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Clinical trials and research at Erasmus Medical Center

• 121Clinical trials
• 4NIH research projects
• 1New in 30 days
• 18Countries

Newest trials

All recruiting trials (121)

• SYMmetric Valve expansion to reduce hypoattenuated leaflet thickening after balloon-expandable TAVI

  This trial tests whether the Double-TAP post-dilatation strategy can reduce HALT and improve valve function in patients 70 or older undergoing balloon-expandable TAVI.

  Recruiting Erasmus Medical Center · Düsseldorf and 4 other locations · NCT07872020

• External warming to help septic patients without fever

  We’re testing whether warming the body externally can help people with sepsis who don’t have a fever.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07831057

• Personalized AI Education Avatar for cancer treatment information

  A digital avatar using AI-delivered educational videos helps adults starting new cancer treatments learn about their plan and side effects, with patient-friendly guidance and nurse support as needed.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07715981

• Turbine-based CO2 Insufflator in Pediatric Laparoscopy

  A new turbine-powered CO2 insufflator is being tested in children to see if it can maintain steadier abdominal pressures during laparoscopic surgery.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07715968

• Guideline Adherence in HFrEF: See If Mirror Information Helps Doctors and Patients Follow GDMT

  This study tests whether showing doctors, or both doctors and patients, mirror information about how well guideline-directed medical therapy is being used in heart failure with reduced ejection fraction.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07702760

• Mild heat therapy added to standard treatment for locally advanced head and neck cancer

  This early-stage trial tests whether mild hyperthermia can be safely added to standard radiotherapy with or without chemotherapy for locally advanced head and neck cancer.

  Recruiting Phase 1 Erasmus Medical Center · Rotterdam, South Holland · NCT07690618

• Corticosteroid injections added to standard care for chronic midportion Achilles tendinopathy

  This trial tests whether 1–3 ultrasound-guided corticosteroid injections added to standard care help adults with long-standing midportion Achilles tendinopathy more than placebo injections plus standard care.

  Recruiting Phase 3 Erasmus Medical Center · Rotterdam · NCT07650396

• Understanding how often and why a patient’s breathing and the ventilator don’t stay in sync

  This study tests how often patient-ventilator asynchrony occurs in mechanically ventilated adults and how it relates to their health and outcomes.

  Recruiting at 2 sites Erasmus Medical Center · Eindhoven, North Brabant and 2 other locations · NCT07624786

• Higher radiation dose to the tumor to avoid surgery in rectal cancer

  Aims to see if giving a higher dose of radiation to the tumor can help people with non-locally advanced rectal cancer keep their rectum without needing surgery.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07616297

• HoorToren program to prevent noise-induced hearing loss in primary school children

  This project will test whether the HoorToren classroom program helps 10–11-year-old Dutch children and their parents adopt safer headphone listening habits to reduce noise-related hearing damage.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07513077

• Patient-tailored 3D-printed ARCHITECT applicator for cervical cancer brachytherapy

  We’re testing a 3D-printed, one-time use ARCHITECT applicator to see if it safely helps deliver brachytherapy for locally advanced cervical cancer.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07435987

• Adaptive high-precision radiation for abdominopelvic lymph node oligometastases

  This trial will try giving adapted high-dose, fewer-session targeted radiation (online adaptive SBRT) to adults with up to five abdominal or pelvic lymph node metastases to shorten treatment time while protecting nearby organs.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07415356

• CBCT-guided markerless stereotactic radiotherapy for kidney cancer

  This project tests whether using CBCT imaging with breath-hold or surface-guided gating can deliver markerless SBRT more precisely for adults with non-metastatic kidney cancer.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07402109

• Cyclosporine versus methotrexate for children with alopecia areata

  This project tests whether cyclosporine or methotrexate works better as the first systemic treatment for children and teens (ages 2–17) with moderate-to-severe alopecia areata.

  Recruiting Phase 4 Erasmus Medical Center · Rotterdam · NCT07381556

• Natural history of CAMK2-related synaptopathies

  This project will map how symptoms develop over time in children and adults who have a pathogenic CAMK2 gene variant to identify patterns and useful outcome measures.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07372833

• Intravenous iron infusion after transcatheter aortic valve implantation for people with iron deficiency

  This trial will test whether an intravenous iron infusion after TAVI helps people aged 65 and older with severe aortic stenosis and iron deficiency feel better and walk farther.

