Clinical trial Recruiting at 1 site Observational Ages 18 and up

New ultrasound tool to measure lung strain in ICU patients

Official title: A Pilot Study of a New Ultrasonographic Tool to Assess Regional Pulmonary Strain in Mechanically Ventilated Patients Suffering From Pulmonary Diseases in an Intensive Care Setting.

Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT03405779 · Data updated 2026-11-12

This study is testing a new ultrasound tool to see if it can help doctors measure lung strain in ICU patients on ventilators to prevent lung injuries.

More Mechanical Ventilation Complication trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10 (estimated)
SponsorCentre hospitalier de l'Université de Montréal (CHUM)
Academic / other
Locations1 site (Montreal, Quebec)
StatusRecruiting
StartedMarch 12, 2018
Main results expectedJanuary 1, 2026
Study endsFebruary 1, 2026
Registry record updatedSeptember 18, 2025
Trial IDNCT03405779 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult ICU patients under mechanical ventilation with pulmonary diseases and a static lung compliance of less than 40 mL/cm H2O.

Probably not a fit

Patients with obesity, previous thoracic procedures, or those who have participated in the study before may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a dataset of regional pulmonary strain values in patients with pulmonary diseases who are on mechanical ventilation in an intensive care unit. The study will utilize ultrasonographic imaging to assess local pleural strain in four specific areas of the lungs, helping to identify excessive pulmonary strain that could lead to ventilator-induced lung injury. By analyzing lung ultrasonographic sequences, the researchers hope to develop a tool for early detection of pulmonary overdistension, which could improve mechanical ventilation management. The findings from this pilot study will inform larger-scale studies in the future.

Why it matters

Potential benefit: If successful, this study could lead to improved management of mechanical ventilation, reducing the risk of lung injury in critically ill patients.

How similar studies have gone: While the use of ultrasonography for cardiac strain measurements is established, this specific application for pulmonary strain assessment is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult intensive care patients under mechanical ventilation suffering from a pulmonary disease with a static lung compliance of less than 40 mL/cm H2O.

Exclusion Criteria:

* Obesity (Body Mass Index superior to 30 kg/m2)
* Previous thoracic procedure (chest tube, thoracotomy, thoracoscopy)
* Intra-abdominal pressure inferior to 15 mm Hg (if available)
* Previous participation to the study

Where it's running

  • Centre Hospitalier de l'Université de Montréal (CHUM)
    Montreal, Quebec, Canada
    Recruiting

Study contacts

  • Principal investigator: Martin Girard, MD,FRCPC — Centre hospitalier de l'Université de Montréal (CHUM)
  • Study coordinator: Martin Girard, MD,FRCPC
  • Email: martin.girard@umontreal.ca
  • Phone: 514-890-8000

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.