Understanding risks of same-day noncardiac surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The VALIANCE Study is a large-scale observational cohort involving 15,000 adults undergoing elective same-day noncardiac surgery, followed for 90 days post-surgery. The study aims to identify the incidence of major cardiovascular complications and other adverse events, while also assessing changes in quality of life. It will develop risk prediction tools based on various validated assessments, including the Duke Activity Status Index and Clinical Frailty Scale, to better inform patient selection and risk stratification. This research addresses a growing trend in outpatient surgery, particularly among higher-risk patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 45-64 years of age with at least one risk factor, or ≥65 years of age;
* undergoing elective noncardiac same-day surgery;
* planned duration in the operating room 60 minutes or more;
* provided written consent.

Exclusion Criteria:

* intervention does not require the presence of an anesthesiologist;
* procedure is performed by a nonsurgical specialty (e.g., gastroenterology, pneumology, radio-oncology or radiology);
* intervention is an ophthalmologic procedure;
* previously enrolled in the VALIANCE study.

Where it's running

• Wake Forest Baptist Medical Centre
  Winston-Salem, North Carolina, United States Recruiting
• Cleveland Clinic Foundation Fairview Campus
  Cleveland, Ohio, United States Recruiting
• MD Anderson Cancer Center
  Houston, Texas, United States Recruiting
• Memorial Hermann Texas Medical Center UT Health
  Houston, Texas, United States Recruiting
• Hamilton General Hospital
  Hamilton, Ontario, Canada Recruiting
• Juravinski Hospital and Cancer Centre
  Hamilton, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Emmanuelle Duceppe, MD, PhD — Centre hospitalier de l'Université de Montréal (CHUM)
• Study coordinator: Melodie Fanay Boko, MSc
• Email: valiance.chum@ssss.gouv.qc.ca
• Phone: 514-890-8000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.