Understanding how aging and disease affect motion perception
Visual and Vestibular Percepts of Motion
This study is testing how aging and vestibular disease affect how people see and feel motion to help improve balance and prevent falls.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University of Rochester Academic / other |
| Locations | 1 site (Rochester, New York) |
| Trial ID | NCT04142697 on ClinicalTrials.gov |
What this trial studies
This study aims to measure sensitivity to visual and vestibular motion perception in both healthy individuals and patients with vestibular disease. It investigates how visual and inertial stimuli are integrated to form a unified perception of self-motion, which is crucial for understanding fall risk and other conditions. The study will develop methods to assess causal inference in motion perception and explore the potential for creating new vestibular rehabilitation techniques. By examining these processes, researchers hope to gain insights into the effects of aging and disease on motion perception.
Who should consider this trial
Good fit: Ideal candidates include healthy individuals in good health and patients with unilateral or bilateral vestibular loss who are also in good health.
Not a fit: Patients with significant sensory, motor, or cognitive impairments that prevent them from performing study tasks may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation methods for patients with vestibular disorders and enhance understanding of motion perception in aging populations.
How similar studies have performed: While there has been limited research on causal inference in motion perception, this study's approach is innovative and may pave the way for new insights in the field.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Healthy subjects: * general good health Vestibular Disease patients: * general good health * specific unilateral or bilateral vestibular loss Exclusion Criteria: Healthy subjects: * subjects who are institutionalized or otherwise not self-sufficient. * enduring sequelae due to diseases of the nervous system, eyes, ears, head and neck, and limbs, except for changes commensurate with normal aging (e.g. presbyacusic hearing loss, mild cataract, etc.). * abnormal cognitive function, which if in question can be determined as a score of \<27 on the Mini-Mental State test. * corrected visual acuity worse than 20/20 up to age 65, worse than 20/40 if \>65 * abnormal binocular stereo-acuity or visual fields. * any defects in cranial nerve, oculomotor, cerebellar/coordination, and somatosensory functions. * any abnormal oculomotor and vestibular function (caloric tests) Vestibular Disease patients: * Inability to perform the study tasks due to sensory, motor, or postural limitations
Where this trial is running
Rochester, New York
- University of Rochester Medical Center — Rochester, New York, United States (Recruiting)
Study contacts
- Study coordinator: Cesar Arduino
- Email: Cesar_Arduino@urmc.rochester.edu
- Phone: 585-273-2043
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.