Sponsor or institution
Clinical trials and research at Centre hospitalier de l'Université de Montréal (CHUM)
As of November 12, 2026, Find a Trial lists 72 clinical trials run by Centre hospitalier de l'Université de Montréal (CHUM) that are recruiting, at sites in 10 countries (most in Canada (72), United States (2), France (2)). By phase: Phase 2 (12), Phase 4 (3), Phase 1/2 (3), Phase 3 (3). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 72Clinical trials
- 10Countries
Newest trials
All recruiting trials (72)
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Laser-based sizing of GI lesions during endoscopies
This study tests whether the AccuMeasure laser tool gives more accurate and reliable lesion size measurements during colonoscopies for adults with colon polyps or Crohn’s disease than traditional endoscopic estimates.
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Restrictive fluid strategy with phlebotomy during liver transplantation
This study tests whether a restrictive fluid plan with phlebotomy during liver transplant helps patients recover better than a more fluid-intensive plan.
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Mobile app to help adults in Quebec use cannabis more safely
A mobile app is being tested to see if it helps adults who use cannabis non-medically in Quebec use cannabis more safely.
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Adaptive external beam radiotherapy added to Lutetium-177 PSMA therapy for metastatic castration-resistant prostate cancer
This trial tests whether adding targeted external beam radiotherapy during Lutetium-177 PSMA treatment can improve outcomes for men with metastatic castration‑resistant prostate cancer.
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Methionine-restricted diet and gut microbiota
We will test whether a methionine-restricted diet changes gut bacteria and inflammation in healthy adults aged 20–50.
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KAN-004 treatment for immune-related diarrhea and colitis
This trial is testing whether KAN-004 is safe and tolerable for adults who develop moderate-to-severe diarrhea or colitis after treatment with immune checkpoint inhibitors.
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Reducing long-term pain after lung resection using transthoracic, out-of-cage, or hybrid robotic approaches
We will test whether using subcostal/subxiphoid ('out of cage') or a hybrid robotic approach causes less chronic pain than standard transthoracic robotic surgery in adults having lung resection.
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Proactive risk-based coordination to shorten time from surgery to post-operative radiation for head and neck cancer
This pilot tests whether an automated care-coordination system (PRONTO-HN) can help adults with oral or laryngeal squamous cell carcinoma begin post-operative radiotherapy within 42 days after surgery.
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Comparing paravertebral block methods to improve chest numbness and pain control after VATS lung resection
We will try three different paravertebral block methods to see which gives the best chest numbness and pain control after VATS lung surgery for adults.
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Cannabis use patterns and social and health effects in young adults
We will follow 18–24-year-olds who use cannabis at least weekly for two years to see if different patterns of product type, frequency, and dosage are linked to social and health outcomes.
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Adding fostemsavir to reduce inflammation in people with well-controlled HIV
This trial will test whether adding fostemsavir to current HIV treatment lowers inflammation and heart disease risk for people with well-controlled HIV who have detectable sgp120.
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Trazodone for insomnia in adults 65 and older
This trial will test whether taking low-dose trazodone at bedtime helps reduce insomnia symptoms in adults aged 65 and older compared with a placebo.
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Postoperative radiotherapy after chemo-immunotherapy and surgery for stage III non-small cell lung cancer
This study tests whether adding postoperative radiotherapy to the involved lymph node regions helps people with stage III non-small cell lung cancer who still have cancer in their lymph nodes after neoadjuvant chemo-immunotherapy and surgery.
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Creating a video library of endoscopy procedures to improve AI quality reporting and education
This study is creating a video library of endoscopy procedures to help improve the quality of care for patients with rectal cancer or inflammatory bowel disease and to train future doctors.
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Comparing closure techniques after removing large colorectal polyps
This study tests if closing the site after removing large flat colorectal polyps can help prevent complications and reduce the chance of the polyps coming back.
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Long-term high-dose lisdexamfetamine treatment for methamphetamine use disorder
This trial will try giving adults with moderate to severe methamphetamine use disorder a 25-week course of high-dose lisdexamfetamine plus their usual care to see if it helps them stay in treatment and cut down on methamphetamine use compared with placebo.
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Comparing Optilume catheter and Rezum water-vapor therapy for enlarged prostate (BPH)
This compares Optilume catheter and Rezum water-vapor therapy to see which better eases lower urinary tract symptoms in men with enlarged prostates (BPH) sized 30–100 g.
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Neoadjuvant Cemiplimab + Dupilumab in Early-Stage NSCLC
This study tests whether giving cemiplimab with dupilumab before surgery can be safe and help shrink tumors in people with early-stage non-small cell lung cancer.
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Pulsed radiotherapy with immunotherapy for metastatic non-small cell lung cancer that stopped responding to prior treatment
This phase 1 study tests whether giving adaptive pulsed radiotherapy together with PD-(L)1 inhibitors is safe and can help people with metastatic NSCLC whose cancer has progressed on immunotherapy.
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Ketamine paired with Acceptance and Commitment Therapy for people with alcohol problems and depression
This will test whether combining ketamine infusions with Acceptance and Commitment Therapy helps adults who have both alcohol use disorder and treatment-resistant depression.
