Mobile health exercise program for older adults with myeloid neoplasms
A Pilot Randomized Trial of a Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms
This study is testing a mobile health exercise program to see if it can help older adults with myeloid neoplasms feel better and maintain their physical abilities while they are receiving chemotherapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 170 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | University of Rochester Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Rochester, New York) |
| Trial ID | NCT04981821 on ClinicalTrials.gov |
What this trial studies
This trial evaluates the effectiveness of a mobile health exercise intervention called GO-EXCAP compared to a chemotherapy education control in older patients with myeloid neoplasms undergoing outpatient chemotherapy. The study aims to prevent physical function decline and improve fatigue, mood, and quality of life among participants. Additionally, it will explore the biological effects of the intervention on specific cytokines and gene expression related to health outcomes. The trial will involve 100 older adults, assessing both physical and psychological benefits.
Who should consider this trial
Good fit: Ideal candidates are older adults aged 60 and above with a diagnosis of myeloid neoplasms who are receiving outpatient chemotherapy.
Not a fit: Patients with physical, psychological, or social impairments that hinder their ability to participate in the intervention may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance the physical and mental well-being of older patients undergoing treatment for myeloid neoplasms.
How similar studies have performed: While mobile health interventions have shown promise in other populations, this specific approach for older adults with myeloid neoplasms is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥60 years (conventional definition of older age in clinical trials of MN) * Have a diagnosis of MN * Planned for or receiving outpatient cancer-directed treatments (participants receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll) * English speaking * Eastern Cooperative Oncology Group (ECOG) performance status of 0-3 * No medical contraindications for exercise per oncologist * Able to walk 4 meters as part of Short Physical Performance Battery measured walk (with or without assistive device) * Able to provide informed consent Exclusion Criteria: * Physical, psychological, or social impairments that would interfere with subject's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team
Where this trial is running
Rochester, New York
- University of Rochester Medical Center/Wilmot Cancer Institute — Rochester, New York, United States (Recruiting)
Study contacts
- Principal investigator: Kah Poh Loh — University of Rochester
- Study coordinator: Kah Poh Loh
- Email: kahpoh_loh@urmc.rochester.edu
- Phone: 585-275-5863
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.