Evaluating a cancer admission score for emergency department patients
Official title: The Internal Prospective validatiON of a prediCtiOn Model for the Change of admIssion for Patient With caNcer Admitted to the emerGency Department (ONCOMING Study)
Run by Erasmus Medical Center · NCT06558487 · Data updated 2026-11-12
This study is testing a new scoring system to see if it can help doctors better predict what will happen to cancer patients who come to the emergency room, while also trying out a way to speed up their care if they score high.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Erasmus Medical Center Academic / other |
| Locations | 1 site (Rotterdam, South Holland) |
| Status | Recruiting |
| Started | December 2, 2024 |
| Main results expected | December 1, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | August 15, 2025 |
| Trial ID | NCT06558487 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults with solid or hematological malignancies who are currently receiving or have recently received systemic therapy and are presenting to the emergency department.
✕Probably not a fit
Patients under 18 years old or those who have only undergone surgical treatment for cancer may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the accuracy of the Cancer Admission Score (CAS) in predicting the disposition of patients with active cancer who visit the emergency department. It involves calculating the CAS after triage and after initial blood results, comparing predicted outcomes with actual patient dispositions. Additionally, an early bed reservation intervention will be tested for patients with a high CAS score to improve care efficiency. The study will also track metrics such as length of stay and time-to-disposition.
Why it matters
Potential benefit: If successful, this study could enhance emergency care for cancer patients by improving the accuracy of admission predictions and optimizing resource allocation.
How similar studies have gone: While the CAS model is being evaluated in this context, similar predictive models in emergency care have shown promise, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with solid or hematological malignancies and receiving systemic therapy or having received systemic therapy within the last 3 months. * Presented at or admitted from the emergency department for the oncology, hematology neuro- or lung-oncology clinical unit. Exclusion Criteria: * \<18 years old * Only received a surgical intervention as cancer treatment * Admitted to the ED for the surgical department
Where it's running
-
Erasmus University Medical Center
Rotterdam, South Holland, Netherlands Recruiting
Study contacts
- Principal investigator: Jason den Duijn — Erasmus Medical Center
- Study coordinator: Jason den Duijn
- Email: j.denduijn@erasmusmc.nl
- Phone: 0107040704
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.