Registry of long-term outcomes for children after cardiac arrest
Official title: Pediatric Resuscitation Neuroprognostication and Outcomes Registry
Run by Erasmus Medical Center · NCT06938009 · Data updated 2026-11-12
This study is looking at the long-term health and recovery of children in the Netherlands who have had a cardiac arrest to see how well they do after treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 24 Hours to 18 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Erasmus Medical Center Academic / other |
| Locations | 7 sites (Nijmegen, Gelderland and 6 other locations) |
| Status | Recruiting |
| Started | June 14, 2023 |
| Main results expected | January 2030 |
| Study ends | January 2030 |
| Registry record updated | April 22, 2025 |
| Trial ID | NCT06938009 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children under 18 years old who have experienced cardiac arrest and received treatment in one of the participating academic hospitals in the Netherlands.
✕Probably not a fit
Patients who are neonates younger than 24 hours old or those who experienced cardiac arrest in a neonatal intensive care unit may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry aims to gather data on the long-term outcomes of children in the Netherlands who experience cardiac arrest, whether in or out of the hospital. It will analyze survival rates, neurological outcomes, and the impact of emergency and post-resuscitation care on recovery. The study will collect routine medical records and follow patients through standard outpatient visits without requiring additional procedures. Data will be collected longitudinally at specified intervals to assess functional and neuropsychological outcomes over time.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better long-term outcomes for children who experience cardiac arrest.
How similar studies have gone: Other studies have shown success in similar observational approaches, but this specific registry focuses on pediatric cardiac arrest outcomes, making it a novel initiative.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients under the age of 18 * Experienced in-hospital or out-of-hospital cardiac arrest in the Netherlands * Attended by emergency medical services or admitted to one of the seven participating Dutch academic pediatric hospitals * Cardiac arrest defined as absence of palpable pulse or need for chest compressions lasting ≥1 minute * Arrest managed under European Resuscitation Council guidelines (BLS/APLS) Exclusion Criteria: * Cardiac arrest occurring in neonates younger than 24 hours of age * Cardiac arrest occurring in a neonatal intensive care unit (NICU) setting
Where it's running
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Radboud umc
Nijmegen, Gelderland, Netherlands Recruiting -
Mumc
Maastricht, Limburg, Netherlands Recruiting -
Amsterdam UMC
Amsterdam, North Holland, Netherlands Recruiting -
Umcg
Groningen, Provincie Groningen, Netherlands Recruiting -
Lumc
Leiden, South Holland, Netherlands Recruiting -
Erasmus MC
Rotterdam, South Holland, Netherlands Recruiting
Show 1 more location
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Umcu
Utrecht, Utrecht, Netherlands Recruiting
Study contacts
- Principal investigator: Corinne Buysse, MD PhD — Erasmus Medical Center
- Study coordinator: Gabry De Jong
- Email: gabry.dejong@erasmusmc.nl
- Phone: 0031107040704
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.