Sponsor or institution

Clinical trials and research at University of Rochester

• 93Clinical trials
• 803NIH research projects
• 6Countries

Newest trials

All recruiting trials (93)

• Two-photon microscopy on skin biopsies to help diagnose skin lesions

  This study tests whether images from two-photon fluorescence microscopy of dermatology biopsies can match the diagnosis determined by standard histology.

  Recruiting University of Rochester · Victor, New York · NCT07773688

• Machine learning assessment of two-photon microscopy images from skin biopsies

  A machine learning model is tested on two-photon microscopy images of skin biopsy samples taken in clinic to see if it can correctly predict basal cell carcinoma, squamous cell carcinoma, or non-cancer compared with standard histology.

  Recruiting University of Rochester · Victor, New York · NCT07682831

• Impact of Targeted Therapy on Cancer-Related Cognitive Impairment

  This study checks whether brain health and well‑being differ for people with leukemia who are starting or on TKI therapy compared with similar individuals without cancer or TKI exposure.

  Recruiting University of Rochester · Rochester, New York · NCT07638007

• Personalized cardiac imaging approach for women with early breast cancer on HER2 therapy

  This study tests a personalized, risk-based plan to reduce unnecessary heart imaging while still catching heart problems early in women with HER2-positive breast cancer receiving HER2-targeted therapy.

  Recruiting University of Rochester · Rochester, New York · NCT07630402

• Remote Assessments and Genetic Factors in Congenital and Childhood DM1

  This study tests how congenital, childhood, and juvenile DM1 affect kids by doing remote visits, activities, and a small blood sample to explore symptoms and genetics.

  Recruiting University of Rochester · Rochester, New York · NCT07630389

• Observing Healthy Lung Function with MRI and Breathing Tests

  A study will test whether airway resistance measured by an oscillometer matches ventilation defects seen on PREFUL MRI in healthy adults.

  Recruiting University of Rochester · Rochester, New York · NCT07614685

• Auditory EEG and behavioral testing for people with Rett syndrome

  This project will record noninvasive EEG while people with Rett syndrome and matched controls listen to simple sounds to see how their brains process sound.

  Recruiting University of Rochester · Rochester, New York · NCT07569445

• Home exercise for people with pulmonary hypertension and ILD

  A home-based exercise program is tested to see if people with pulmonary hypertension related to interstitial lung disease can improve walking ability and daily function over 16 weeks.

  Recruiting University of Rochester · Rochester, New York · NCT07561034

• Diphenhydramine added to standard sedation for first-trimester abortion

  This trial tests whether giving diphenhydramine with standard moderate sedation improves pain control during first-trimester uterine aspiration for adults.

  Recruiting Phase 4 University of Rochester · Rochester, New York · NCT07542730

• Impact of Impella 5.5 on heart function in adults with end-stage heart failure

  This study tests whether the Impella 5.5 helps the heart’s two sides work better in adults with severe heart failure who need temporary support.

  Recruiting University of Rochester · Rochester, New York · NCT07534462

• Remote monitoring and genetic analysis for myotonic dystrophy type 1

  This project will test if at-home remote tests plus a blood genetic sample can help explain why symptoms differ among adults with myotonic dystrophy type 1.

  Recruiting University of Rochester · Rochester, New York · NCT07505342

• Engage Coaching for Loneliness in Older Adults

  A coaching program is tested to see if it helps adults 60 and older feel more connected to people in meaningful ways.

  Recruiting University of Rochester · Rochester, New York · NCT07488559

• BriTer Eyez Moisture Vue On-Demand Moisture Chamber for Dry Eye

  This study tests whether wearing the BriTer Eyez Moisture Vue on a two-hour period helps people with mild to moderate dry eye feel and see improvements in tear film and related measures.

  Recruiting University of Rochester · Rochester, New York · NCT07430735

• Pilot randomized test of a social network program for older adults with advanced cancer

  This pilot will try the SONATA social network program to see if it helps adults 65 and older with advanced cancer manage their care better and improve quality of life.

  Recruiting University of Rochester · Rochester, New York · NCT07393529

• Exercise and cognitive rehabilitation for older cancer survivors

  This study will test whether a combined exercise and cognitive rehabilitation program, or exercise or cognitive rehab alone, helps thinking and memory in older adults who have finished cancer treatment.

  Recruiting University of Rochester · Rochester, New York · NCT07390045

• Using oscillometry to link body composition with airway tone and over‑reactivity

  We will test whether a quick oscillometry breathing test can show airway resistance and over‑reactivity related to body habitus in people referred for a methacholine challenge.