  Recruiting Phase 4 Erasmus Medical Center · Rotterdam, South Holland · NCT07370688

• A standardized outcome set to measure results of dental implants (DENS).

  This project will test a short patient questionnaire (DENS) to see if it captures outcomes that matter to adults getting dental implants.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07337057

• Detecting tumor DNA in small automated capillary blood samples from adults with colorectal cancer liver metastases.

  This project will try whether tiny automated capillary (finger‑prick) blood samples can detect circulating tumor DNA in adults with colorectal cancer that has spread to the liver.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07310537

• Unravelling the Measles Paradox

  This project will test whether natural measles causes lasting 'immune amnesia' by changing circulating immune memory cells in adults who are vaccinated, recently infected, or had measles in the past.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07267585

• Building a short video and audio database of cancer pain to help AI recognize patient pain

  This project collects short face and voice recordings from adults with cancer who do and don't have pain to help test AI that tries to recognize pain from expressions.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07262632

• Shorter apalutamide or enzalutamide treatment for low-volume, hormone-sensitive metastatic prostate cancer

  This study will see if stopping apalutamide or enzalutamide after 12 months (and restarting only if PSA rises) works as well as continuing the drug for men with low-volume, hormone-sensitive metastatic prostate cancer.

  Recruiting at 21 sites Phase 3 Erasmus Medical Center · Alkmaar and 25 other locations · NCT07260435

• More Representative Vaginal Temperature Measurements During Hyperthermia Treatments for Gynaecologic Cancer

  This study tests whether a pelotte provides more representative vaginal temperature readings during hyperthermia treatment for gynecologic cancer than a standard vaginal probe in women receiving radiotherapy.

  Recruiting Erasmus Medical Center · Rotterdam, South Holand · NCT07235540

• ctDNA-guided adjuvant chemotherapy for high-risk rectal cancer

  We’re testing whether giving adjuvant chemotherapy after surgery helps prevent recurrence in rectal cancer patients who still have ctDNA detected after their operation.

  Recruiting at 20 sites Phase 3 Erasmus Medical Center · 's-Hertogenbosch and 24 other locations · NCT07188025

• Breast reconstruction choices after mastectomy when radiotherapy is planned

  This nationwide prospective effort will compare reconstruction types and timing to see if certain approaches give better satisfaction, fewer complications, and lower costs for adults having mastectomy plus radiotherapy.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07178886

• Preoperative Lymph Node Assessment in Cholangiocarcinoma using Endoscopic Ultrasound

  This study tests how well preoperative endoscopic ultrasound (EUS) finds lymph node metastases in adults with presumed resectable or certain unresectable cholangiocarcinomas to see if surgery should proceed.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland and 5 other locations · NCT07161869

• Tracking respiratory viruses in healthcare and animal workers

  This project will test whether regular virus checks and immune monitoring in healthcare and animal workers can find new or spreading respiratory viruses early.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07156890

• Combination intraperitoneal and systemic therapy for gastric cancer with peritoneal metastases

  This phase 2 trial tests a new combination treatment for adults with gastric cancer that has spread to the lining of the abdomen, using intraperitoneal irinotecan with standard systemic therapy and biomarker-guided addition of nivolumab or trastuzumab when appropriate.

  Recruiting at 3 sites Phase 2 Erasmus Medical Center · Amsterdam and 2 other locations · NCT07133490

• APTw-CEST MRI to detect glioblastoma progression after radiotherapy

  This study tests whether a special MRI method called APTw-CEST can tell adults with glioblastoma who have had radiotherapy or chemoradiotherapy whether new MRI changes mean true tumor growth or just treatment-related pseudoprogression.

