Sponsor or institution
Clinical trials and research at University of Calgary
As of November 12, 2026, Find a Trial lists 88 clinical trials run by University of Calgary that are recruiting, at sites in 10 countries (most in Canada (88), United States (3), France (3)). By phase: Phase 2 (11), Phase 3 (7), Phase 4 (2), Phase 1 (2). There are also 6 NIH-funded research projects at this institution, with $5.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 88Clinical trials
- 6NIH research projects
- 10Countries
Newest trials
All recruiting trials (88)
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Cerebral oximetry-guided care after cardiac arrest
This study tests whether using a brain oxygen monitor can help guide treatment for adults who have had a cardiac arrest to protect the brain and improve outcomes.
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What helps choking in babies under age two: a look at real-life interventions
This study tests which choking first aid techniques used by bystanders or providers are safest and most effective for infants under two years old in Alberta, Canada.
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Choking interventions in adults and children: what works when someone is blocking the airway
This study observes real-world choking events in Alberta to see which bystander or EMS treatments help people who are over 2 years old.
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Understanding growth hormone deficiency after a brain injury in adults
This observational study tests whether growth hormone deficiency affects quality of life and symptoms in adults with traumatic brain injury and whether GH replacement helps after 12 weeks.
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Intra-arterial Thrombolysis After Endovascular Thrombectomy in AIS
This trial tests whether giving intra-arterial thrombolysis with tenecteplase or alteplase after endovascular thrombectomy helps improve recovery in adults with acute ischemic stroke.
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Impact of a Clinical Information System on hospital outcomes for adults with chronic diseases
This study tests whether implementing a Clinical Information System helps reduce readmissions or death within 30 days after hospital discharge for adults with chronic conditions in Alberta.
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Health, Equity, and Resilience in Girls and Women with ADHD Across the Lifespan
This study tests health and well-being measures in girls and women with and without ADHD across Canada to see how ADHD relates to life phases and experiences.
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Therapeutic cuddling for critically ill children
This project will try therapeutic cuddling to reduce pain, agitation, and delirium in children admitted to the pediatric intensive care unit.
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Split-belt treadmill dosing for early stroke recovery
This program will test how much split-belt treadmill walking with virtual reality people in the first three months after a stroke can safely tolerate.
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Structured robotic gait training with the Trexo walker
This study will test whether a structured Trexo robotic gait training program helps people with neuromotor walking impairments (for example children with cerebral palsy or those with traumatic brain injury) improve walking and reach their therapy goals.
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Custom mandibular oral repositioning device (px3™) to improve sleep quality, heart rate variability, and oxygen levels
This trial tests whether a custom mandibular oral repositioning appliance (px3™) helps healthy adults aged 40–65 with BMI 25–35 sleep better and improve heart-rate variability and nighttime oxygen levels.
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Using ultrasound and protein tests to see who responds to guselkumab for ileal Crohn's disease
This project will try to see if intestinal ultrasound plus blood and tissue protein signatures can show who responds to the medicine guselkumab in adults with ileal Crohn's disease, with or without strictures.
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PROMIS questionnaires and smartphone mobility tracking after sarcoma surgery
This project tests whether PROMIS questionnaires together with a new smartphone app can track recovery and mobility in adults undergoing surgery for sarcoma or giant cell tumor of bone.
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Topical diclofenac gel versus oral ibuprofen for kids with ankle or knee sprains
This trial will try whether diclofenac gel applied to the injured ankle or knee works as well as oral ibuprofen for children aged 6–18 with new sprains or strains.
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Home brain–computer interface program to help children with severe disabilities take part in daily life
This program will try home-based brain–computer interface (BCI) systems to help children aged 5–18 with severe physical or communication disabilities reach personalized life participation goals.
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Ear-based vagus nerve stimulation for chronic whiplash-associated disorder
This study will test whether mild electrical stimulation of the vagus nerve through the ear can help people with chronic whiplash-associated disorder reduce pain and stress-related symptoms.