  Recruiting University of Rochester · Rochester, New York · NCT07356310

• Self-sampling HPV screening offered in the emergency department

  This project tests whether offering HPV self-sampling in the emergency department helps more people aged 30–65 with a cervix get screened for cervical cancer.

  Recruiting University of Rochester · Rochester, New York · NCT07345897

• Tele-Savvy: Spanish program for Latino caregivers of people with Alzheimer's

  This program tests a Spanish-language, remote caregiver education program to help Latino adults who care for family members with Alzheimer's disease or related dementias improve caregiving skills and reduce stress.

  Recruiting University of Rochester · Rochester, New York · NCT07290387

• Boosting lung cancer screening for patients seen in the emergency department

  This project will test whether giving eligible emergency department patients a facilitated referral plus text reminders helps more people get lung cancer screening.

  Recruiting University of Rochester · Rochester, New York · NCT07287085

• Considering allogeneic stem cell transplant using digital patient stories and values tools

  This program will test whether digital patient stories plus values-clarification exercises help adults with myeloid cancers who are deciding about allogeneic hematopoietic cell transplantation make choices that fit their goals.

  Recruiting University of Rochester · Rochester, New York · NCT07263074

• Optimized pumping protocols to see if milk production improves in new mothers

  This study tests two breast pumping schedules to see if they help lactating parents with low milk supply.

  Recruiting University of Rochester · Rochester, New York · NCT07260968

• rTMS for Fibromyalgia: Brain Changes and Side-to-Side Effects

  This study tests whether repetitive transcranial magnetic stimulation (rTMS) can alter brain activity in people with fibromyalgia and whether brain changes differ when treatment is given to the right vs. left motor cortex.

  Recruiting University of Rochester · Rochester, New York · NCT07260864

• Text messages to boost lung cancer screening participation

  This trial will test whether sending tailored text messages to adults aged 50–80 with a 20+ pack-year smoking history can increase completion of lung cancer screening compared with mailed educational materials.

  Recruiting University of Rochester · Rochester, New York · NCT07227480

• Daridorexant to prevent delirium after heart surgery

  This study will test whether taking daridorexant the first three nights after heart surgery can reduce postoperative delirium and improve sleep in people aged 60 and older.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT07217912

• How higher body mass index affects teens' braces, gums, and tooth health.

  This project will test whether adolescents with higher BMI have more gum inflammation, tooth discoloration, and oral bacteria while wearing fixed braces.

  Recruiting University of Rochester · Rochester, New York · NCT07217756

• Higher caffeine dose to improve breathing in extremely premature babies

  This trial tests whether giving caffeine citrate at 10 mg/kg helps oxygenation in extremely premature infants compared with the standard 5 mg/kg dose.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT07216365

• How vision can recover after an occipital stroke

  This project will use brain MRI and vision testing to see if patterns of residual brain tissue and prior or ongoing visual training relate to partial vision recovery in people with occipital stroke and homonymous field loss.

  Recruiting University of Rochester · Rochester, New York · NCT07134777

• Baby Duchenne: Tracking development in boys with Duchenne muscular dystrophy during their first three years

  This project will follow boys with Duchenne muscular dystrophy found by newborn screening to see how they grow and develop from birth through age three.

  Recruiting at 2 sites University of Rochester · Rochester, New York and 3 other locations · NCT07092540

• Daily text reminders to support pelvic floor exercises after prostate surgery

  This trial will test whether daily text-message reminders help men recovering from prostate surgery keep up pelvic floor exercises and reduce urinary leakage compared with usual care.

  Recruiting University of Rochester · Rochester, New York · NCT07071207

• Reducing Crises and Suicide in the Idaho Army National Guard

  This project tests an enhanced First Line Leaders program with Total Health Action Plan guides to see if it reduces crises and suicidal thoughts among Idaho Army National Guard members.

  Recruiting University of Rochester · Boise, Idaho · NCT07032636

• Thrive person-centered planning for young adults with fetal alcohol spectrum disorders

  This program tests whether the Thrive person-centered planning helps young adults (18–25) with fetal alcohol spectrum disorders improve goal setting, social support, and quality of life by comparing immediate versus delayed start and individual versus group formats.

  Recruiting University of Rochester · Rochester, New York · NCT07016009

• Wearable sensors to track walking and involuntary movements in Huntington's disease

  This study will try whether wrist and body-worn sensors plus virtual visits can track gait changes and chorea in adults with Huntington's disease and in healthy adults.

  Recruiting University of Rochester · Rochester, New York · NCT07010705

• Carvedilol versus metoprolol succinate in people with heart failure and an implanted defibrillator

  This study will test whether switching from metoprolol succinate to carvedilol reduces ICD therapies, heart-related hospitalizations, or cardiovascular death in adults with HFrEF and an ICD.