  Recruiting at 3 sites Erasmus Medical Center · Amsterdam and 3 other locations · NCT07121842

• Lycopene to track dietary compliance in healthy men

  This tests whether a single 40 mg dose of lycopene from a supplement or from tomato soup raises blood lycopene in healthy men so it can be used to track diet compliance.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07117110

• How the CES1 liver enzyme affects capecitabine levels in people with colorectal, gastric, or esophageal cancer

  This project will see if differences in the CES1 enzyme change how capecitabine is processed and whether that affects side effects like hand‑foot syndrome in adults starting capecitabine with oxaliplatin for colorectal, gastric, or esophageal cancer.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07114627

• Rapid bedside fibrinogen testing for bleeding trauma patients in the emergency department

  This will test a rapid bedside fibrinogen test for adults with traumatic bleeding to help decide who needs fibrinogen replacement.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07097337

• Translesional pressure measurements to see whether a mesenteric artery narrowing causes symptoms.

  This study will test whether measuring the pressure across a narrowed mesenteric artery helps identify which adults with chronic mesenteric ischemia who are scheduled for endovascular treatment will benefit from treatment.

  Recruiting at 2 sites Erasmus Medical Center · Enschede, Overijssel and 2 other locations · NCT07059520

• Using SCALE-EYE to measure colorectal polyp size accurately and reduce procedure waste

  This trial tests whether SCALE-EYE can accurately measure polyp size during screening or surveillance colonoscopy in people aged 55–80 and whether its use can cut down on follow-up procedures and waste.

  Recruiting at 3 sites Erasmus Medical Center · Eindhoven, North Brabant and 2 other locations · NCT07005453

• Blood test for early detection of colorectal cancer

  This study is testing a new blood test to see if it can find colorectal cancer early in people with Lynch Syndrome, who are at higher risk for this disease.

  Recruiting Erasmus Medical Center · Leiden, South Holland and 1 other locations · NCT06989814

• Ketogenic diet therapy for patients with acromegaly

  This study tests whether a ketogenic diet can help people with acromegaly lower their growth hormone levels and improve their quality of life compared to a Mediterranean diet.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06949891

• Registry of long-term outcomes for children after cardiac arrest

  This study is looking at the long-term health and recovery of children in the Netherlands who have had a cardiac arrest to see how well they do after treatment.

  Recruiting at 7 sites Erasmus Medical Center · Nijmegen, Gelderland and 6 other locations · NCT06938009

• Virtual Ward to Enable Earlier Hospital Discharge

  This project tests whether eligible hospitalized adults can go home sooner and be safely cared for through a Virtual Ward using remote vital-sign monitoring, home diagnostics, and telemedicine support.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06936891

• AWARE.HIV Europe: supporting hospital teams to find undiagnosed HIV across Europe

  This project will test whether putting dedicated HIV teams into hospitals increases HIV testing for people who come in with conditions that could suggest HIV across ten European countries.

  Recruiting at 27 sites Erasmus Medical Center · Ghent and 27 other locations · NCT06900829

• Direct chemotherapy delivery to the liver for bile duct cancer patients

  This study is testing if delivering chemotherapy directly to the liver can help adults with bile duct cancer live longer and feel better after surgery.

  Recruiting Phase 2 Erasmus Medical Center · Rotterdam, South Holland · NCT06888063

• Home monitoring for patients with pulmonary fibrosis

  This study tests if using home monitoring and video calls can help people with pulmonary fibrosis manage their condition as well as or better than regular clinic visits.

  Recruiting at 11 sites Erasmus Medical Center · Amsterdam and 10 other locations · NCT06883448

• Testing diuretics to predict kidney disease progression

  This study is testing if using diuretics can help predict how quickly chronic kidney disease gets worse in patients.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06841692

• Playing music during ECT to reduce agitation afterward

  This trial will try playing recorded music during ECT to see if it reduces agitation after the treatment in adults receiving ECT for severe depression.

  Recruiting at 2 sites Erasmus Medical Center · Rotterdam and 1 other locations · NCT06817330

• Home-based prehabilitation program for liver transplant patients

  This study tests a home-based program that helps liver transplant patients get stronger and healthier before surgery to see if it improves their recovery and reduces complications.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06808945

• High-flow oxygen therapy for patients weaning off mechanical ventilation

  This study tests if high-flow oxygen therapy can help patients with tracheostomies breathe easier and clear mucus better while they are transitioning off mechanical ventilation.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06776939

• High intensity interval training for patients with congenital heart defects

  This study is testing if a 12-week home workout program can help young people with certain heart defects exercise better and feel stronger.