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RESPONd: remote symptom monitoring and management for cancer patients between ambulatory visits
This project will test whether electronic symptom questionnaires plus nurse follow-up helps cancer patients manage symptoms between clinic visits and improves clinic efficiency.
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Online and in-person exercise programs for cancer survivors in Canada
This study is testing whether online and in-person exercise programs can help cancer survivors in Canada stay active and improve their health.
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Improving iron levels in young female endurance, intermittent, and power/strength athletes aged 16-35
This trial will test whether different types and doses of oral iron supplements, taken every other day for 12 weeks, help young female athletes with low iron stores improve iron levels, gut health, and exercise performance while causing fewer stomach symptoms.
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My Heart and CKD: A Shared Decision Aid to Help CKD and CAD Patients Choose Heart Procedures
A patient-focused online tool tests whether a personalized decision aid can help adults with chronic kidney disease and coronary artery disease make informed choices about heart procedures.
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Brain stimulation for anxiety and depression in children and teens
This program will try transcranial magnetic stimulation (TMS) to see if it reduces anxiety and depression in children and teens aged 6 to 18 who are referred by their doctors.
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Using cilastatin to prevent kidney damage from certain hospital medications
This trial will test whether cilastatin can prevent acute kidney injury in hospitalized adults receiving certain kidney-harming medications.
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Using genetic information to guide antidepressant prescribing for teens with anxiety and depression
This study is testing if using genetic information to choose antidepressants helps teens aged 12-17 with anxiety and depression feel better compared to regular prescribing methods.
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See if the psychedelic experience matters for psilocybin’s effects
This study tests whether blocking the acute subjective effects of psilocybin changes its short- and longer-term outcomes in healthy adults.
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Psilocybin-assisted therapy for ongoing symptoms after concussion
This study will see if a single higher dose of psilocybin combined with Acceptance and Commitment Therapy helps adults (18–65) with persistent post-concussion symptoms reduce their symptom burden compared to a very low-dose control.
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Virtual home hospital care with remote monitoring for acute kidney injury
This study is testing whether virtual care and remote monitoring can help adults with acute kidney injury recover better at home and avoid going back to the hospital.
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Postpartum aspirin to prevent blood clots after delivery
A 3rd-phase trial tests whether taking a small daily dose of aspirin for 6 weeks after giving birth works as well as usual preventive injections of LMWH to reduce blood clots in people with pregnancy-related clotting risk.
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Evaluating the effects of a single session of robotic gait training with Trexo
This study is testing how a single session of robotic walking training with the Trexo device can help people with physical disabilities, like cerebral palsy, improve their walking ability and overall activity.
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Wellness program for organ transplant patients
This study tests a wellness program that helps kidney and liver transplant patients improve their health and well-being through exercise, nutrition, stress management, and sleep support before and after surgery.
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Improving sleep to prevent depression and anxiety in at-risk adolescents
This study is testing if a short therapy for sleep problems can help prevent depression and anxiety in teens aged 12 to 18 who are at risk because of their family history.
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Improving pain control after cesarean section with nerve blocks
This study is testing if a special pain relief method called TAP blocks can help women feel less pain and recover faster after having a cesarean section.
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Comparing different doses of tenecteplase for treating acute ischemic stroke
This study is testing whether a standard dose or a lower dose of a medication called tenecteplase can help people who have had an acute ischemic stroke recover better and stay safe.
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Cannabis-derived THC vs CBD in people with multiple sclerosis
This study tests whether THC or CBD pills affect thinking skills and bladder symptoms in people with MS.
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Using intravenous fluids to prevent pancreatitis after ERCP procedures
This study tests if different types of intravenous fluids can help prevent pancreatitis in patients undergoing ERCP procedures.