  Recruiting at 13 sites Phase 4 University of Rochester · Scottsdale, Arizona and 12 other locations · NCT06964464

• Optimizing therapy components for pediatric PTSD with a multiphase design

  This project will try different therapy pieces to see which combinations help children and teens (ages 8–17) with PTSD feel better.

  Recruiting University of Rochester · Rochester, New York · NCT06956781

• Comparing stem cell transplantation to disease-modifying therapy for children with sickle cell disease

  This study is trying to see how well stem cell transplants work compared to other treatments for children with sickle cell disease over three years.

  Recruiting at 16 sites University of Rochester · Birmingham, Alabama and 36 other locations · NCT06941389

• Actívatexto: Helping Latinos quit smoking and become more active

  This trial tests whether Actívatexto, a text-message program combined with wearables and nicotine replacement, helps Latino adults who smoke quit and increase their physical activity.

  Recruiting University of Rochester · Rochester, New York · NCT06926608

• Visual perception in schizophrenia and related disorders

  We will test whether EEG recordings of visual processing can find brain markers of psychosis in adults with schizophrenia, schizoaffective disorder, or bipolar disorder.

  Recruiting University of Rochester · Rochester, New York · NCT06911931

• Mosunetuzumab consolidation for older DLBCL patients with detectable ctDNA after pola‑R‑mini‑CHP

  This trial will try mosunetuzumab in older people with DLBCL who have detectable ctDNA after finishing pola‑R‑mini‑CHP to see if it clears leftover cancer DNA and lowers the chance of relapse.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT06828991

• Adapting the FOCUS Program for LGBTQ+ Cancer Patients and Caregivers

  This trial tests a tailored version of the FOCUS program to see if it helps LGBTQ+ cancer patients and their informal caregivers, compared with a waitlist control.

  Recruiting at 2 sites University of Rochester · Detroit, Michigan and 1 other locations · NCT06800053

• Healthy living strategies to help recover from pulmonary embolism

  This study tests if two healthy living strategies can help people recover better after being hospitalized for a pulmonary embolism.

  Recruiting University of Rochester · Rochester, New York · NCT06784492

• Comparing two types of bone grafts for tooth replacement

  This study is testing which of two types of bone grafts helps people keep their jawbone healthy after losing a front tooth before getting a dental implant.

  Recruiting University of Rochester · Rochester, New York · NCT06722482

• Decision support for older adults with acute myeloid leukemia and their caregivers

  This will test a decision-support program (UR-GOAL) to help people 60 and older with newly diagnosed AML and their caregivers make treatment decisions.

  Recruiting at 4 sites University of Rochester · Birmingham, Alabama and 3 other locations · NCT06697600

• Comparing breast milk feeding methods for infants

  This study is testing how different ways of feeding breast milk to babies affect their sleep and gut health, and it's for families who use pumped breast milk.

  Recruiting University of Rochester · Rochester, New York · NCT06691932

• Using the My Health Coach app to help adults with fetal alcohol spectrum disorders

  This study is testing whether using the My Health Coach app can help improve the quality of life for adults with fetal alcohol spectrum disorders.

  Recruiting University of Rochester · Rochester, New York · NCT06638463

• Sensory testing to guide medication choice for painful peripheral neuropathy

  This will try to see if sensory testing can predict which people with painful peripheral neuropathy get more pain relief from duloxetine or pregabalin than from placebo.

  Recruiting at 7 sites Phase 2 University of Rochester · Boston, Massachusetts and 6 other locations · NCT06614322

• Evaluating breathing difficulties using exercise testing and oscillometry

  This study is trying to see if measuring airway resistance during breathing tests can help understand the causes of shortness of breath in people who have been referred for exercise testing.

  Recruiting University of Rochester · Rochester, New York · NCT06554353

• Preventive ventricular tachycardia ablation for high-risk patients receiving a primary ICD

  This will test whether doing catheter-based preventive VT ablation within three months of getting a primary ICD reduces ventricular tachycardia events in people with ischemic cardiomyopathy and low ejection fraction.

  Recruiting at 5 sites University of Rochester · Copenhagen, Region H and 4 other locations · NCT06543173

• Resilient Roots: Support for youth and families affected by child abuse and neglect

  This project will test whether adding a family- and community-focused socialization component to Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) helps 10–15-year-olds who experienced child abuse or neglect reduce trauma symptoms and improve coping.

  Recruiting University of Rochester · Rochester, New York · NCT06535516

• Using advanced imaging to improve surgery for skin cancer

  This study is testing a new imaging technique to see if it can help doctors remove all of the skin cancer during surgery.

