Using cryogenic catheters for lung biopsy and treatment

Defining a Technique for the Use of Cryogenic Catheters for Biopsy and Ablation for the Diagnostic and Treatment of Pulmonary Lesions: An Ex-Vivo Human Lung Model Study.

Not applicable Interventional Centre hospitalier de l'Université de Montréal (CHUM) · NCT05948904

This study is testing a new way to take lung biopsies and treat lung lesions using cold technology to see if it can be safer and more effective than traditional methods.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorCentre hospitalier de l'Université de Montréal (CHUM) Academic / other
Locations1 site (Montreal, Quebec)
Trial IDNCT05948904 on ClinicalTrials.gov

What this trial studies

This study aims to develop a standardized technique for using cryogenic catheters in transbronchial cryobiopsy and cryoablation of pulmonary lesions. By utilizing an ex-vivo human lung model, the researchers will explore the effectiveness of cryotechnology as a minimally invasive alternative to traditional surgical lung biopsy and resection. The goal is to improve the quality of tissue samples and reduce complications associated with current methods. This approach could enhance patient safety and outcomes in lung disease management.

Who should consider this trial

Good fit: Ideal candidates for this study are patients undergoing lung transplant surgery.

Not a fit: Patients who are organ donors ineligible to donate lungs or healthy individuals may not receive any benefit from this study.

Why it matters

Potential benefit: If successful, this technique could provide a safer and more effective method for diagnosing and treating lung lesions.

How similar studies have performed: While promising results have been achieved using cryotechnology, this specific approach to transbronchial interventions is novel and has not been extensively tested in humans.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing lung transplant surgery

Exclusion Criteria:

* Organ donor ineligible to donate lungs
* Healthy individuals

Where this trial is running

Montreal, Quebec

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lung DiseasesLungcryobiopsycryoablationtransbronchial intervention
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.