Using compression garments to help manage POTS symptoms
Official title: Compression Garments in the Community With POTS
Run by University of Calgary · NCT04881318 · Data updated 2026-11-12
This study tests if wearing waist-high and abdominal compression garments can help adults with POTS feel better and manage their symptoms in everyday life.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | University of Calgary Academic / other |
| Locations | 1 site (Calgary, Alberta) |
| Status | Recruiting |
| Started | May 17, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | May 7, 2026 |
| Trial ID | NCT04881318 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults diagnosed with POTS who reside in Canada and own waist-high compression garments.
✕Probably not a fit
Patients with overt causes for postural tachycardia or severe anxiety symptoms may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of commercially available waist-high and abdominal compression garments in adults diagnosed with Postural Orthostatic Tachycardia Syndrome (POTS) in a community setting. Participants will wear these garments in their daily lives to assess improvements in heart rate and symptom reduction. The study builds on previous laboratory findings that indicated potential benefits of compression garments for POTS patients. An optional sub-study will also explore the effectiveness of abdominal compression garments.
Why it matters
Potential benefit: If successful, this study could provide a non-pharmacological treatment option that significantly improves the quality of life for POTS patients.
How similar studies have gone: Previous studies have shown promise for compression garments in acute settings, but this approach in a community setting is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Physician diagnosis of Postural Tachycardia Syndrome (POTS) * Resident of Canada * Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg, 30-40 mmHg) * Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts) * Able to participate in a 4-day study (2x2 day segments with a 5-day washout period) Exclusion Criteria: * Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis * Not a resident of Canada * Participants with somatization or severe anxiety symptoms will be excluded * Pregnant (self-reported) * Inability to tolerate compression garments for the duration of the study * Does not own a waist-high compression garment * Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies
Where it's running
-
University of Calgary
Calgary, Alberta, Canada Recruiting
Study contacts
- Principal investigator: Satish M Raj, MD MSCI — University of Calgary
- Study coordinator: Kate M Bourne, BSc
- Email: autonomic.research@ucalgary.ca
- Phone: 403-210-7401
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.