  Recruiting Erasmus Medical Center · Nijmegen, Gelderland and 1 other locations · NCT06771687

• Using higher doses of beta-lactam antibiotics for critically ill patients with sepsis

  This study is testing if giving critically ill patients with sepsis a higher dose of beta-lactam antibiotics can help them recover better and live longer compared to the standard dose.

  Recruiting Phase 4 Erasmus Medical Center · Rotterdam · NCT06766461

• Registry for understanding chronic subdural hematoma

  This study is looking to gather information from adults with chronic subdural hematoma to see how different treatments work and improve care for future patients.

  Recruiting at 2 sites Erasmus Medical Center · Amsterdam and 1 other locations · NCT06759428

• Investigating the timing of intubation in COVID-19 patients with respiratory failure

  This study is trying to see if intubating COVID-19 patients earlier or later can lead to better health outcomes and lower risks of lung injury.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06757166

• Using AI to Enhance Family Communication in Intensive Care

  This study is testing if using AI can help doctors in the ICU communicate better with families of patients by making it easier to summarize important conversations.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland and 1 other locations · NCT06756542

• Skipping full lymph node removal for stage III melanoma patients who show a strong response in the index node

  This trial will see if patients with resectable stage III melanoma who get neoadjuvant ipilimumab plus nivolumab and show a major pathological response in the index lymph node can safely avoid therapeutic lymph node dissection.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06754904

• Home-based computerized cognitive rehabilitation for people with acquired brain injury

  This trial will try an online RehaCom cognitive training program at home to help people with acquired brain injury in outpatient rehabilitation improve attention and memory.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06749197

• Testing urine biomarkers for chronic kidney disease progression

  This study is testing a new urine test to see if it can better predict how chronic kidney disease will progress in people with stage 3 CKD.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06732349

• Validation of a quality of life assessment for spina bifida in Dutch

  This study is testing a new questionnaire in Dutch to see how spina bifida affects the quality of life for children, teens, and adults with the condition compared to those without it.

  Recruiting Erasmus Medical Center · Groningen and 1 other locations · NCT06723951

• Capsule-sponge surveillance for ultralong-segment Barrett's esophagus

  This tests whether the EndoSign capsule-sponge can detect precancerous changes and early esophageal cancer in adults with ultralong-segment Barrett's esophagus compared with standard endoscopy.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06720636

• Smartwatch monitoring of vital signs during chemotherapy

  This will try using a Fitbit smartwatch to see if it can detect changes in vital signs in adults with stomach or esophageal cancer during chemotherapy.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06680778

• Effects of intermittent fasting on the blood microbiome

  This study is testing how intermittent fasting might change the bacteria in the blood of healthy people to see if it can improve liver health.

  Recruiting at 2 sites Erasmus Medical Center · Lanzhou, Gansu and 1 other locations · NCT06678516

• Using PET-CT to find unknown primary cancer sources

  This study is testing a new imaging method to help find the original source of cancer in adults who have been diagnosed with carcinoma of unknown primary origin.

  Recruiting at 6 sites Erasmus Medical Center · Amsterdam and 5 other locations · NCT06644716

• Personalized app for melanoma survivorship care

  This study is testing a new app designed to help people with stage I and II melanoma manage their care better and feel more empowered compared to those who receive standard care.

  Recruiting at 3 sites Erasmus Medical Center · Dordrecht, South Holland and 3 other locations · NCT06643286

• Using virtual reality to prepare lung transplant patients for ICU admission

  This study tests if using virtual reality can help lung transplant patients feel more prepared and less anxious about their upcoming stay in the ICU.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06642636

• Intraoperative neuronal recordings during brain tumor surgery

  This study tries out a Neuropixel probe to record brain activity during awake tumor removal in adults with glioma or brain metastases to explore how neurons interact with tumors.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06617208

• Home-based follow-up for colorectal cancer patients after surgery

  This study is testing a home-based follow-up program for colorectal cancer patients after surgery to see if it can improve their quality of life and reduce stress compared to regular hospital visits.

  Recruiting at 2 sites Erasmus Medical Center · Breda, North Brabant and 4 other locations · NCT06613581

• Evaluating the GAAD score's effectiveness in detecting liver cancer in patients with chronic liver disease.

