Combined mobile exercise and cognitive rehabilitation for older cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-arm pilot refines and tests a multicomponent intervention (E-Co) that integrates mobile health–delivered exercise with cognitive rehabilitation for older adults who completed cancer-directed treatments. Participants aged 60 and older with self-reported concerns about memory or thinking will be enrolled and cleared for exercise by their oncologist. The study will measure feasibility outcomes such as adherence and self-efficacy, along with preliminary cognitive outcomes to see if the combined program produces benefit. Investigators aim to streamline the intervention to make it manageable for older survivors and improve sustained exercise participation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥60 years at the time of consent
* Have a diagnosis of any cancer
* Have completed curative intent treatments

  * Patients on endocrine therapies are allowed to enroll
  * Patients with hematologic malignancies after autologous or allogeneic stem cell transplant are allowed to enroll as long as they have completed curative-intent treatment
* Have concerns about memory or other thinking abilities following cancer treatment\*
* English speaking (because the interventions are available in English language only)
* Eastern Cooperative Oncology Group (ECOG) performance status of 0-3
* No medical contraindications for exercise per oncologist#
* Able to walk 4 meters#
* Able to provide informed consent#

(\*) Confirmed by asking the patient (#) Confirmed through eligibility confirmation with the patient's oncologist or their designee

Exclusion Criteria:

* Physical, psychological, or social impairments that would interfere with patient's ability to participate in the study or participate in the intervention, as determined by the PIs and oncology team.

Where it's running

• University of Rochester
  Rochester, New York, United States Recruiting

Study contacts

• Principal investigator: Kah Poh Loh — University of Rochester
• Study coordinator: Kah Poh Loh
• Email: Kahpoh_Loh@URMC.Rochester.edu
• Phone: 585-276-4353

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.