Clinical trial Recruiting at 1 site Observational Ages 18 and up

Improving early detection of liver cancer using advanced ultrasound techniques

Official title: Quantitative Ultrasound to Improve Detection and Diagnosis of Liver Cancer

Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT06345508 · Data updated 2026-11-12

This study is testing new ultrasound techniques to see if they can help doctors find liver cancer earlier in adults who are already being checked for it.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment328 (estimated)
SponsorCentre hospitalier de l'Université de Montréal (CHUM)
Academic / other
Locations1 site (Montreal, Quebec)
StatusRecruiting
StartedAugust 20, 2024
Main results expectedJune 2029
Study endsDecember 2029
Registry record updatedMarch 20, 2026
Trial IDNCT06345508 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients scheduled for ultrasound or MRI surveillance of hepatocellular carcinoma or those undergoing MRI for liver nodule characterization.

Probably not a fit

Patients who have previously received locoregional or systemic therapy for liver cancer may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the early detection of hepatocellular carcinoma (HCC) by utilizing innovative quantitative ultrasound (QUS) techniques. The research will compare the effectiveness of conventional B-mode ultrasound with advanced QUS methods, including shear wave viscoelastography and sub-resolution cellular imaging, in identifying liver nodules. The study will involve adult patients undergoing routine ultrasound or MRI surveillance for liver cancer, with MRI serving as the reference standard for diagnosis. By improving detection rates, the study seeks to facilitate earlier treatment and improve survival outcomes for patients with liver cancer.

Why it matters

Potential benefit: If successful, this study could significantly improve the early detection of liver cancer, leading to better treatment options and improved survival rates for patients.

How similar studies have gone: Other studies have shown promise in using advanced imaging techniques for cancer detection, suggesting that this approach may yield beneficial results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Adult patients scheduled for US- or MRI-based surveillance of HCC or undergoing MRI-based imaging for characterization of liver nodules as part of their clinical standard of care.

Exclusion Criteria:

\- Patients with prior locoregional or systemic therapy.

Where it's running

  • Centre Hospitalier de l'Université de Montréal (CHUM)
    Montreal, Quebec, Canada
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.