Observing the health management of patients with rare genetic syndromes

GROWing Up With Rare GENEtic Syndromes ….When Children With Complex Genetic Syndromes Reach Adult Age

Observational Erasmus Medical Center · NCT04463316

This study looks at how patients with rare genetic syndromes like Prader-Willi and Klinefelter manage their health as they move from children's care to adult care to see what support they need.

Quick facts

Study typeObservational
Enrollment600 (estimated)
Ages18 Years and up
SexAll
SponsorErasmus Medical Center Academic / other
Locations1 site (Rotterdam, South Holland)
Trial IDNCT04463316 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients with rare genetic syndromes, such as Prader-Willi Syndrome and Klinefelter Syndrome, who receive multidisciplinary care at a specialized outpatient clinic. The study aims to assess the complexities of managing these syndromes as patients transition from pediatric to adult care, highlighting the need for coordinated health management to address ongoing medical issues. By analyzing patient files, the study seeks to improve understanding of the long-term care needs of individuals with these conditions.

Who should consider this trial

Good fit: Ideal candidates include patients with rare genetic syndromes attending the multidisciplinary outpatient clinic at Erasmus Medical Center.

Not a fit: Patients with common genetic disorders or those not receiving care at the specified clinic may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the quality of care and health outcomes for adults with rare genetic syndromes.

How similar studies have performed: While there may be limited studies focusing specifically on adult care for these syndromes, the approach of multidisciplinary management has shown promise in related fields.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with rare syndromes or rare congenital diseases visiting the multidisciplinary outpatient clinic for patients with rare diseases at the department of endocrinology, internal medicine, Erasmus Medical Center.

Exclusion Criteria:

* None

Where this trial is running

Rotterdam, South Holland

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prader-Willi SyndromePWS-like SyndromeSilver Russel SyndromeCongenital HypopituitarismKlinefelterSyndromeCongenital Adrenal HyperplasiaXXXXY SyndromeXXYY Syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.