Aspiration thrombectomy with the Symphony or Prodigy devices

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study collecting short- and long-term data on the clinical performance and safety of the Symphony and Prodigy thrombectomy systems when used during endovascular procedures in the peripheral or pulmonary vasculature. Adults with a planned procedure using these devices under their intended use are enrolled and followed according to a protocol schedule. Key exclusions include device contraindications, life expectancy under one year, investigator judgment of unsuitability, or inability to complete follow-up. The study is sponsored by Imperative Care, Inc. and is being conducted at Huntsville Hospital in Alabama.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subject is ≥ 18 years of age
2. Subject is willing and able to comply with the follow-up schedule specified in this protocol
3. Subject is willing and able to provide written informed consent prior to any study-related data collection
4. Subject has a planned procedure, involving the use of Imperative Care vascular devices within their intended use

Exclusion Criteria:

1. Subjects with any contraindications per the applicable Instructions for Use
2. Subject with life expectancy of less than 1 year
3. In the opinion of the Investigator, the patient is not a suitable candidate for intervention with Imperative Care devices
4. Subject who may be unable to complete study follow-up
5. Peripheral Venous Cohort ONLY: Presence of thrombus extending more than 2 cm into the IVC on imaging

Where it's running

• Huntsville Hospital
  Huntsville, Alabama, United States Recruiting
• BayCare Health System- Morton Plant Hospital
  Clearwater, Florida, United States Recruiting
• HCA Florida Memorial Hospital
  Jacksonville, Florida, United States Recruiting
• BayCare Health System - St. Joseph Hospital
  Tampa, Florida, United States Recruiting
• Midwest Cardiovascular Institute
  Naperville, Illinois, United States Recruiting
• Profound Research
  Munster, Indiana, United States Recruiting

Study contacts

• Principal investigator: Steven Abramowitz, MD — Medstar Health Research Institute
• Study coordinator: Sylvie Akiel-Fu, MPH
• Email: safu@imperativecare.com
• Phone: 917-375-4735

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Prognostic value of the 2026 AHA/ACC PE classification in ED patients with acute PE

  This study tests whether the 2026 AHA/ACC five-category PE classification helps predict 30-day major adverse pulmonary embolism events in adults with acute PE presenting to the ED.

  Recruiting Marmara University Pendik Training and Research Hospital · Istanbul · NCT07805616

• Predicting thrombosis risk in lung cancer patients on immune therapy

  This study is trying to see if certain factors can help predict the risk of blood clots in lung cancer patients receiving immune therapy.

  Recruiting at 5 sites Beijing Chao Yang Hospital · Zhengzhou, Henan and 4 other locations · NCT06950697

• Timing of anticoagulation for preventing blood clots in patients with brain hemorrhage

  This study is testing whether starting blood-thinning treatment early or later can help prevent blood clots in patients with bleeding in the brain while keeping them safe from more bleeding.

  Recruiting Pirogov Russian National Research Medical University · Moscow · NCT06753786

• Observational study of blood clotting and bleeding disorders in Chinese patients

  This study looks at blood clotting and bleeding problems in Chinese patients to see how common they are and what factors might affect them.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality and 4 other locations · NCT06727669

• Personalized blood thinner treatment for hip and knee replacement patients

  This study is testing if personalized blood thinner treatments can better prevent blood clots and bleeding in patients getting hip or knee replacements compared to standard treatments.

  Recruiting at 12 sites Phase 4 Leiden University Medical Center · Apeldoorn, Gelderland and 12 other locations · NCT06581965

• Evaluating a new decision support tool for diagnosing blood clots

  This study is testing a new tool to help doctors diagnose blood clots in patients who might have conditions like pulmonary embolism or deep vein thrombosis, using fresh blood samples.

  Recruiting at 4 sites Diagnostica Stago R&D · Niort, Sartres and 3 other locations · NCT06480994

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.