Observing Healthy Lung Function with MRI and Breathing Tests

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will compare airway resistance measurements from an oscillometry device with ventilation patterns captured by Phase Resolved Functional Lung MRI in healthy volunteers. Participants will undergo a breath test and an MRI scan to look for relationships between airway mechanics and lung ventilation. The study is conducted at University of Rochester Medical Center and does not involve an intervention beyond standard testing procedures. No treatment will be provided or withheld based on results, and findings will be used to better understand normal lung function. Eligible participants are adults 18 and older who can consent and communicate in English.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Ability to provide consent
* Willingness to perform MRI and breathing test
* Must be able to speak and understand English

Exclusion Criteria:

* Pregnant
* Unable or willing to provide consent or perform the required maneuvers for testing.

Where it's running

• University of Rochester Medical Center
  Rochester, New York, United States Recruiting

Study contacts

• Study coordinator: Patrick Donohue, MD
• Email: patrick_donohue@urmc.rochester.edu
• Phone: 585-210-9301

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Low-Field MRI in Emergency Stroke Care

  This study tests whether a portable low-field MRI can help detect acute stroke in patients arriving with suspected stroke.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT07702968

• Using oscillometry to link body composition with airway tone and over‑reactivity

  We will test whether a quick oscillometry breathing test can show airway resistance and over‑reactivity related to body habitus in people referred for a methacholine challenge.

  Recruiting University of Rochester · Rochester, New York · NCT07356310

• Minimally invasive surgery for patients with impaired lung function

  This study is testing a new type of surgery that lets patients with weak lungs breathe on their own during the operation to see if it helps them recover better after surgery.

  Recruiting The Second Hospital of Shandong University · Jinan, Shandong · NCT06848751

• Evaluating breathing difficulties using exercise testing and oscillometry

  This study is trying to see if measuring airway resistance during breathing tests can help understand the causes of shortness of breath in people who have been referred for exercise testing.

  Recruiting University of Rochester · Rochester, New York · NCT06554353

• SPECT-guided radiation that spares well-functioning lung during curative lung cancer treatment

  This trial will test whether using perfusion SPECT/CT to guide radiation plans that avoid highly functional lung reduces radiation-related lung damage for adults receiving curative chemo-radiation for lung cancer.

  Recruiting at 2 sites University of Aarhus · Sydney, New South Wales and 1 other locations · NCT04676828

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.