Understanding blood clot risks in children with sickle cell disease
Clinical and Molecular based prognostic factors for Venous Thromboembolism (VTE) in Children with Sickle Cell Disease
This study is looking at what might cause blood clots in children with sickle cell disease, so we can find better ways to prevent and treat these clots and help keep kids healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10907804 on NIH RePORTER |
What this research studies
This research investigates the risk factors for blood clots, known as venous thromboembolism (VTE), in children suffering from sickle cell disease (SCD). It aims to identify both clinical and molecular markers that contribute to the development of VTE in this vulnerable population. By analyzing data from multiple centers and collecting biological samples, the study seeks to uncover important insights that could lead to better prevention and treatment strategies. The findings could help healthcare providers better manage the risks associated with SCD in pediatric patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with sickle cell disease, particularly those who have experienced or are at risk for venous thromboembolism.
Not a fit: Patients who do not have sickle cell disease or those over the age of 21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification and management of blood clot risks in children with sickle cell disease, enhancing their overall health outcomes.
How similar studies have performed: While there has been limited research specifically on VTE in pediatric sickle cell disease, similar studies in other populations have shown promising results in identifying risk factors and improving patient outcomes.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Betensky, Marisol — Johns Hopkins University
- Study coordinator: Betensky, Marisol
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.