Understanding how aging and disease affect motion perception
Official title: Visual and Vestibular Percepts of Motion
Run by University of Rochester · NCT04142697 · Data updated 2026-11-12
This study is testing how aging and vestibular disease affect how people see and feel motion to help improve balance and prevent falls.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | University of Rochester Academic / other |
| Locations | 1 site (Rochester, New York) |
| Status | Recruiting |
| Started | September 15, 2020 |
| Main results expected | September 1, 2030 |
| Study ends | September 1, 2032 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT04142697 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include healthy individuals in good health and patients with unilateral or bilateral vestibular loss who are also in good health.
✕Probably not a fit
Patients with significant sensory, motor, or cognitive impairments that prevent them from performing study tasks may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to measure sensitivity to visual and vestibular motion perception in both healthy individuals and patients with vestibular disease. It investigates how visual and inertial stimuli are integrated to form a unified perception of self-motion, which is crucial for understanding fall risk and other conditions. The study will develop methods to assess causal inference in motion perception and explore the potential for creating new vestibular rehabilitation techniques. By examining these processes, researchers hope to gain insights into the effects of aging and disease on motion perception.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation methods for patients with vestibular disorders and enhance understanding of motion perception in aging populations.
How similar studies have gone: While there has been limited research on causal inference in motion perception, this study's approach is innovative and may pave the way for new insights in the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Healthy subjects: * general good health Vestibular Disease patients: * general good health * specific unilateral or bilateral vestibular loss Exclusion Criteria: Healthy subjects: * subjects who are institutionalized or otherwise not self-sufficient. * enduring sequelae due to diseases of the nervous system, eyes, ears, head and neck, and limbs, except for changes commensurate with normal aging (e.g. presbyacusic hearing loss, mild cataract, etc.). * abnormal cognitive function, which if in question can be determined as a score of \<27 on the Mini-Mental State test. * corrected visual acuity worse than 20/20 up to age 65, worse than 20/40 if \>65 * abnormal binocular stereo-acuity or visual fields. * any defects in cranial nerve, oculomotor, cerebellar/coordination, and somatosensory functions. * any abnormal oculomotor and vestibular function (caloric tests) Vestibular Disease patients: * Inability to perform the study tasks due to sensory, motor, or postural limitations
Where it's running
-
University of Rochester Medical Center
Rochester, New York, United States Recruiting
Study contacts
- Study coordinator: Cesar Arduino
- Email: Cesar_Arduino@urmc.rochester.edu
- Phone: 585-273-2043
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.