Mobile health exercise program for older adults with myeloid neoplasms
Official title: A Pilot Randomized Trial of a Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms
Run by University of Rochester · NCT04981821 · Data updated 2026-11-12
This study is testing a mobile health exercise program to see if it can help older adults with myeloid neoplasms feel better and maintain their physical abilities while they are receiving chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 170 (estimated) |
| Sponsor | University of Rochester Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Rochester, New York) |
| Status | Recruiting |
| Started | January 3, 2022 |
| Main results expected | June 30, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | July 15, 2026 |
| Trial ID | NCT04981821 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are older adults aged 60 and above with a diagnosis of myeloid neoplasms who are receiving outpatient chemotherapy.
✕Probably not a fit
Patients with physical, psychological, or social impairments that hinder their ability to participate in the intervention may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial evaluates the effectiveness of a mobile health exercise intervention called GO-EXCAP compared to a chemotherapy education control in older patients with myeloid neoplasms undergoing outpatient chemotherapy. The study aims to prevent physical function decline and improve fatigue, mood, and quality of life among participants. Additionally, it will explore the biological effects of the intervention on specific cytokines and gene expression related to health outcomes. The trial will involve 100 older adults, assessing both physical and psychological benefits.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance the physical and mental well-being of older patients undergoing treatment for myeloid neoplasms.
How similar studies have gone: While mobile health interventions have shown promise in other populations, this specific approach for older adults with myeloid neoplasms is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥60 years (conventional definition of older age in clinical trials of MN) * Have a diagnosis of MN * Planned for or receiving outpatient cancer-directed treatments (participants receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll) * English speaking * Eastern Cooperative Oncology Group (ECOG) performance status of 0-3 * No medical contraindications for exercise per oncologist * Able to walk 4 meters as part of Short Physical Performance Battery measured walk (with or without assistive device) * Able to provide informed consent Exclusion Criteria: * Physical, psychological, or social impairments that would interfere with subject's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team
Where it's running
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University of Rochester Medical Center/Wilmot Cancer Institute
Rochester, New York, United States Recruiting
Study contacts
- Principal investigator: Kah Poh Loh — University of Rochester
- Study coordinator: Kah Poh Loh
- Email: kahpoh_loh@urmc.rochester.edu
- Phone: 585-275-5863
Similar studies
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This study is creating a detailed registry for people with myeloid neoplasms to gather important information that can help improve treatment and care for these conditions.
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Combining venetoclax with chemotherapy for treating acute myeloid leukemia
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.