Test to predict pregnancy chances for IVF patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The ReceptIVFity test evaluates the vaginal microbiome to predict the success rate of IVF or IVF-ICSI treatments. This prospective, non-invasive randomized controlled study aims to compare Shared Decision Making with Physician Decision in determining the likelihood of successful pregnancies. It includes an observational arm for women of non-European origin and focuses on naïve IVF patients aged 18 to 43. The study seeks to reduce unnecessary treatment cycles and improve the efficacy of IVF procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Naïve IVF or IVF/ICSI patients
2. Indication for an IVF or IVF-ICSI procedure.
3. 18 years \< age \< 43 years.
4. Willing to provide a vaginal swab with the ReceptIVFity test.
5. Willing to provide informed consent.

Exclusion Criteria:

1. The use of hormonal contraceptives at the time of taking the test.
2. The use of antibiotic treatment at the time of taking the test.
3. Emergency IVF for cancer or other reasons.
4. Women with endometriosis pre-treated with an Gn-RH analogue.
5. Women having IVF for egg preservation reasons.

Where it's running

• Erasmus University Medical Center
  Rotterdam, Netherlands Recruiting

Study contacts

• Principal investigator: Sam Schoenmakers, Dr. drs. — Erasmus MC Rotterdam
• Study coordinator: Xu Shan Gao, drs.
• Email: guvastudie@erasmusmc.nl
• Phone: +31631016348

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.