Using aerosol glycerine to find air leaks in the lungs during surgery
Official title: Validation of a System Using Aerosol Glycerine to Detect and Localize Intraoperatively Pulmonary Air Leaks
Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT05971719 · Data updated 2026-11-12
This study is testing a new way to find air leaks in the lungs during surgery using a special mist to help doctors improve recovery for patients having lung operations.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montreal) |
| Status | Recruiting |
| Started | July 20, 2023 |
| Main results expected | July 1, 2027 |
| Study ends | July 1, 2027 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT05971719 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients undergoing lung transplant surgery or those who are organ donors ineligible to donate lungs.
✕Probably not a fit
Healthy individuals will not benefit from this study as they do not meet the eligibility criteria.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to validate a novel system that uses aerosol glycerine to detect and localize pulmonary air leaks during thoracic surgery. Air leaks are a common complication that can lead to increased postoperative morbidity and costs, particularly following lobectomy. The traditional method for detecting these leaks, the submersion test, is not suitable for video-assisted thoracic surgery. By creating visible glycerine aerosol smoke that flows through any leaks, this approach seeks to improve surgical outcomes and reduce recovery times for patients undergoing lung procedures.
Why it matters
Potential benefit: If successful, this method could significantly reduce postoperative complications and hospital stays for patients undergoing lung surgery.
How similar studies have gone: While this approach is innovative, it is not clear if similar studies have been conducted, making this a potentially novel intervention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing lung transplant surgery * Organ donor ineligible to donate lungs Exclusion Criteria: * Healthy individuals
Where it's running
-
Chum
Montreal, Canada Recruiting
Study contacts
- Study coordinator: Moishe Liberman, MD
- Email: moishe.liberman@umontreal.ca
- Phone: 514-890-8000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using intraoperative ventilation to predict postoperative air leaks after thoracoscopic lobectomy or segmentectomy
This project will try using intraoperative ventilation during thoracoscopic lobectomy or segmentectomy to see if it can predict which patients will have postoperative air leaks.
-
Gas analyzer for chest drains to detect pleural air leaks
This study will test a small reusable gas analyzer that connects to chest drains to detect air leaks in adults undergoing thoracic surgery.
-
Detecting and treating air leaks from lungs during surgery
This study is testing a new way to find and fix air leaks during lung surgery using a special glue to help patients recover better and faster.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.