Using heparin to improve success after finger replantation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of intravenous unfractionated heparin in enhancing the success rates of digital replantation and revascularization in patients who have experienced traumatic finger amputations. Participants will receive a continuous intravenous drip of heparin to assess its impact on the viability of the replanted digit compared to those who do not receive the treatment. The study will also evaluate potential postoperative complications associated with heparin use, such as bleeding and thrombocytopenia, while considering various patient factors like smoking status and comorbidities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All replantation and revascularization patients who are accepted into the CEVARMU program at the Centre hospitalier de l'Université de Montréal

Exclusion Criteria:

* Patients on anticoagulants, other than ASA, prior to admission (i.e. Coumadin, Eliquis, Pradaxa, Plavix, or similar medications)
* Patients with a contraindication for heparin (e.g. coagulopathy, acute ulcers, thrombocytopenia, severe liver damage, shock)
* Patients who suffered an amputation in the level of the carpal tunnel and proximal to it
* Patients who experienced a degloving injury

Where it's running

• Chum
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Bruno Mastropasqua, MD FRCSC — Université de Montréal
• Study coordinator: Linda M Zhu
• Email: linda.zhu@mail.mcgill.ca
• Phone: 5148908000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.