NIH-funded research NIH-funded research

ML-ROVER: Reducing Unneeded Lab Tests in Kids with AI

Official title: ML-ROVER: Machine Learning to Reduce Laboratory Test Overutilization

Funded at University of Rochester · NIH-11607116 · Data updated 2026-11-12

Aims to use machine learning to cut unnecessary blood tests in children in intensive care, helping avoid anemia and improve care quality.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startAugust 1, 2024
Project endJuly 31, 2029
Funding year2026
Award (this year)$252,658
NIH project number4R33HS030123-03
Project IDNIH-11607116 on NIH RePORTER

Who could benefit from this research

Could help

Children in intensive care units who routinely undergo laboratory testing may be eligible to participate through data sharing and future CDS integration.

Less likely to help

Patients without ICU lab testing or those not represented in the participating centers may not benefit.

What this research studies

This project uses electronic health records from multiple pediatric centers to develop an ML-based decision-support tool that predicts which routine lab tests may be safely skipped. It focuses on pediatric ICU patients, where blood loss from testing can be harmful. The team plans to design the tool with user-centered principles so clinicians can integrate it smoothly into daily practice. If successful, the approach could guide more judicious testing while maintaining or improving patient safety.

Why it matters

Potential benefit: If successful, it could reduce painful blood draws and iatrogenic anemia while preserving quality of care in pediatric ICUs.

How similar studies have gone: Previous ML-based approaches for predicting lab results exist in adults, but pediatric-focused CDS integration is limited and still early.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Dziorny, Adam C. — University of Rochester
  • Study coordinator: Dziorny, Adam C.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.