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Routine versus on-demand ECMO during lung transplant
This trial tests whether using ECMO routinely during lung transplant or only when needed leads to fewer complications for people having a lung transplant.
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Portable chest device to detect lung fluid in people with heart failure
This project tests a small chest bioimpedance device to see if it can detect early lung fluid buildup in adults with heart failure.
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Autonomous AI vs AI-assisted human optical diagnosis for colorectal polyps
A computer-aided AI system is tested to predict the nature of colorectal polyps during colonoscopy and compare its autonomous predictions with those of human doctors using AI assistance.
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Improving early detection of liver cancer using advanced ultrasound techniques
This study is testing new ultrasound techniques to see if they can help doctors find liver cancer earlier in adults who are already being checked for it.
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Open lung extubation strategy for patients after abdominal surgery
This study is testing if a new way to take patients off breathing machines after abdominal surgery can reduce lung problems compared to the usual method.
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Reducing recurrence of large colorectal polyps after removal
This study is testing if a new method called hybrid argon plasma coagulation can help prevent large colorectal polyps from coming back after they've been removed, compared to the usual treatment.
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Breast cancer: applying non-thermal plasma after tumor removal to see if it is safe and tolerable
This study tests whether applying non-thermal plasma to the tumor bed after lumpectomy is safe and tolerable in breast cancer patients and whether it affects cosmetic outcomes.
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Web-based nursing support to help older adults with coronary heart disease become more active
This study tests a new online nursing program to help older adults with coronary heart disease become more active and improve their quality of life.
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Using kinematic theory to help diagnose Parkinson's disease
This study is testing new ways to use movement analysis to help tell the difference between people with Parkinson's disease, related conditions, and healthy individuals.
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Improving bone health in adults with type 1 diabetes using automated insulin delivery
This study is testing if using an automated insulin delivery system can help improve bone health in adults with type 1 diabetes.
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Exploring how CBD affects THC's psychoactive effects
This study is testing how different amounts of CBD can change the effects of THC when people inhale them together.
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Impact of Probiotics on Patients with ALS and Frontotemporal Dementia
This study is testing if a probiotic supplement can help people with ALS and frontotemporal dementia feel better and improve their health compared to those who get a placebo.
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Using aerosol glycerine to find air leaks in the lungs during surgery
This study is testing a new way to find air leaks in the lungs during surgery using a special mist to help doctors improve recovery for patients having lung operations.
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Using cryogenic catheters for lung biopsy and treatment
This study is testing a new way to take lung biopsies and treat lung lesions using cold technology to see if it can be safer and more effective than traditional methods.
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High dose stimulant treatment for methamphetamine users
This study is testing whether a high dose of a medication called lisdexamfetamine, along with support and rewards, can help adults who use methamphetamine reduce their drug use more effectively than standard treatment alone.
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Detecting and treating air leaks from lungs during surgery
This study is testing a new way to find and fix air leaks during lung surgery using a special glue to help patients recover better and faster.
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Comparing different doses of triamcinolone for knee osteoarthritis pain relief
This study is testing different doses of a knee injection to see which one helps people with knee osteoarthritis pain the most while causing the least side effects.
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Dietary intervention for lung cancer patients receiving immune therapy
This study is testing if a special diet that increases fiber can help lung cancer patients feel better while they are receiving immune therapy.
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Using Mycophenolate Mofetil for Systemic Sclerosis with Mild Lung Issues
This study is testing if a medication called mycophenolate mofetil can help people with systemic sclerosis and mild lung problems feel better over 96 weeks.
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Virtual group speech therapy for head and neck cancer patients
This study tests a new online group speech therapy program for head and neck cancer patients to see if it helps them stick to their treatment and avoid swallowing problems during their care.
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New fiducial marker system for cancer treatment
This study is testing a new device that helps doctors place markers more accurately in cancer patients to improve treatment targeting.
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Using targeted radiotherapy to improve outcomes in men with metastatic prostate cancer
This study is testing if a special type of targeted radiotherapy can help men with advanced prostate cancer who have responded well to standard treatments stay healthy longer.
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Comparing two types of shoulder injections for osteoarthritis pain relief
This study is testing whether a new shoulder injection called Cingal can help people with moderate to severe shoulder osteoarthritis feel less pain compared to a standard cortisone injection.
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Combining vertebroplasty with radiation therapy for spine metastases pain relief
This study is testing whether combining a procedure to strengthen the spine with radiation therapy can help people with spine cancer feel less pain and lower their chances of fractures.
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AI-assisted detection of adenomas during colonoscopies
This study is testing whether a computer system can help doctors find more adenomas during colonoscopies for people aged 45-89 in Canada.
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Using infliximab eye drops to prevent glaucoma after corneal transplant surgery
This study is testing if infliximab eye drops can help prevent glaucoma in patients after they have corneal transplant surgery.
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Using cannabis to help treat symptoms of multiple sclerosis
This study is testing if cannabis products, like THC and CBD, can help people with multiple sclerosis manage their symptoms better.
