Comparing treatment options for children with trigonocephaly

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to evaluate the effectiveness of conservative treatment compared to surgical intervention in children aged 0 to 8 years with trigonocephaly. The study will assess clinical outcomes, psychosocial wellbeing, parental stress, and associated costs over time. Participants will be monitored for head growth, cognitive and behavioral development, and quality of life, with data collected at multiple points from birth to age 8. The hypothesis is that conservative treatment is non-inferior to surgery in terms of clinical outcomes and cost-effectiveness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosis of trigonocephaly

Exclusion Criteria:

* metopic ridge (physiologic early closure of metopic suture)

Where it's running

• Erasmus MC
  Rotterdam, Netherlands Recruiting

Study contacts

• Principal investigator: Irene MJ Mathijssen, MD, PhD, MBA-H — Erasmus Medical Center
• Study coordinator: Irene MJ Mathijssen, MD, PhD, MBA-H
• Email: i.mathijssen@erasmusmc.nl
• Phone: +31655758441

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• SYMmetric Valve expansion to reduce hypoattenuated leaflet thickening after balloon-expandable TAVI

  This trial tests whether the Double-TAP post-dilatation strategy can reduce HALT and improve valve function in patients 70 or older undergoing balloon-expandable TAVI.

  Recruiting Erasmus Medical Center · Düsseldorf and 4 other locations · NCT07872020

• External warming to help septic patients without fever

  We’re testing whether warming the body externally can help people with sepsis who don’t have a fever.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07831057

• Personalized AI Education Avatar for cancer treatment information

  A digital avatar using AI-delivered educational videos helps adults starting new cancer treatments learn about their plan and side effects, with patient-friendly guidance and nurse support as needed.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07715981

• Turbine-based CO2 Insufflator in Pediatric Laparoscopy

  A new turbine-powered CO2 insufflator is being tested in children to see if it can maintain steadier abdominal pressures during laparoscopic surgery.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT07715968

• Guideline Adherence in HFrEF: See If Mirror Information Helps Doctors and Patients Follow GDMT

  This study tests whether showing doctors, or both doctors and patients, mirror information about how well guideline-directed medical therapy is being used in heart failure with reduced ejection fraction.

  Recruiting Erasmus Medical Center · Rotterdam · NCT07702760

• Mild heat therapy added to standard treatment for locally advanced head and neck cancer

  This early-stage trial tests whether mild hyperthermia can be safely added to standard radiotherapy with or without chemotherapy for locally advanced head and neck cancer.

  Recruiting Phase 1 Erasmus Medical Center · Rotterdam, South Holland · NCT07690618

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.