  Recruiting University of Rochester · Victor, New York · NCT06473103

• Intervention for opioid use disorder and loneliness

  This study is testing whether different types of therapy can help people with opioid use disorder who feel lonely improve their social connections and overall health.

  Recruiting University of Rochester · Rochester, New York · NCT06458335

• Helping older patients with kidney disease make treatment decisions

  This study is testing which type of support helps older patients with kidney disease make better treatment choices, either through a kidney educator or a decision-support specialist.

  Recruiting at 5 sites University of Rochester · Brockport, New York and 4 other locations · NCT06410144

• Improving HPV vaccination rates through standing orders

  This study tests if allowing healthcare team members to give HPV vaccines without needing a doctor's order can help more kids aged 11-12 get vaccinated.

  Recruiting University of Rochester · Rochester, New York · NCT06380114

• Using TENS for pain relief during outpatient urethral bulking in women with stress urinary incontinence.

  This study is testing if using a TENS machine can help reduce pain for women undergoing a specific procedure for stress urinary incontinence.

  Recruiting University of Rochester · Rochester, New York · NCT06369922

• Disulfiram (Antabuse) for vision in retinal degeneration

  This study will test whether taking oral disulfiram (Antabuse) improves vision in adults with retinal degeneration who are also being treated for alcohol use disorder.

  Recruiting Phase 1 University of Rochester · Rochester, New York · NCT06319872

• Improving communication for older adults with dementia facing cancer decisions

  This study is testing a new way to help older adults with dementia and their caregivers communicate better when making decisions about cancer treatment.

  Recruiting University of Rochester · Rochester, New York · NCT06313853

• Radiation therapy for high-risk metastatic lung cancer patients

  This study is testing if adding radiation therapy to standard treatment can help high-risk lung cancer patients feel better and slow down their disease.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT06262321

• Maternal peanut and egg consumption versus avoidance during pregnancy and breastfeeding

  This study will test whether mothers eating or avoiding peanuts and eggs from late pregnancy through breastfeeding changes babies' chances of developing peanut or egg allergies.

  Recruiting University of Rochester · Rochester, New York · NCT06260956

• Visual retraining after stroke

  We will try an intensive home-based visual retraining program for adults with cortical vision loss after stroke to see if it improves visual perception and everyday use of vision.

  Recruiting University of Rochester · Rochester, New York · NCT06121219

• Observational study on cancer cachexia subtypes

  This study is trying to identify different types of weight and muscle loss in patients with advanced colorectal, lung, or pancreatic cancers to help improve future treatments.

  Recruiting at 196 sites University of Rochester · Fort Smith, Arkansas and 224 other locations · NCT06073431

• Understanding how vision loss affects driving in virtual reality

  This study tests how vision loss from a stroke affects driving skills in a virtual reality setting to help understand the challenges faced by people with visual field defects.

  Recruiting University of Rochester · Rochester, New York · NCT06047717

• Testing a new app for mental health providers to support families affected by fetal alcohol spectrum disorders

  This study is testing a new app to see if it helps mental health providers better support families affected by fetal alcohol spectrum disorders using two different training methods.

  Recruiting University of Rochester · Rochester, New York · NCT05960461

• Evaluating a new radiation treatment for recurrent prostate cancer after surgery

  This study is testing a new type of radiation treatment for men with recurring prostate cancer after surgery to see if it works better and is easier than the usual methods.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT05946824

• Digital RITch®CBT versus standard one-on-one CBT for men with substance use and partner aggression

  This trial will test whether a self-guided digital program called RITch®CBT helps men in addiction treatment who have recently shown aggression toward intimate partners, compared with standard one-on-one CBT.

  Recruiting University of Rochester · Rochester, New York · NCT05943171

• Telehealth program for advance care planning in older adults with myeloid malignancies

  This study tests if a telehealth program that helps older adults with blood cancers talk about their serious illness and make healthcare plans can reduce their anxiety and improve communication with doctors.

  Recruiting University of Rochester · Rochester, New York · NCT05875805

• Telehealth support for children with asthma after emergency room visits

  This study is testing a new telehealth program to see if it helps children aged 3-12 manage their asthma better after they leave the emergency room.

  Recruiting University of Rochester · Rochester, New York · NCT05844891

• High-dose vitamin D for bone health in older prostate cancer patients on hormone therapy

  This study is testing if high-dose vitamin D can help older prostate cancer patients on hormone therapy keep their bones strong and reduce the risk of falls and fractures.

  Recruiting at 51 sites Phase 3 University of Rochester · Newark, Delaware and 50 other locations · NCT05838716

• A program to support older cancer patients through social networks

  This study is testing a new support program that helps older cancer patients connect with others during their treatment to see if they find it helpful and if they stick with it.

