Two-photon microscopy on skin biopsies to help diagnose skin lesions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will image freshly obtained skin biopsy samples using two-photon fluorescence microscopy and compare these images to the final histology diagnoses read by a pathologist. The study will also evaluate a machine learning model's ability to predict the same diagnoses from the microscopy images. The goal is to see if rapid, clinic-based imaging can support immediate or faster decision-making about skin lesions. Conventional histology remains the gold standard for comparison. No treatment is altered by this imaging approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Punch, excisional or shave biopsy specimen

Exclusion Criteria:

* Biopsies composed of multiple excisions or pieces

Where it's running

• Rochester Dermatologic Surgery
  Victor, New York, United States Recruiting

Study contacts

• Study coordinator: Michael G Giacomelli, Ph.D
• Email: mgiacome@ur.rochester.edu
• Phone: 5852766260

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.