Home-based prehabilitation program for liver transplant patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the feasibility and effectiveness of a multimodal home-based prehabilitation program for patients awaiting liver transplantation. The program lasts eight weeks and includes physical exercise, nutritional support, smoking cessation, and psychological counseling. The primary goal is to assess how well patients can engage with this program, while secondary objectives focus on improvements in surgical outcomes such as reduced complications and faster recovery. The study will be conducted at the Erasmus Medical Center in Rotterdam, Netherlands.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years,
* Anticipated waitlisting for LT,
* Speaks the Dutch language,
* Understands the purpose of the study and has given written informed consent.

Exclusion Criteria:

* Experienced a major adverse cardiovascular event in the past six months,
* Experienced a cerebrovascular incident in the past six months,
* Medical history of an uncontrolled heart rhythm disorder,
* Hepatic encephalopathy grade 3 or 4,
* Acute liver failure,
* Acute-on-chronic liver failure,
* Hospitalization at start of the study.
* Non-treated esophageal varices (i.e., no previous variceal eradication endoscopy or adequately dosed NSBB)

Where it's running

• Erasmus Medical Center
  Rotterdam, Netherlands Recruiting

Study contacts

• Study coordinator: Lysanne P.M. Beuk
• Email: l.p.m.beuk@erasmusmc.nl
• Phone: +31615822753

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.