Clinical trial Recruiting at 1 site Observational Ages 18 and up

Assessing IV fluids to prevent pancreatitis after ERCP

Official title: Association Between Peri-procedural Intravenous Hydration and Post- Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Run by University of Calgary · NCT05211206 · Data updated 2026-11-12

This study is testing if giving patients the right amount of IV fluids before and after a procedure can help prevent pancreatitis after an ERCP.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment13000 (estimated)
SponsorUniversity of Calgary
Academic / other
Locations1 site (Calgary, Alberta)
StatusRecruiting
StartedJanuary 10, 2022
Main results expectedDecember 31, 2026
Study endsJune 30, 2027
Registry record updatedApril 29, 2026
Trial IDNCT05211206 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 years or older who are referred for ERCP and can provide informed consent.

Probably not a fit

Patients with contraindications to ERCP or those unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between peri-procedural intravenous fluid administration and the risk of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. It aims to evaluate short-term aggressive hydration regimens that are practical for outpatient settings, focusing on fluid type, volume, and timing. By analyzing these factors, the study seeks to identify effective strategies to reduce the incidence of post-ERCP pancreatitis, which is a significant adverse event associated with the procedure.

Why it matters

Potential benefit: If successful, this study could lead to improved protocols for IV fluid administration that significantly reduce the risk of pancreatitis after ERCP, enhancing patient safety and outcomes.

How similar studies have gone: Previous studies have shown that aggressive hydration can reduce the risk of post-ERCP pancreatitis, but this study's specific approach to short-term hydration regimens is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subject referred for ERCP, regardless of indication;
* Subject age 18 years or older;
* Subject able to give informed consent to involvement be included.

Exclusion Criteria:

* Subject has a standard contraindication to ERCP;
* Subject or surrogate unable or unwilling to provide informed consent;
* Subject age \< 18 years.

Where it's running

  • Peter Lougheed Hospital
    Calgary, Alberta, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.