Improving HIV PrEP delivery by providers in the U.S.
Official title: From Evidence to Practice for Health Provider Implementation of HIV PrEP in the United States
Funded at University of Rochester · NIH-11470888 · Data updated 2026-11-12
A short-term grant to help doctors, nurses, and other health workers better identify people at risk and prescribe HIV PrEP, and to keep patients using it over time.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 25, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $151,063 |
| NIH project number | 1R03NR022624-01 |
| Project ID | NIH-11470888 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals at risk for HIV who could benefit from starting or continuing PrEP in real-world healthcare settings.
✕Less likely to help
Patients not seeking PrEP or whose clinical care is outside the settings studied may not directly benefit.
What this research studies
This project analyzes how clinics and health systems can implement PrEP more effectively in real-world settings like primary care, women’s health, emergency departments, and pharmacies. It uses existing research methods to understand which strategies work best in different contexts and how payment, workflows, and electronic records affect delivery. The goal is to produce practical, ready-to-use guidance for providers to increase PrEP uptake and long-term adherence. The study builds on prior work to create a clear, context-sensitive toolkit for implementing PrEP. If successful, it could help more people access and stay on PrEP, reducing new HIV infections.
Why it matters
Potential benefit: Patients could benefit from easier access to PrEP and better adherence, lowering their risk of HIV infection.
How similar studies have gone: Previous implementation research has shown promise in identifying effective strategies, but results vary by setting and population; this project aims to synthesize and tailor findings for practical use.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Zhang, Chen — University of Rochester
- Study coordinator: Zhang, Chen
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
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Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
-
TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.