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Exploring the use of F-choline PET imaging for various medical conditions
This study is testing if F-choline PET imaging can help diagnose certain cancers and other medical conditions better than current imaging methods.
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Stereotactic radiotherapy for patients with metastatic head and neck cancer showing limited progression
This study is testing if a special type of targeted radiation therapy can help people with metastatic head and neck cancer who are seeing limited disease progression while on other treatments.
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Understanding risks of same-day noncardiac surgery
This study looks at the risks and complications that may happen to adults having same-day noncardiac surgery to help doctors better understand how to keep patients safe and improve their quality of life.
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Celiac plexus neurolysis with and without bupivacaine for pancreatic cancer pain relief
This study is testing whether adding a local anesthetic called bupivacaine to a pain relief procedure for pancreatic cancer can improve pain control for patients.
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Adaptive radiotherapy for oropharynx cancer
This study is testing if adjusting radiation treatment using MRI during therapy can help people with advanced throat cancer swallow better after their treatment compared to standard care.
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Using heparin to improve success after finger replantation
This study is testing if giving heparin through an IV can help improve the chances of success for people who have had their fingers amputated and are getting them reattached.
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Using advanced ultrasound techniques to improve liver cancer diagnosis
This study is testing new ultrasound techniques to see if they can help doctors better diagnose liver cancer in patients with liver lesions.
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Investigating inflammatory markers in glaucoma after corneal transplantation
This study is trying to find out if certain markers in the tears and eye fluid of people who have had corneal transplants can help spot early signs of glaucoma.
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Treatment for acute stroke with carotid artery issues
This study is testing if combining a procedure to open blocked carotid arteries with a treatment to remove blood clots can help people who have had a stroke feel better after 90 days.
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Using laser treatment to manage glaucoma in patients receiving a Boston keratoprosthesis
This study is testing a laser treatment to see if it can help manage glaucoma in patients who have received an artificial cornea to improve their vision.
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Analyzing tear samples to identify eye surface conditions
This study is testing tear samples from patients with eye surface conditions like dry eye and allergies to see if they can identify unique markers for these issues.
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Short-course radiation therapy for oropharynx cancer
This study is testing a shorter and more targeted radiation treatment for people with HPV-related throat cancer to see if it can reduce side effects while still being effective.
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Managing unruptured intracranial aneurysms with different treatment options
This study is testing whether surgery or a less invasive treatment is better for people with unruptured brain aneurysms compared to just monitoring their condition.
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Registry for advanced endoscopic procedures
This study is collecting information from patients who are having advanced endoscopy procedures for gastrointestinal diseases to see how well these treatments work and improve patient care.
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Understanding side effects of combined cancer treatments
This study is trying to see how often severe side effects happen when people with cancer receive both molecular therapies and radiotherapy together compared to when they get them separately.
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Focal brachytherapy boost combined with stereotactic radiotherapy for prostate cancer
This study is testing a new combination treatment for prostate cancer to see if it causes less urinary problems and improves quality of life compared to standard care.
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Using PSMA-PET imaging to predict prostate cancer progression and treatment response
This study is testing a new imaging method called PSMA-PET to see if it can better detect advanced prostate cancer and help doctors make better treatment decisions for patients.
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Using ultrasound techniques to diagnose nonalcoholic steatohepatitis
This study is testing new ultrasound techniques to see if they can accurately diagnose nonalcoholic steatohepatitis in people with fatty liver disease without needing a liver biopsy.
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Improving Aortic Endovascular Repair with Personalized Biomechanical Modeling
This study is testing a new computer program that helps doctors perform safer and more effective surgeries for abdominal aortic aneurysms by using personalized imaging of each patient's blood vessels.
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New ultrasound tool to measure lung strain in ICU patients
This study is testing a new ultrasound tool to see if it can help doctors measure lung strain in ICU patients on ventilators to prevent lung injuries.
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Evaluating the impact of technology in radiotherapy for cancer patients
This study is trying to see how technology in radiotherapy affects cancer patients by collecting their health information and experiences during treatment.
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Assessing the safety of N-13 ammonia in heart imaging
This study is testing if using a new substance called N-13 ammonia in heart scans is safe for adults needing to check their heart function and blood flow.
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Improving corneal graft resistance in artificial corneas
This study is testing a new method using riboflavin and UV light to see if it can make artificial corneas last longer and prevent them from melting for people who can't have regular corneal transplants.
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Treatment options for brain arteriovenous malformations
This study is testing different treatment options for people with brain arteriovenous malformations to see which ones work best in preventing serious problems like stroke or death over ten years.
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Timing of glaucoma drainage device placement with Boston keratoprosthesis
This study is trying to find out the best time to place a glaucoma drainage device for patients getting a Boston keratoprosthesis to help prevent vision loss from glaucoma.
Quick answers
How many clinical trials run by Centre hospitalier de l'Université de Montréal (CHUM) are recruiting right now?
72, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 10 countries. The most sites are in Canada (72 trials), United States (2 trials), France (2 trials), Netherlands (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 12, Phase 4: 3, Phase 1/2: 3, Phase 3: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.