  Recruiting University of Rochester · Rochester, New York · NCT05745038

• Using Selinexor to Treat High-Risk Smoldering Multiple Myeloma

  This study is testing if a low dose of selinexor can help people with high-risk smoldering multiple myeloma delay the progression to full-blown multiple myeloma.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT05597345

• Determining the best dose of lisinopril to prevent urinary issues after prostate cancer radiotherapy

  This study is testing the best dose of lisinopril to see if it can help men with prostate cancer avoid urinary problems after radiation treatment.

  Recruiting Early Phase 1 University of Rochester · Rochester, New York · NCT05530655

• Investigating meningitis causes and prevention in rural Uganda

  This study is trying to understand the causes and prevention of meningitis in rural Uganda by looking at patients with symptoms and screening HIV-positive individuals to improve care and vaccination efforts.

  Recruiting University of Rochester · Lira · NCT05496673

• Combined mobile exercise and cognitive rehabilitation for older cancer survivors

  This pilot will test a combined mobile exercise and cognitive rehabilitation program to see if it improves thinking and memory in older cancer survivors who have finished treatment.

  Recruiting University of Rochester · Rochester, New York · NCT05388214

• Investigating how dopamine affects chronic pain

  This study is testing how changes in dopamine levels might affect chronic pain in patients by using different treatments and brain scans to see what happens.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT05285683

• Evaluating His-Bundle Pacing for Heart Failure Treatment

  This study is testing if a new heart pacing method can help people with heart failure and a specific heart block feel better compared to the standard treatment.

  Recruiting at 14 sites University of Rochester · Phoenix, Arizona and 13 other locations · NCT05265520

• Living donor liver transplant for patients with colorectal cancer spread to the liver

  This study is trying to see how well living donor liver transplants work for people with colorectal cancer that has spread to the liver by collecting information on their survival and recovery.

  Recruiting University of Rochester · Rochester, New York · NCT05248581

• Imaging lymphatic vessels in people with rheumatoid arthritis

  This study is testing a special imaging technique to see how well treatments work for people with rheumatoid arthritis by looking at changes in their lymphatic vessels over time.

  Recruiting Phase 1 University of Rochester · Rochester, New York · NCT05197530

• Combining renal denervation with pulmonary vein isolation for treating persistent atrial fibrillation

  This study is testing if combining a new kidney treatment with a common heart procedure can help people with ongoing atrial fibrillation feel better and have fewer heart rhythm problems.

  Recruiting University of Rochester · Short Hills, New Jersey · NCT05116384

• Investigating VTA Ablation in Patients with Left Ventricular Assist Devices

  This study is testing if a procedure to stop fast heartbeats during surgery for a heart pump can help patients with a history of those fast heartbeats feel better after the surgery.

  Recruiting at 19 sites Phase 4 University of Rochester · Phoenix, Arizona and 18 other locations · NCT05034432

• Geriatric evaluation and management program for older cancer survivors

  This study is testing if a special program that combines health education and support can help older cancer survivors feel better and improve their daily life after finishing chemotherapy.

  Recruiting at 44 sites Phase 3 University of Rochester · Tuscaloosa, Alabama and 44 other locations · NCT05006482

• Mobile health exercise program for older adults with myeloid neoplasms

  This study is testing a mobile health exercise program to see if it can help older adults with myeloid neoplasms feel better and maintain their physical abilities while they are receiving chemotherapy.

  Recruiting University of Rochester · Rochester, New York · NCT04981821

• Neratinib and Capecitabine for HER2-Negative Breast Cancer with Brain Metastases

  This study is testing if a combination of neratinib and capecitabine can help people with HER2-negative breast cancer that has spread to the brain.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT04965064

• Using electrical stimulation to relieve dry mouth in head and neck cancer patients after radiation

  This study is testing if a new electrical therapy can help relieve dry mouth symptoms in head and neck cancer patients who have had radiation treatment.

  Recruiting University of Rochester · Rochester, New York · NCT04805528

• Telehealth discussions about end-of-life care for patients with high grade glioma

  This study is trying to see if telehealth visits can help patients with high grade glioma and their families have important conversations about end-of-life care planning.

  Recruiting University of Rochester · Rochester, New York · NCT04543201

• Pembrolizumab plus single-agent chemotherapy as first-line treatment for advanced non-small cell lung cancer in patients with ECOG performance status 2

  This trial will try pembrolizumab with one chemotherapy drug as first treatment to see if it is tolerable and helps people with advanced non-small cell lung cancer who have an ECOG performance status of 2.

