or death in people with venous thromboembolism.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.