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Identifying genetic factors affecting ADHD treatment response
This study is trying to find out if certain genes affect how well kids and young adults with ADHD respond to a common medication called methylphenidate.
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Using donor milk to improve gut health in cesarean-born infants
This study is trying to see if giving cesarean-born babies donor human milk instead of formula can help their gut health and improve sleep and growth.
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Using Patient-Reported Outcomes in Routine Cardiac Care for Coronary Artery Disease
This study tests whether using the APPROACH ePROM surveys and Clinician Report with patients who have coronary artery disease, to see if it can be done in routine care and be acceptable to patients and their doctors.
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Comparing Ketorolac and Morphine for Pain Relief in Children with Appendicitis
This study is testing if ketorolac can help relieve pain just as well as morphine in children aged 6-17 who might have appendicitis.
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Creating a database for patients with bronchiectasis and NTM in Canada
This study is creating a database to gather information from adults with bronchiectasis and NTM to help improve care and understanding of these conditions.
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Comparing biopsy results to surgical samples in thyroid cancer
This study is testing if the results from small needle biopsies of thyroid cancer match up with those from larger surgical samples to help doctors make better treatment decisions for patients with papillary thyroid cancer.
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Using brain stimulation and medication to help young people with suicidal thoughts
This study is testing if a combination of brain stimulation and a medication can help young adults aged 18-24 who have serious thoughts of suicide feel better.
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Using psilocybin with therapy to help reduce heavy drinking in people with alcohol use disorder
This study is testing if a single dose of psilocybin, along with therapy, can help people with alcohol use disorder drink less over 12 weeks.
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Evaluating the best first-line treatment for moderate-to-severe Crohn's disease
This study is testing which of three approved treatments works best to help people with moderate-to-severe Crohn's disease feel better and stay off steroids for a year.
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High salt diet for treating Postural Orthostatic Tachycardia Syndrome
This study tests if a high salt diet can help people with Postural Orthostatic Tachycardia Syndrome feel better by improving their symptoms and blood volume.
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Testing IV saline for cognitive function in POTS and Long COVID patients
This study is testing whether IV saline can help improve brain fog and mental fatigue in people with POTS and Long COVID.
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Using a CO2 rebreather to improve blood pressure in patients with neurogenic orthostatic hypotension
This study is testing whether a CO2 rebreather can help people with neurogenic orthostatic hypotension improve their blood pressure and feel better when standing up.
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Electronic decision aid for stroke prevention in atrial fibrillation
This study is testing a new electronic tool to help people with atrial fibrillation make better choices about stroke prevention treatments before their doctor visits.
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Comparing tilt tests and ECG recordings for diagnosing unexplained fainting in older adults
This study is testing whether doing a tilt test first helps doctors diagnose the cause of fainting better and faster in older adults compared to using a heart monitor first.
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Oral blood thinners for preventing blood clots after hip fractures
This study is testing if oral blood thinners can help prevent blood clots in people aged 50 and older who have had hip fractures and need surgery.
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Botulinum injections for anterolateral lower-leg chronic exertional compartment syndrome
This will test whether botulinum toxin injections into the lower-leg muscles reduce exercise-related pain in adults with anterolateral CECS.
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Evaluating anticoagulation management during pregnancy and postpartum
This study is trying to see how well anticoagulation management works for pregnant people using a specific medication to help prevent blood clots during and after pregnancy.
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Using Ondansetron to Prevent Fainting Episodes
This study is testing if the medication ondansetron can help adults who frequently faint feel better and prevent future fainting spells.
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Balloon dilation procedure for treating Eustachian tube dysfunction
This study is testing if a balloon dilation procedure can help people with Eustachian tube dysfunction feel better compared to a fake treatment.
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Rapid, accurate, low-cost blood test to help diagnose concussion
This study will test if a portable biosensor can accurately measure a blood biomarker (GFAP) to help diagnose concussion in adults who come to the emergency department.