  This study is testing if the GAAD score can help find liver cancer earlier in people with chronic liver disease who need regular check-ups.

  Recruiting Erasmus Medical Center · Rotterdam, CA · NCT06601231

• Comparing two ventilation methods in patients with asthma and COPD

  This study is testing whether a new way of helping people with asthma or COPD breathe on a ventilator can reduce breathing problems compared to a standard method.

  Recruiting at 2 sites Erasmus Medical Center · Rotterdam, South Holland and 1 other locations · NCT06563544

• Evaluating a cancer admission score for emergency department patients

  This study is testing a new scoring system to see if it can help doctors better predict what will happen to cancer patients who come to the emergency room, while also trying out a way to speed up their care if they score high.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06558487

• Using spinal cord stimulation to treat painful mononeuropathy

  This study is testing whether spinal cord stimulation can help people with painful nerve issues who haven't found relief from other treatments.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06546371

• Image-guided treatment for vaginal cancer

  This study is testing if using image-guided treatment can improve the results and quality of life for patients with vaginal cancer receiving radiation therapy.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06514235

• Improving cardiac rehabilitation by addressing sleep and stress

  This study is testing whether adding a program that helps improve sleep and reduce stress to regular heart rehab can help people with heart problems feel better overall.

  Recruiting at 3 sites Erasmus Medical Center · Eindhoven, North Brabant and 2 other locations · NCT06505109

• Using radiation therapy after chemotherapy for inoperable bile duct cancer

  This study is testing if adding a special type of radiation therapy after chemotherapy can help people with inoperable bile duct cancer live longer and feel better.

  Recruiting at 6 sites Erasmus Medical Center · Wilrijk, Antwerp and 7 other locations · NCT06493734

• Developing reference values for the Muscle Power Sprint Test in children

  This study is trying to find out how fast kids aged 5-12 can sprint short distances to help set new standards for their physical fitness.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06448520

• Tailored nutritional follow-up after discharge for children from term birth to 18 years

  This trial tests whether a personalized nutrition follow-up program after hospital discharge helps children who started nutritional support and their families see better nutrition, feeding behavior, and quality of life.

  Recruiting at 6 sites Erasmus Medical Center · Rotterdam, South Holland and 5 other locations · NCT06414200

• New self-expandable metal stent to relieve malignant esophageal strictures

  This test will try a new self-expandable metal stent to relieve swallowing problems in adults with incurable esophageal cancer.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06364553

• Using FAPI PET-CT to Improve Treatment for Proximal Cholangiocarcinoma

  This study is testing if a new type of imaging called FAPI PET-CT can help doctors better plan treatment for patients with bile duct cancer by finding cancer spread more accurately than regular scans.

  Recruiting at 2 sites Phase 2/3 Erasmus Medical Center · Amsterdam and 2 other locations · NCT06355427

• Using an online tool for advance care planning in cancer patients

  This study is testing an online tool to help cancer patients plan their future care and make sure their wishes are respected during treatment.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06350968

• Improving gastric cancer diagnosis using cell-free DNA analysis

  This study is testing whether analyzing cell-free DNA from fluid in the abdomen can help doctors better detect advanced gastric cancer in patients and improve their treatment options.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06308510

• Using AI to improve diagnosis and recurrence prediction in thymic tumors

  This study is testing if artificial intelligence can help doctors better diagnose thymic tumors and predict the chances of them coming back for patients with these rare cancers.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06301945

• Using fluorescent imaging agents to improve tumor removal during surgery

  This study is testing a new way to help surgeons see and remove all of the cancer during surgery by using special fluorescent dyes that highlight tumor tissue.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06292845

• Comparing surgery and best treatment for recurrent glioblastoma

  This study is testing whether surgery or the best available treatment helps people with recurring glioblastoma feel better and live longer.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06283927

• Registry for systemic treatments of alopecia areata

  This study is trying to see how well different systemic treatments work for people with moderate-to-severe alopecia areata, alopecia totalis, and alopecia universalis.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06283316

• Resection techniques for recurrent glioblastoma

  This study is testing different methods of mapping the brain during surgery for recurring glioblastoma to see which one helps patients keep their movement and speech abilities while removing as much of the tumor as possible.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06273176

• Collecting data on prostate cancer patients treated with Lu-PSMA therapy

  This study is trying to learn more about how well Lu-PSMA therapy works for men with advanced prostate cancer by collecting data and blood samples from patients receiving the treatment.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06260410

• Using bright light therapy to help reduce depressive symptoms in adults with intellectual disabilities

  This study tests if bright light therapy can help reduce depression in adults with intellectual disabilities and improve their quality of life.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06215235

• Selecting Advanced Breast Cancer Patients for Talazoparib Treatment Using the RECAP Test

  This study is testing if a new test can help find advanced breast cancer patients who will benefit from a specific treatment called talazoparib.

