Lycopene to track dietary compliance in healthy men

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This crossover pilot enrolls ten healthy men aged 18–75 who each receive a single 40 mg oral dose of lycopene as a supplement tablet and, on a separate occasion, an equivalent amount in cooked tomato soup. Blood samples are taken one hour before and at 1, 3, 6, 12, 24, 48 and 72 hours after each intervention to measure plasma lycopene concentrations. Participants complete a food frequency questionnaire and keep a food diary to document habitual intake and intake during the intervention. The study examines whether the single-dose plasma response is consistent and large enough to serve as a practical compliance marker for dietary lycopene intake.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male;
* Healthy;
* 18-75 yrs old.

Exclusion Criteria:

* Allergic for tomatoes;
* Any gastrointestinal disorder within 3 months prior to the intervention;
* Recent medication or supplement use;
* Recent substantial change in weight;
* Adherence to a specific diet ( for example the Moorman-diet);
* Using recreational drugs more than once a month;
* Smoking and excessive alcohol consumption (\>10 standardized glasses a week).
* Risk of a dependency situation with the researchers.

Where it's running

• Erasmus MC
  Rotterdam, Netherlands Recruiting

Study contacts

• Principal investigator: Lionne DF Venderbos — Erasmus Medical Center
• Study coordinator: Lionne DF Venderbos
• Email: l.venderbos@erasmusmc.nl
• Phone: 0031650001668

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.