Using cryogenic catheters for lung biopsy and treatment
Official title: Defining a Technique for the Use of Cryogenic Catheters for Biopsy and Ablation for the Diagnostic and Treatment of Pulmonary Lesions: An Ex-Vivo Human Lung Model Study.
Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT05948904 · Data updated 2026-11-12
This study is testing a new way to take lung biopsies and treat lung lesions using cold technology to see if it can be safer and more effective than traditional methods.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Status | Recruiting |
| Started | November 3, 2023 |
| Main results expected | April 1, 2027 |
| Study ends | April 1, 2027 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT05948904 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients undergoing lung transplant surgery.
✕Probably not a fit
Patients who are organ donors ineligible to donate lungs or healthy individuals may not receive any benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop a standardized technique for using cryogenic catheters in transbronchial cryobiopsy and cryoablation of pulmonary lesions. By utilizing an ex-vivo human lung model, the researchers will explore the effectiveness of cryotechnology as a minimally invasive alternative to traditional surgical lung biopsy and resection. The goal is to improve the quality of tissue samples and reduce complications associated with current methods. This approach could enhance patient safety and outcomes in lung disease management.
Why it matters
Potential benefit: If successful, this technique could provide a safer and more effective method for diagnosing and treating lung lesions.
How similar studies have gone: While promising results have been achieved using cryotechnology, this specific approach to transbronchial interventions is novel and has not been extensively tested in humans.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing lung transplant surgery Exclusion Criteria: * Organ donor ineligible to donate lungs * Healthy individuals
Where it's running
-
Chum
Montreal, Quebec, Canada Recruiting
Study contacts
- Study coordinator: Moishe Liberman, MD
- Email: moishe.liberman@umontreal.ca
- Phone: 514-890-8000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.