Using advanced imaging to improve surgery for skin cancer
Investigation of Standard Excision Surgical Margins Using Two Photon Fluorescence Microscopy
This study is testing a new imaging technique to see if it can help doctors remove all of the skin cancer during surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 52 (estimated) |
| Sex | All |
| Sponsor | University of Rochester Academic / other |
| Locations | 1 site (Victor, New York) |
| Trial ID | NCT06473103 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of two photon fluorescence microscopy (TPFM) in detecting residual basal cell carcinoma during standard local excision procedures. The study will involve fluorescently labeling excised tissue and measuring the distance to inked surgical margins using TPFM, followed by standard permanent section evaluations for confirmation. By comparing the results from TPFM with traditional methods, the study seeks to enhance surgical outcomes and ensure complete removal of cancerous tissue.
Who should consider this trial
Good fit: Ideal candidates are patients undergoing treatment for basal cell carcinoma who are not receiving Mohs surgery.
Not a fit: Patients who are not undergoing surgical treatment for basal cell carcinoma or those receiving Mohs surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate surgical margins and better outcomes for patients with basal cell carcinoma.
How similar studies have performed: While the use of advanced imaging techniques in surgical oncology is gaining traction, this specific application of TPFM for basal cell carcinoma is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing treatment for basal cell carcinoma without Mohs surgery at the performance site * Able to read and understand consent form Exclusion Criteria: * None
Where this trial is running
Victor, New York
- Rochester Dermatologic Surgery — Victor, New York, United States (Recruiting)
Study contacts
- Principal investigator: Michael Giacomelli — University of Rochester
- Study coordinator: Michael Giacomelli, Ph.D.
- Email: mgiacome@ur.rochester.edu
- Phone: 5852766260
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.