RESPONd: remote symptom monitoring and management for cancer patients between ambulatory visits
Official title: Implementing REmote SymPtom mOnitoring and maNagement (RESPONd): Evaluating the Impact on Cancer Patients, System Efficiency, and Economic Outcomes
Run by University of Calgary · NCT07024329 · Data updated 2026-11-12
This project will test whether electronic symptom questionnaires plus nurse follow-up helps cancer patients manage symptoms between clinic visits and improves clinic efficiency.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1055 (estimated) |
| Sponsor | University of Calgary Academic / other |
| Locations | 4 sites (Calgary, Alberta and 3 other locations) |
| Status | Recruiting |
| Started | May 16, 2025 |
| Main results expected | November 30, 2026 |
| Study ends | March 31, 2027 |
| Registry record updated | April 30, 2026 |
| Trial ID | NCT07024329 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with cancer receiving care at one of the participating Alberta clinics who can register for MyAHS Connect, have regular phone access, an internet-capable device, and can complete electronic PROs in English without clinic support.
✕Probably not a fit
Patients who live outside Alberta, lack regular phone or internet/device access, have cognitive impairment preventing reliable self-reporting, or cannot use MyAHS Connect or English are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
RESPONd implements digitally enabled remote symptom monitoring across six tertiary, regional, and community cancer clinics using a stepped-wedge rollout over 1.5 years. Enrolled adults complete electronic patient-reported outcome (PRO) questionnaires at home (weekly on active treatment or monthly on follow-up), and study nurses monitor responses and contact patients to provide tailored support. Collected PRO data are used in weekly clinic triage huddles to guide care and improve coordination. The study measures patient outcomes, healthcare use (including emergency visits), and clinic workflow efficiencies while collecting participant experience feedback.
Why it matters
Potential benefit: If successful, RESPONd could reduce emergency visits and improve quality of life by identifying and managing symptoms earlier.
How similar studies have gone: Previous oncology studies of routine electronic PRO monitoring have shown reductions in emergency visits and improvements in quality of life and survival, though real-world implementation across diverse clinics has been less widely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 * Have cancer * Receiving care in one of the participating clinics. * Able to sign up for MyAHS Connect and consent. * Have access to a digital device at home * Able to complete their electronic PROs questionnaire without support from the clinic team on a weekly (patients on active treatment) or monthly (patients on follow-up) basis, for the duration of the intervention or until they are discharged from the clinic. * Regular access to a telephone in order for the study nurse to call patients to provide symptom management support. Exclusion Criteria: * Patients with cognitive disabilities or who cannot reliably report symptoms independently. * Patients not residing in Alberta, as government-issued ID is required to register for MyAHS Connect. * Patients who do not have regular access to a telephone, as the study nurse needs to be able to call patients to provide symptom management support. * Patients who do not speak English, or who do not have an English-speaking friend, family member, or caregiver to assist them, as the electronic PROs questionnaire is only available in English at this time.
Where it's running
-
Arthur J. E. Child Comprehensive Cancer Centre
Calgary, Alberta, Canada Recruiting -
Cross Cancer Institute
Edmonton, Alberta, Canada Recruiting -
Central Alberta Cancer Centre
Red Deer, Alberta, Canada Recruiting -
High River Community Cancer Centre
High River, Alberta, Canada Not yet recruiting
Study contacts
- Principal investigator: Linda Watson, RN, PhD — Cancer Care Alberta, Alberta Health Services
- Study coordinator: Chizoba Anyimukwu, MPH, DrPH
- Email: chizoba.anyimukwu@albertahealthservices.ca
- Phone: 587-943-3556
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.