Clinical trial Recruiting at 1 site Interventional Ages 9 to 17

Improving HPV vaccination rates through standing orders

Official title: Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

Run by University of Rochester · NCT06380114 · Data updated 2026-11-12

This study tests if allowing healthcare team members to give HPV vaccines without needing a doctor's order can help more kids aged 11-12 get vaccinated.

Quick facts

Study typeInterventional
Ages9 Years to 17 Years
SexAll
Enrollment16000 (estimated)
SponsorUniversity of Rochester
Academic / other
Locations1 site (Rochester, New York)
StatusRecruiting
StartedNovember 4, 2024
Main results expectedMay 2028
Study endsMay 2028
Registry record updatedMay 29, 2026
Trial IDNCT06380114 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adolescents aged 11-17 who are active patients in participating practices.

Probably not a fit

Patients who are already part of practices with high baseline HPV vaccination rates or those with very few eligible 11-12 year-olds may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance HPV vaccination rates among adolescents by implementing standing orders that allow healthcare team members to administer the vaccine without a specific physician's order. It addresses the low vaccination rates in the U.S., particularly among 11-12 year-olds, who are the primary target group for HPV vaccination. The study will also explore how organizational readiness for change influences the effectiveness of these standing orders. By evaluating this approach, the study seeks to provide insights into improving vaccination strategies in healthcare settings.

Why it matters

Potential benefit: If successful, this approach could significantly increase HPV vaccination rates, thereby reducing the incidence of HPV-related cancers.

How similar studies have gone: Previous studies have shown that standing orders can effectively improve vaccination rates in other contexts, suggesting potential success for this novel application.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* active patient in AHP practice

Exclusion Criteria:

* patient belonging to a practice with \>80% UTD baseline HPV vaccination rate for ages 13-17
* patient belonging to a practice with \<20 11-12 year-olds eligible for an HPV dose

Where it's running

  • University of Rochester Medical Center (URMC)
    Rochester, New York, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.