  Recruiting at 3 sites Phase 2 Erasmus Medical Center · Leiden, South Holland and 2 other locations · NCT06193525

• Using advanced MRI to improve radiotherapy for glioblastoma

  This study is testing whether using advanced MRI techniques can help doctors better target glioblastoma tumors during radiotherapy, aiming to protect healthy tissue while effectively treating the cancer.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06183983

• Intensive pre-surgery treatment for lymph node–positive esophageal and esophagogastric junction adenocarcinoma

  This study tests whether giving both FLOT chemotherapy and CROSS chemoradiation before surgery, in different orders, helps people with node-positive esophageal or esophagogastric junction adenocarcinoma live longer without the cancer coming back.

  Recruiting Phase 2 Erasmus Medical Center · Eindhoven, North Brabant and 9 other locations · NCT06161818

• Comparing palliative care and surgery for high-grade glioma patients

  This study is testing whether palliative care or surgery helps people with high-grade glioma live longer and feel better.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06146738

• Comparing tumor resection and biopsy for high-grade glioma patients

  This study is testing whether removing a brain tumor or just taking a small sample helps older patients with high-grade gliomas live longer and feel better afterward.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06146725

• Guided growth treatment for hip issues in children with cerebral palsy

  This study is testing a new way to help children with cerebral palsy grow their hips properly to prevent dislocations and reduce the need for major surgeries.

  Recruiting at 3 sites Erasmus Medical Center · Amsterdam and 4 other locations · NCT06118736

• Comparing two surgical approaches for high-grade glioma patients

  This study is testing whether a more extensive surgical method for removing high-grade brain tumors helps patients live longer and feel better compared to a standard approach.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06118723

• Evaluating the need for dexamethasone during paclitaxel chemotherapy

  This study is testing if skipping dexamethasone before paclitaxel chemotherapy is just as safe and effective for adults with solid tumors as using it.

  Recruiting Phase 4 Erasmus Medical Center · Rotterdam, South Holland · NCT06118710

• Detecting azole resistance in invasive aspergillosis patients using blood samples

  This study is testing a new way to quickly find out if patients with a serious fungal infection have a type that is resistant to common treatments, using blood samples from people with weakened immune systems.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06069505

• Comparing treatment options for children with trigonocephaly

  This study is trying to see if treating children with trigonocephaly without surgery is just as effective as surgery in helping them grow and develop well.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06069479

• Multidisciplinary aftercare program for patients with acquired brain injury

  This study tests a new aftercare program for people with acquired brain injuries to see if it helps them stay active and improve their quality of life after rehab.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06058351

• Adjuvant Gardasil 9 Vaccination for Women Treated for Vulvar HSIL

  This study tests whether giving Gardasil 9 after treatment for vulvar HSIL can help prevent recurrence in women 18 and older.

  Recruiting Phase 4 Erasmus Medical Center · Rotterdam · NCT06052696

• Test to predict pregnancy chances for IVF patients

  This study is testing a new way to predict the chances of getting pregnant through IVF by looking at the vaginal bacteria in women aged 18 to 43.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06051201

• Reducing invasive tests for patients with blood in urine

  This study is testing a new urine test to see if it can help people with blood in their urine avoid unnecessary invasive procedures while still checking for serious conditions like bladder cancer.

  Recruiting Erasmus Medical Center · Rotterdam · NCT06026189

• Ultrasound renal denervation for uncontrolled high blood pressure after kidney transplant

  This study will try ultrasound renal denervation on the native kidneys to see if it lowers blood pressure in kidney transplant patients whose hypertension is not controlled by medicines.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05934383

• Effects of left ventricular unloading during VA ECMO support

  This study is testing whether using an intra-aortic balloon pump along with VA ECMO support can help patients with heart failure recover better than just using VA ECMO alone.

