Building a short video and audio database of cancer pain to help AI recognize patient pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-centre project at the Erasmus MC Cancer Institute will collect short (up to 60 seconds) video and audio recordings of adults with active cancer in two groups: patients admitted for cancer-related pain and controls admitted for chemotherapy with no pain. Participants will read a neutral prompt and, when relevant, briefly describe their pain while also completing a short questionnaire and allowing researchers to extract clinical data such as pain scores, medications, and tumour type. Recordings and linked clinical data will be securely stored under GDPR-compliant procedures and used to extract facial and vocal features with open-source tools like OpenFace and OpenSmile. The resulting labeled multimodal database is intended to support future development and testing of AI-based automatic pain recognition tools.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (≥18 years)
* Diagnosed with cancer, active
* Able to communicate verbally in Dutch or English
* Able to provide written informed consent.
* Pain group specific:
* Experiencing pain related to cancer
* Admitted to the hospital due to pain
* Control group specific:
* Not experiencing pain (NRS = 0)
* Admitted to the hospital for chemotherapy

Exclusion Criteria:

* Cognitive, physical, or medical limitations that prevent participation in the audiovisual recording sessions or affect facial expressions or voice (e.g. facial paralysis, tracheostomy, severe speech impairment).
* Critical illness or end-of-life care where participation would impose an additional burden.
* Experiencing pain not associated with cancer
* Infectious isolation precautions that prevent safe data collection

Where it's running

• Erasmus University Medical Centre
  Rotterdam, South Holland, Netherlands Recruiting

Study contacts

• Principal investigator: Mark Mulder, dr.ir. — Erasmus University Medical Centre
• Study coordinator: Marsha Kamsteeg, MSc
• Email: m.kamsteeg@erasmusmc.nl
• Phone: +31 107040704

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.