  Recruiting Phase 1 University of Rochester · Rochester, New York and 1 other locations · NCT04297605

• Understanding skin bacteria in patients with eczema and psoriasis

  This study is trying to see how skin bacteria affect people with eczema and psoriasis to better understand their skin health and treatment responses.

  Recruiting University of Rochester · Rochester, New York · NCT04170244

• Understanding how aging and disease affect motion perception

  This study is testing how aging and vestibular disease affect how people see and feel motion to help improve balance and prevent falls.

  Recruiting University of Rochester · Rochester, New York · NCT04142697

• Using hyperbaric oxygen therapy with stem cell transplants

  This study is testing whether hyperbaric oxygen therapy can help patients with chronic leukemias and myelofibrosis who are getting stem cell transplants feel better and recover more effectively.

  Recruiting Early Phase 1 University of Rochester · Rochester, New York · NCT03964506

• Using PET scans and blood tests to improve treatment for early stage lymphoma

  This study is testing if measuring tumor DNA in the blood can help doctors adjust treatment for patients with early stage lymphoma to improve their chances of success.

  Recruiting Phase 2 University of Rochester · Rochester, New York · NCT03758989

• Comparing two schedules of radiation for early-stage lung cancer

  This study is testing whether different schedules of radiation therapy for early-stage lung cancer cause different side effects for patients.

  Recruiting University of Rochester · Rochester, New York · NCT03706027

• Understanding how chemotherapy affects cognitive function in breast cancer patients

  This study looks at how chemotherapy affects thinking and memory in newly diagnosed breast cancer patients compared to people without cancer.

  Recruiting University of Rochester · Rochester, New York · NCT03137095

• Transplanting umbilical cord blood from unrelated donors

  This study is testing different ways to prepare patients for umbilical cord blood stem cell transplants to see how safe and effective the procedure is for them.

  Recruiting University of Rochester · Rochester, New York · NCT03016806

• Investigating Batten disease and its effects

  This study is trying to understand how Batten disease affects movement, behavior, and daily life by collecting information from people with the condition over time.

  Recruiting University of Rochester · Rochester, New York · NCT01873924

• Monitoring minimal residual disease in patients with acute myeloid leukemia or myelodysplastic syndrome

  This study is trying to see if new tests can help find hidden cancer cells in patients with acute myeloid leukemia or myelodysplastic syndrome who seem to be in remission, to better understand their risk of relapse.

  Recruiting University of Rochester · Rochester, New York · NCT01311258

• Registry for Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy

  This study is creating a registry for people with myotonic dystrophy or facioscapulohumeral muscular dystrophy to share their health information and connect with researchers working to learn more about these conditions.

  Recruiting University of Rochester · Rochester, New York · NCT00082108

NIH-funded research (newest 40 of 803)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Rapid automated breast lump diagnosis without a radiologist or sonographer

  A new AI-powered ultrasound tool helps determine if a palpable breast lump is likely benign or malignant, using a simplified technique that can be used by people with minimal ultrasound training.

  NIH research University of Rochester · Rochester, United States · NIH-11624472

• ML-ROVER: Reducing Unneeded Lab Tests in Kids with AI

  Aims to use machine learning to cut unnecessary blood tests in children in intensive care, helping avoid anemia and improve care quality.

  NIH research University of Rochester · Rochester, United States · NIH-11607116

• Aggressive fever-reducing therapy to protect the brains of children with CNS malaria

  A study planned for children with CNS malaria will test whether aggressive fever-reducing treatment can lower death and brain-related problems.

  NIH research University of Rochester · Rochester, United States · NIH-11604407

• Aggressive fever-reducing therapy to protect brains in children with CNS malaria

  A plan to test whether giving strong fever-reducing medications to children with central nervous system malaria can lower death and brain injury.

  NIH research University of Rochester · Rochester, United States · NIH-11604392

• Aggressive fever-fighting treatment to protect the brain in kids with CNS malaria

  A plan to test whether giving strong fever-reducing treatment alongside standard care can lower death and brain injury in children with CNS malaria.

  NIH research University of Rochester · Rochester, United States · NIH-11604356

• Aggressive fever-reducing treatment to protect brains in kids with CNS malaria

  A plan to test whether giving strong fever-reducing medicine alongside standard malaria treatment can lower deaths and brain injuries in children with CNS malaria.

  NIH research University of Rochester · Rochester, United States · NIH-11604355

• Aggressive fever-reducing treatment to protect the brain in children with CNS malaria

  A study tests whether giving strong fever-reducing medicines alongside standard care can lower death and brain-related problems in children with severe malaria affecting the brain.