  Recruiting at 7 sites Erasmus Medical Center · Bruges and 13 other locations · NCT05913622

• Standardizing care for hepatitis delta in the Netherlands

  This study is trying to gather information from adults with hepatitis delta to better understand the disease and improve how it's treated.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05903742

• Improving birth outcomes through lifestyle changes before and during early pregnancy

  This study is testing whether helping women improve their lifestyle, nutrition, and stress management before and during early pregnancy can lead to better birth outcomes for both mothers and babies.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05870878

• Combining olaparib with PRRT for advanced gastroenteropancreatic neuroendocrine tumors

  This trial will test whether giving the oral PARP blocker olaparib together with PRRT helps adults with advanced, well-differentiated gastroenteropancreatic neuroendocrine tumors that progressed after prior PRRT.

  Recruiting Phase 1 Erasmus Medical Center · Rotterdam, South Holland · NCT05870423

• Combining Docetaxel or Cabazitaxel with Darolutamide for Advanced Prostate Cancer

  This study is testing if adding darolutamide to chemotherapy drugs docetaxel or cabazitaxel can help men with advanced prostate cancer feel better and improve their treatment results.

  Recruiting Phase 2 Erasmus Medical Center · Rotterdam · NCT05762536

• Fluorescence-guided surgery to help remove laryngeal and hypopharyngeal cancers

  This trial tests a fluorescent imaging agent to help see cancer tissue during laryngeal and hypopharyngeal cancer surgery in adults.

  Recruiting Phase 2 Erasmus Medical Center · Rotterdam, South Holland and 1 other locations · NCT05752149

• Helping find chronic mesenteric ischemia earlier

  This project tests whether a 13C-butyrate breath test combined with CT-based mesenteric artery calcium scoring can help diagnose adults with suspected chronic mesenteric ischemia.

  Recruiting at 2 sites Erasmus Medical Center · Enschede, Overijssel and 3 other locations · NCT05735002

• Comparing surgery to watchful waiting for asymptomatic congenital pulmonary airway malformation in children

  This study is testing whether surgery or just keeping an eye on children with asymptomatic congenital pulmonary airway malformation works better for their health and quality of life.

  Recruiting Erasmus Medical Center · Nijmegen, Gelderlanf and 1 other locations · NCT05701514

• Combination therapy for autoimmune hypothyroidism

  This study is testing if adding a medication called liothyronine to the standard treatment for autoimmune hypothyroidism can help people who still feel tired even when their thyroid levels are normal.

  Recruiting at 16 sites Phase 3 Erasmus Medical Center · Almere Stad and 18 other locations · NCT05682482

• Home-based follow-up for testicular cancer patients

  This study tests if a home-based follow-up for people who have recently finished treatment for testicular cancer can help them feel better and less anxious compared to regular hospital visits.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT05670938

• Collagen matrix or palatal graft versus natural healing for preserving the front-tooth ridge

  This follow-up will see if using a collagen matrix or a palatal connective tissue graft with a bone xenograft helps preserve gum and bone around a single front-tooth implant better than letting the socket heal on its own in people who had early implant placement.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05663385

• Stopping nivolumab early for melanoma treatment

  This study is testing if stopping nivolumab early is safe and effective for patients with advanced melanoma who have responded well to their initial treatment.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05652673

• Chemotherapy followed by immunotherapy for advanced bladder cancer

  This study is testing if giving chemotherapy followed by an immunotherapy called avelumab can help people with advanced bladder cancer before they have surgery to remove the tumor.

  Recruiting at 4 sites Phase 2 Erasmus Medical Center · Nijmegen, Gelderland and 3 other locations · NCT05600127

• Comparing techniques for preserving liver grafts from deceased donors

  This study is testing three different ways to keep liver donations from deceased donors in good shape to see if any of them can improve their quality and help more patients receive successful transplants.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT05327478

• Dendritic cell therapy combined with surgery for mesothelioma treatment

  This study is testing if adding a special vaccine made from immune cells to surgery can help adults with a type of lung cancer called mesothelioma feel better after their initial treatment.