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Investigating hormone therapy effects on heart and kidney health
This study is trying to see how different ways of taking estrogen and testosterone affect heart and kidney health in both cisgender and transgender people.
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Using a fecal test to reduce unnecessary colonoscopies after polyp removal
This study is testing whether a simple stool test can help people with a history of polyps or family history of colorectal cancer avoid unnecessary colonoscopies.
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Program to support Indigenous women in improving health through physical activity
This study is testing a program that helps Indigenous women improve their health through education and physical activity while also sharing cultural knowledge and building community support.
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App to teach safe fitting and use of canes, crutches, and walkers
This test will see if an app helps adults who regularly use canes, crutches, or walkers learn to fit and use their walking aids more safely.
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Yoga program for young adults with cancer
This study tests a yoga program for young adults with cancer to see if it can help improve their physical and mental well-being.
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Breathing carbon dioxide to help with low blood pressure when standing
This study tests if breathing in carbon dioxide can help people with Neurogenic Orthostatic Hypotension feel better and manage their blood pressure when standing.
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Improving care for moderate and late preterm infants in Alberta NICUs
This study is testing a new way to improve care for babies born a bit early in Alberta's NICUs to see if it helps them go home sooner.
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High volume fluid treatment for children with E. coli infection
This study is testing if giving children with a serious E. coli infection more fluids through an IV can help prevent kidney problems and other complications.
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Assessing IV fluids to prevent pancreatitis after ERCP
This study is testing if giving patients the right amount of IV fluids before and after a procedure can help prevent pancreatitis after an ERCP.
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Using Atomoxetine to Prevent Fainting Spells
This study is testing whether a daily medication called Atomoxetine can help adults who often faint feel better and improve their quality of life.
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Improving evaluation and management of patients with suspected bile duct stones
This study is testing a new way to improve how doctors check for and treat patients who might have stones in their bile duct.
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Using prebiotics to improve glycemic control in type 1 diabetes
This study is testing whether taking prebiotics can help people with type 1 diabetes better manage their blood sugar levels while they continue their insulin therapy.
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Online physical activity program for children and adolescents with cancer
This study tests an online exercise program for kids and teens with cancer to see if it helps them feel better during their treatment.
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Using Probenecid to Help with Opioid Withdrawal Symptoms
This study is testing if probenecid can help adults with chronic pain feel better as they reduce their use of opioid medications and deal with withdrawal symptoms.
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Using compression garments to help manage POTS symptoms
This study tests if wearing waist-high and abdominal compression garments can help adults with POTS feel better and manage their symptoms in everyday life.
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Online parenting support program for families facing stressors
This study is testing an online version of a parenting support program to help families facing stress from issues like depression and domestic violence, especially during COVID-19.
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Trying new brain stimulation to help ADHD symptoms
This study tests whether theta burst repetitive transcranial magnetic stimulation (rTMS) to the right prefrontal cortex can reduce ADHD symptoms in children aged 9–15.
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Exercise programs for cancer survivors in rural areas
This study is testing community and online exercise programs for cancer survivors in rural areas to see if they can help improve their quality of life and encourage long-term fitness habits.
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Sleep health of assisted-living residents
This project tries to see if sleep quality is linked with physical activity, functional ability, and memory in older adults living in assisted-living facilities.
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Understanding how heart rate affects blood flow in the brain
This study is testing how changes in heart rate affect blood flow to the brain in patients with postural tachycardia syndrome to help improve their symptoms and quality of life.
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Observing outcomes of perilunate injuries in Canada
This study is looking at how perilunate injuries are treated in Canada to see what happens to patients over time and improve care for these injuries.
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Registry for cardiovascular imaging in Canada
This study is trying to gather information from patients with heart problems to see if certain tests can help predict their health risks over time.
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Assessing heart function and circulation in adults
This study is testing new ways to check heart function and blood flow in adults with heart failure compared to healthy people to see how their hearts respond during a handgrip test.