  NIH research University of Rochester · Rochester, United States · NIH-11604354

• Aggressive fever-reducing therapy to protect the brain in children with CNS malaria

  This project plans a large, multi-country trial to test whether aggressive fever control helps reduce death and brain injury in African children with CNS malaria.

  NIH research University of Rochester · Rochester, United States · NIH-11604353

• Multi-level HIV prevention in Ghana through community pharmacies

  A multi-level program tests using community pharmacies in Ghana to boost HIV testing and PrEP uptake among men at high risk.

  NIH research University of Rochester · Rochester, United States · NIH-11587443

• How air pollution affects recurrent heart events in older adults

  This grant explores how air pollution, especially PM2.5, influences the recurrence and progression of heart problems in people aged 65 and older.

  NIH research University of Rochester · Rochester, United States · NIH-11568469

• A Small Molecule PROTAC for Macular Degeneration

  A patient-friendly look at a small molecule therapy designed to target a key inflammation driver in age-related macular degeneration to help protect vision.

  NIH research University of Rochester · Rochester, United States · NIH-11564143

• University of Rochester IDD Research Center focusing on autism and neurodevelopment

  A comprehensive research center at the University of Rochester is coordinating multiple scientific cores to study autism and other developmental disorders, with the goal of advancing understanding and care for people with these conditions.

  NIH research University of Rochester · Rochester, United States · NIH-11551654

• ECG-BASED smart tools to quickly classify chest pain in emergency care

  A patient-focused project to use advanced ECG analysis and machine learning to quickly identify heart problems in people with chest pain when they arrive at the ER.

  NIH research University of Rochester · Rochester, United States · NIH-11550067

• URCC NCORP Research Base

  A cancer care research program helps community clinics improve how they support people with cancer and reduce treatment-related side effects.

  NIH research University of Rochester · Rochester, United States · NIH-11543567

• ESCAPE: Understanding how moms’ diets affect peanut and egg allergy risk in infants

  A study following pregnant and breastfeeding families to understand how early exposure to peanut and egg might influence allergy risk in babies.

  NIH research University of Rochester · Rochester, United States · NIH-11543416

• Understanding cancer cachexia and its drivers to improve quality of life for patients

  A research project at the University of Rochester is studying why cancer patients lose weight and muscle and how this worsens outcomes, with the goal of finding new ways to help patients feel better and stay stronger.

  NIH research University of Rochester · Rochester, United States · NIH-11539623

• Adaptation of a proven HIV prevention approach to help Ghanaian young men increase HIV self-testing

  A project adapts a well-known HIV prevention program to help young men in Ghana’s slums learn about and use HIV self-testing, aiming to reduce stigma and improve access to testing.

  NIH research University of Rochester · Rochester, United States · NIH-11526486

• FcgR-activated neutrophils shaping T cells in kidney and vessel inflammation

  This NIH grant explores how a specific neutrophil behavior may drive harmful T-cell activity in lupus-related kidney inflammation and vasculitis, with potential to inform new treatments.

  NIH research University of Rochester · Rochester, United States · NIH-11523442

• Acid-sensing ion channels: how they change shape and what that means for cancer and the brain

  This NIH grant explores how acid-sensing ion channels (ASICs) change shape and work together in the nervous system and in cancers, to uncover new ways that cells respond to acidity.

  NIH research University of Rochester · Rochester, United States · NIH-11509246

• Trusted school messengers boosting non-mandated vaccines for kids

  A school-based program aims to increase uptake of vaccines like influenza and HPV among children by using trusted school staff to share accurate vaccine information.

  NIH research University of Rochester · Rochester, United States · NIH-11503940

• Immune complex signals steering neutrophils into powerful antigen-presenting cells in autoimmune kidney disease

  This project looks at how immune system problems involving neutrophils may drive autoimmune diseases of the kidneys by turning neutrophils into cells that activate T cells.

  NIH research University of Rochester · Rochester, United States · NIH-11473498

• FastPlex: A fast deep-learning tool to map the choroid plexus in brain scans

  A new open-source deep-learning method will quickly and accurately segment the choroid plexus in brain MRIs to study aging and Alzheimer’s-related brain changes.

  NIH research University of Rochester · Rochester, United States · NIH-11473274

• Targeting the cancer-friendly environment around blood stem cells in AML

  Researchers are studying how the bone marrow surroundings influence acute myeloid leukemia and whether changing those signals could help people with AML.

  NIH research University of Rochester · Rochester, United States · NIH-11473222

• How bone marrow stem cells' cleanup affects bone aging

  This work looks at whether changing how bone marrow stem cells clear dying cells can help keep older adults' bones stronger.

