Clinical trial Recruiting at 1 site Interventional

Using advanced imaging to improve surgery for skin cancer

Official title: Investigation of Standard Excision Surgical Margins Using Two Photon Fluorescence Microscopy

Run by University of Rochester · NCT06473103 · Data updated 2026-11-12

This study is testing a new imaging technique to see if it can help doctors remove all of the skin cancer during surgery.

Quick facts

Study typeInterventional
SexAll
Enrollment52 (estimated)
SponsorUniversity of Rochester
Academic / other
Locations1 site (Victor, New York)
StatusRecruiting
StartedOctober 29, 2024
Main results expectedMarch 2026
Study endsApril 2026
Registry record updatedMarch 17, 2025
Trial IDNCT06473103 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients undergoing treatment for basal cell carcinoma who are not receiving Mohs surgery.

Probably not a fit

Patients who are not undergoing surgical treatment for basal cell carcinoma or those receiving Mohs surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of two photon fluorescence microscopy (TPFM) in detecting residual basal cell carcinoma during standard local excision procedures. The study will involve fluorescently labeling excised tissue and measuring the distance to inked surgical margins using TPFM, followed by standard permanent section evaluations for confirmation. By comparing the results from TPFM with traditional methods, the study seeks to enhance surgical outcomes and ensure complete removal of cancerous tissue.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate surgical margins and better outcomes for patients with basal cell carcinoma.

How similar studies have gone: While the use of advanced imaging techniques in surgical oncology is gaining traction, this specific application of TPFM for basal cell carcinoma is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Undergoing treatment for basal cell carcinoma without Mohs surgery at the performance site
* Able to read and understand consent form

Exclusion Criteria:

* None

Where it's running

  • Rochester Dermatologic Surgery
    Victor, New York, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.