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Effects of CO2 on heart rate and symptoms in POTS patients
This study tests if breathing in higher levels of carbon dioxide can help improve heart rate and symptoms for people with Postural Orthostatic Tachycardia Syndrome (POTS).
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Registry for patients undergoing advanced endoscopy procedures
This study is collecting information from adults who are having a special procedure called ERCP to help doctors understand how well it works for treating pancreatic and biliary diseases.
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Oral aspirin around the time of endovascular coiling for unruptured brain aneurysms
This trial tests whether taking 325 mg of aspirin for 5 days around the time of coiling helps prevent strokes compared with a placebo in people with unruptured brain aneurysms.
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Comparing Propranolol and Ivabradine for treating POTS
This study tests which medication, Propranolol or Ivabradine, works better to help people with Postural Tachycardia Syndrome feel better and manage their symptoms.
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Cannabidiol (CBD) to prevent chronic migraine
This trial will test whether a daily cannabidiol (CBD) pill can reduce headaches in adults with chronic migraine.
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Identifying genetic factors in children affected by antidepressant side effects
This study is trying to find out if certain genes can help predict which children might have negative side effects from antidepressants, so doctors can better manage their treatment.
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Assessing how heart rate affects blood flow in patients with pacemakers
This study tests how changing heart rates affect blood flow in patients with pacemakers to see if it helps manage fainting spells.
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How changes in brain blood flow affect breathing during sleep
This project will test whether temporarily lowering blood flow to the brain changes how healthy adults' breathing responds to low oxygen and high carbon dioxide during normal sleep and short periods of low oxygen.
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Nonmyeloablative stem cell transplant for children with sickle cell disease and incompatible donors
This study is testing a new way to do a stem cell transplant for children with sickle cell disease who have a donor that doesn't perfectly match to see if it can help them get better.
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Aerobic exercise for older adults at increased risk of Alzheimer's and related dementias
This tests whether regular aerobic exercise, compared with stretching and strength sessions, can improve memory and brain blood flow in inactive adults aged 50–80 who have memory complaints and vascular risk factors.
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Investigating antibodies in patients with Postural Tachycardia Syndrome
This study is testing if people with Postural Tachycardia Syndrome have more specific antibodies in their blood compared to healthy individuals, which could help us understand the condition better.
NIH-funded research (6)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Hyperhydration to protect kidneys in children with Shiga toxin E. coli infection
A multinational study will test whether giving extra fluids early can reduce kidney injury and serious complications in children with Shiga toxin–producing E. coli infection.
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Multiple sclerosis as a disease caused by protein misfolding
A Canadian research project is exploring whether MS starts with misfolded proteins that damage myelin and then trigger autoimmunity, using mouse models and human brain samples.
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Early high-volume IV fluids to protect children's kidneys after E. coli infection
Giving extra IV fluids early to children with Shiga toxin–producing E. coli infection to help prevent kidney damage.
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Investigating the risks of chronic wasting disease transmission to humans
This study is looking into chronic wasting disease, which affects deer and elk, to see if it could be a risk to humans by testing it on monkeys and mice, so we can better understand if it might pose any health threats to people in the future.
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Investigating how misfolded proteins contribute to multiple sclerosis
This study is looking into how misfolded proteins might be causing multiple sclerosis and how they affect brain health, with the hope of finding new treatments that could help people with MS.
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Using increased fluid intake to improve kidney health in children with E. coli infections
This study is looking at whether giving kids more fluids early on when they have infections from a type of E. coli can help protect their kidneys and prevent serious problems, and it’s for children who are dealing with these infections.
Quick answers
How many clinical trials run by University of Calgary are recruiting right now?
88, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 10 countries. The most sites are in Canada (88 trials), United States (3 trials), France (3 trials), Australia (2 trials), Denmark (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 11, Phase 3: 7, Phase 4: 2, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.