  NIH research University of Rochester · Rochester, United States · NIH-11472060

• Treating IGF‑1R–positive breast cancer by targeting soluble E‑cadherin

  This project develops a treatment that blocks a protein called soluble E‑cadherin to help people whose breast tumors show high IGF‑1R activity.

  NIH research University of Rochester · Rochester, United States · NIH-11471512

• Improving HIV PrEP delivery by providers in the U.S.

  A short-term grant to help doctors, nurses, and other health workers better identify people at risk and prescribe HIV PrEP, and to keep patients using it over time.

  NIH research University of Rochester · Rochester, United States · NIH-11470888

• Family caregiver programs in nursing homes and dementia care outcomes

  This grant studies how state essential caregiver programs during 2020-2021 affected the care and outcomes of nursing home residents with Alzheimer's disease and related dementias.

  NIH research University of Rochester · Rochester, United States · NIH-11463422

• Scalable platform to map RNA viruses that infect bacteria

  A new project will build a rapid, inside-bacteria system to identify which RNA viruses and circular RNA elements can infect specific bacteria found in the human microbiome, helping us understand their roles in health and disease.

  NIH research University of Rochester · Rochester, United States · NIH-11456935

• Geriatric assessments to guide cancer care for older adults with advanced cancer

  A study tests a geriatric assessment–based approach to tailor cancer treatment in older adults with advanced cancer to reduce side effects and keep patients at home longer.

  NIH research University of Rochester · Rochester, United States · NIH-11452992

• Macrophages shaping aging blood stem cells in the bone marrow

  This NIH grant explores how certain bone marrow macrophages help protect blood-forming stem cells as we age, with potential implications for anemia and healthier aging.

  NIH research University of Rochester · Rochester, United States · NIH-11452476

• Point-of-care RH risk tool for refeeding in anorexia nervosa

  A quick, clinician-friendly risk tool helps predict who with anorexia nervosa might develop dangerous low phosphorus during hospitalization, guiding safer feeding and monitoring.

  NIH research University of Rochester · Rochester, United States · NIH-11451994

• Longitudinal imaging to predict bone fracture healing using light-based tech

  Aims to use safe light-based imaging over time to see how healing bones in people with fractures progress and whether early signals predict problems.

  NIH research University of Rochester · Rochester, United States · NIH-11449366

• Protective role of MIRO1 in lung blood-vessel injury

  A study at the University of Rochester will explore how a protein called MIRO1 helps lung blood vessels stay intact during severe lung injury, with the goal of guiding new therapies for people with ALI/ARDS.

  NIH research University of Rochester · Rochester, United States · NIH-11447485

• ORAI Channels and Brain Blood Flow in Aging

  A study to understand how age-related changes in ORAI channels affect brain blood flow and neurovascular signaling in people with Alzheimer's-related conditions.

  NIH research University of Rochester · Rochester, United States · NIH-11447232

• Attention-based perceptual learning for people with cortically blindness after stroke

  A stroke-related vision loss condition is targeted with a training program that uses attention-driven exercises to improve visual perception.

  NIH research University of Rochester · Rochester, United States · NIH-11446726

• Bile acid signals and social behavior in mice

  This grant tests how bile acids they smell influence social behavior in mice, aiming to understand how these chemical cues shape choices and interactions.

  NIH research University of Rochester · Rochester, United States · NIH-11446619

• Emerging nicotine analogs and device design that may affect safety

  This grant explores whether new nicotine-like chemicals in vaping products and how different device designs change toxin levels could affect lung health.

  NIH research University of Rochester · Rochester, United States · NIH-11446555

• Understanding how disorganized parental conflict affects children’s mental health

  This grant studies how chaotic, unpredictable parental conflicts influence kids’ mental health and what makes some children more vulnerable than others.

  NIH research University of Rochester · Rochester, United States · NIH-11446358

• Calcium Channel Blocker in DM1: Can amlodipine help myotonic dystrophy type 1

  This study tests whether the calcium‑channel blocker amlodipine can improve symptoms and survival in myotonic dystrophy type 1 (DM1).

  NIH research University of Rochester · Rochester, United States · NIH-11444061

• Immunomodulation to treat and prevent Pneumocystis pneumonia in people with AIDS or weakened immune systems

  This grant explores a drug already approved for other uses to help people with AIDS or similar conditions fight Pneumocystis pneumonia more effectively.

  NIH research University of Rochester · Rochester, United States · NIH-11443193

Quick answers

How many clinical trials run by University of Rochester are recruiting right now?

93, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (91 trials), Canada (1 trial), Denmark (1 trial), France (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 10, Phase 4: 3, Phase 1: 3, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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