Validation of Caprini Score for Patients Undergoing Varicose Vein Surgery

A Prospective Cohort Register Study for Validation of Caprini Score in Patients Undergoing Varicose Vein Surgery

Observational Pirogov Russian National Research Medical University · NCT03041805

This study is testing if the Caprini score can help identify adults having varicose vein surgery who are at higher risk for blood clots after their procedure.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages18 Years and up
SexAll
SponsorPirogov Russian National Research Medical University Academic / other
Locations1 site (Moscow)
Trial IDNCT03041805 on ClinicalTrials.gov

What this trial studies

This observational study aims to validate the Caprini score in patients undergoing various types of varicose vein surgeries, particularly focusing on endovascular procedures such as endovenous laser treatment, radiofrequency ablation, and ultrasound-guided foam sclerotherapy. It will enroll adult patients and monitor them for venous thromboembolic complications within 2-4 weeks post-surgery using duplex ultrasound. The study seeks to identify patients at elevated risk for postoperative venous thromboembolism (VTE) who may benefit from prophylactic anticoagulation.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years undergoing any type of varicose vein surgery.

Not a fit: Patients who are lost to follow-up during the 4-week post-operative period may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the identification of patients at risk for VTE, leading to improved prophylactic treatment strategies.

How similar studies have performed: Other studies have shown success in using risk assessment scores like the Caprini score for predicting VTE, indicating that this approach is supported by prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age over 18 years
* any kind of varicose vein surgery
* follow up for 4 weeks after the procedure
* examination for VTE at 2-4 weeks after the procedure, including duplex ultrasound

Exclusion Criteria:

\- lost for follow-up during 4 weeks

Where this trial is running

Moscow

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Venous ThromboembolismVaricose Veinsvenous thromboembolismdeep vein thrombosispulmonary embolismvaricose veinssurgeryendovenous laser treatment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.