  Recruiting Phase 1 Erasmus Medical Center · Rotterdam, South Holland · NCT05304208

• Evaluating complete revascularization in patients with multivessel coronary artery disease

  This study is testing if a specific heart procedure can improve health outcomes for people with multiple blocked arteries who experience chest pain or other heart issues.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT05230446

• Collecting blood samples from lung cancer patients on targeted therapy

  This study is collecting blood samples from adults with non-small cell lung cancer who are on targeted therapy to see how their treatment is working and to check for any changes in their cancer.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05221372

• Investigating the HIV Infected Reservoir to Find a Cure

  This study is trying to find ways to cure HIV by looking at the hidden virus in the blood of different groups of people living with HIV.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05215704

• Active surveillance for oesophageal cancer after chemoradiotherapy

  This study is testing whether closely monitoring patients with locally advanced oesophageal cancer after they finish chemoradiotherapy can be a safe and effective alternative to immediate surgery.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT04886635

• Comparing balloon and self-expanding valves for heart valve replacement

  This study is testing whether balloon-expandable or self-expanding heart valves work better for older patients needing a replacement due to a failed heart valve.

  Recruiting at 8 sites Erasmus Medical Center · Los Angeles, California and 13 other locations · NCT04843072

• Using engineered T cells to treat melanoma and head and neck cancer

  This study is testing a new treatment using specially engineered T cells to see if they can help people with advanced melanoma and head-and-neck cancer.

  Recruiting Phase 1/2 Erasmus Medical Center · Rotterdam · NCT04729543

• Observing the health management of patients with rare genetic syndromes

  This study looks at how patients with rare genetic syndromes like Prader-Willi and Klinefelter manage their health as they move from children's care to adult care to see what support they need.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT04463316

• Doxapram treatment for preterm infants with breathing issues

  This study is testing if doxapram can help preterm infants with breathing problems avoid serious complications and reduce the need for breathing machines.

  Recruiting at 18 sites Phase 3 Erasmus Medical Center · Brussels, Avenaue Hippocrate 10 and 23 other locations · NCT04430790

• Comparing awake craniotomy and general anesthesia for glioblastoma surgery

  This study is testing whether having brain surgery while awake is safer and more effective than having it under general anesthesia for people with glioblastoma in important areas of the brain.

  Recruiting at 5 sites Erasmus Medical Center · Ghent and 4 other locations · NCT03861299

• Observing the safety and effectiveness of treatments for children with inflammatory bowel disease

  This study looks at how safe and effective current treatments are for children under 18 with inflammatory bowel disease to help understand their outcomes and any risks involved.

  Recruiting at 2 sites Erasmus Medical Center · Rotterdam and 1 other locations · NCT03571373

NIH-funded research (4)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Molecular detection of MBL and better risk prediction through immune and protein profiling

  This research aims to use blood DNA sequencing plus immune protein information to detect early B-cell changes that can lead to CLL, helping adults over 40 understand their risk.

  NIH research Erasmus Medical Center · Rotterdam, NETHERLANDS · NIH-11453390

• Understanding how bird flu viruses switch to highly dangerous forms

  Researchers are studying how bird flu viruses change to become highly dangerous in poultry to help prevent outbreaks that harm animals and people.

  NIH research Erasmus Medical Center · Rotterdam, NETHERLANDS · NIH-11418524

• Understanding how bird flu viruses become highly dangerous

  This study looks at how certain bird viruses can change and become more dangerous, which is important for keeping both birds and people safe from illness, and it aims to help us understand and stop future outbreaks.

  NIH research Erasmus Medical Center · Rotterdam, NETHERLANDS · NIH-10896206

• Understanding why some patients fail treatment with dolutegravir for HIV

  This study is looking into why some people with HIV in Brazil aren't responding to the medication dolutegravir, by checking for certain changes in the virus that might be causing this issue, so we can find better ways to help everyone manage their treatment.

  NIH research Erasmus Medical Center · Rotterdam, NETHERLANDS · NIH-10694925

Quick answers

How many clinical trials run by Erasmus Medical Center are recruiting right now?

121, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in Netherlands (121 trials), Belgium (10 trials), Germany (8 trials), Switzerland (6 trials), United States (6 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 3: 5, Phase 4: 5, Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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