Clinical trial Recruiting at 3 sites Interventional Ages 18 and up

RESPONd: remote symptom monitoring and management for cancer patients between ambulatory visits

Official title: Implementing REmote SymPtom mOnitoring and maNagement (RESPONd): Evaluating the Impact on Cancer Patients, System Efficiency, and Economic Outcomes

Run by University of Calgary · NCT07024329 · Data updated 2026-11-12

This project will test whether electronic symptom questionnaires plus nurse follow-up helps cancer patients manage symptoms between clinic visits and improves clinic efficiency.

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Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1055 (estimated)
SponsorUniversity of Calgary
Academic / other
Locations4 sites (Calgary, Alberta and 3 other locations)
StatusRecruiting
StartedMay 16, 2025
Main results expectedNovember 30, 2026
Study endsMarch 31, 2027
Registry record updatedApril 30, 2026
Trial IDNCT07024329 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with cancer receiving care at one of the participating Alberta clinics who can register for MyAHS Connect, have regular phone access, an internet-capable device, and can complete electronic PROs in English without clinic support.

Probably not a fit

Patients who live outside Alberta, lack regular phone or internet/device access, have cognitive impairment preventing reliable self-reporting, or cannot use MyAHS Connect or English are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

RESPONd implements digitally enabled remote symptom monitoring across six tertiary, regional, and community cancer clinics using a stepped-wedge rollout over 1.5 years. Enrolled adults complete electronic patient-reported outcome (PRO) questionnaires at home (weekly on active treatment or monthly on follow-up), and study nurses monitor responses and contact patients to provide tailored support. Collected PRO data are used in weekly clinic triage huddles to guide care and improve coordination. The study measures patient outcomes, healthcare use (including emergency visits), and clinic workflow efficiencies while collecting participant experience feedback.

Why it matters

Potential benefit: If successful, RESPONd could reduce emergency visits and improve quality of life by identifying and managing symptoms earlier.

How similar studies have gone: Previous oncology studies of routine electronic PRO monitoring have shown reductions in emergency visits and improvements in quality of life and survival, though real-world implementation across diverse clinics has been less widely tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18
* Have cancer
* Receiving care in one of the participating clinics.
* Able to sign up for MyAHS Connect and consent.
* Have access to a digital device at home
* Able to complete their electronic PROs questionnaire without support from the clinic team on a weekly (patients on active treatment) or monthly (patients on follow-up) basis, for the duration of the intervention or until they are discharged from the clinic.
* Regular access to a telephone in order for the study nurse to call patients to provide symptom management support.

Exclusion Criteria:

* Patients with cognitive disabilities or who cannot reliably report symptoms independently.
* Patients not residing in Alberta, as government-issued ID is required to register for MyAHS Connect.
* Patients who do not have regular access to a telephone, as the study nurse needs to be able to call patients to provide symptom management support.
* Patients who do not speak English, or who do not have an English-speaking friend, family member, or caregiver to assist them, as the electronic PROs questionnaire is only available in English at this time.

Where it's running

  • Arthur J. E. Child Comprehensive Cancer Centre
    Calgary, Alberta, Canada
    Recruiting
  • Cross Cancer Institute
    Edmonton, Alberta, Canada
    Recruiting
  • Central Alberta Cancer Centre
    Red Deer, Alberta, Canada
    Recruiting
  • High River Community Cancer Centre
    High River, Alberta, Canada
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.