Improving HPV vaccination rates through standing orders

Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

Not applicable Interventional University of Rochester · NCT06380114

This study tests if allowing healthcare team members to give HPV vaccines without needing a doctor's order can help more kids aged 11-12 get vaccinated.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment16000 (estimated)
Ages9 Years to 17 Years
SexAll
SponsorUniversity of Rochester Academic / other
Locations1 site (Rochester, New York)
Trial IDNCT06380114 on ClinicalTrials.gov

What this trial studies

This study aims to enhance HPV vaccination rates among adolescents by implementing standing orders that allow healthcare team members to administer the vaccine without a specific physician's order. It addresses the low vaccination rates in the U.S., particularly among 11-12 year-olds, who are the primary target group for HPV vaccination. The study will also explore how organizational readiness for change influences the effectiveness of these standing orders. By evaluating this approach, the study seeks to provide insights into improving vaccination strategies in healthcare settings.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 11-17 who are active patients in participating practices.

Not a fit: Patients who are already part of practices with high baseline HPV vaccination rates or those with very few eligible 11-12 year-olds may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly increase HPV vaccination rates, thereby reducing the incidence of HPV-related cancers.

How similar studies have performed: Previous studies have shown that standing orders can effectively improve vaccination rates in other contexts, suggesting potential success for this novel application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* active patient in AHP practice

Exclusion Criteria:

* patient belonging to a practice with \>80% UTD baseline HPV vaccination rate for ages 13-17
* patient belonging to a practice with \<20 11-12 year-olds eligible for an HPV dose

Where this trial is running

Rochester, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hpv
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.