Portable chest device to detect lung fluid in people with heart failure
Official title: A Portable Thoracic Impedance Device for Detecting Pulmonary Congestion in Heart Failure Patients
Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT06604468 · Data updated 2026-11-12
This project tests a small chest bioimpedance device to see if it can detect early lung fluid buildup in adults with heart failure.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Status | Recruiting |
| Started | September 1, 2025 |
| Main results expected | June 30, 2026 |
| Study ends | September 1, 2026 |
| Registry record updated | October 6, 2025 |
| Trial ID | NCT06604468 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with a diagnosis of heart failure and a hospitalization or emergency visit for decompensated heart failure within the past 12 months who can give informed consent are ideal candidates.
✕Probably not a fit
Patients who are pregnant, have implanted thoracic electronic devices (e.g., pacemaker or defibrillator), are in intensive/coronary care, or cannot provide consent are excluded and may not benefit from this device.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, cross-sectional observational study compares a portable thoracic bioimpedance tomography (TBIT) device with portable lung ultrasound, CT imaging, blood biomarkers, and symptom questionnaires to measure pulmonary congestion. Adults are recruited during hospital admissions or outpatient visits at heart failure and nephrology clinics at CHUM and undergo on-site TBIT measurements, lung ultrasound B-line scoring, CT-derived thoracic water content when available, and NT-proBNP testing. Correlations will be analyzed using methods such as Spearman correlation and mixed-effects models, and study procedures are observational so patient treatment is not changed based on TBIT results. The aim is to validate TBIT as a non-invasive, cost-effective tool for earlier detection of lung congestion that could support outpatient management.
Why it matters
Potential benefit: If successful, the device could allow earlier detection of pulmonary congestion outside the hospital and help guide outpatient fluid management to reduce heart failure hospitalizations.
How similar studies have gone: Prior research using thoracic bioimpedance and lung ultrasound has shown promising correlations with pulmonary congestion, but portable TBIT devices are relatively novel and require further validation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older. * Diagnosed with heart failure, defined by the following criterion: hospitalization or an emergency visit for decompensated heart failure (pulmonary edema) within the last 12 months. Exclusion Criteria: * Pregnant women at the time of eligibility evaluation. * Presence of an implanted electronic device in the thorax, such as a pacemaker or defibrillator. * Inability to provide informed consent. * Admission to intensive care or the coronary care unit.
Where it's running
-
Chum
Montreal, Quebec, Canada Recruiting
Study contacts
- Study coordinator: William Beaubien-Souligny, MD PhD
- Email: william.beaubien-souligny.med@ssss.gouv.qc.ca
- Phone: 15148908000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using Apple Watch data to predict heart failure outcomes
This study is testing if data from Apple Watches can help predict heart failure problems and the chances of needing to go back to the hospital for patients with heart failure.
-
Comparing Aortix Device to Diuretics for Acute Heart Failure
This study is testing whether the Aortix device can help people with acute heart failure who aren't responding to diuretics feel better compared to standard treatment.
-
Myocardial Energetics Across Cardiovascular Disease Spectrum Using 31P-MRS
Researchers are testing whether phosphorus-31 magnetic resonance spectroscopy (31P-MRS) can map heart energy metabolism across healthy people and patients with various heart conditions.
-
Tailored digital support to cut sedentary time in long-term cardiac rehab
In adults in a long-term cardiac rehabilitation program, this study tests whether a personalized behavioural program with digital tools can reduce daily sitting time.
-
NT-proBNP–guided heart failure screening for people 65+ in rural China
This study tests whether using NT-proBNP blood tests to guide heart failure screening in adults 65 and older in rural China can find unrecognized heart problems more effectively than symptom-based screening.
-
Voice-based detection of heart failure deterioration using Noah Labs Vox
This study tests whether a voice-analysis app can flag worsening heart failure in adults by comparing its alerts to standard weight-based monitoring.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.