New ultrasound tool to measure lung strain in ICU patients
A Pilot Study of a New Ultrasonographic Tool to Assess Regional Pulmonary Strain in Mechanically Ventilated Patients Suffering From Pulmonary Diseases in an Intensive Care Setting.
Centre hospitalier de l'Université de Montréal (CHUM) · NCT03405779
This study is testing a new ultrasound tool to see if it can help doctors measure lung strain in ICU patients on ventilators to prevent lung injuries.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) (other) |
| Locations | 1 site (Montreal, Quebec) |
| Trial ID | NCT03405779 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a dataset of regional pulmonary strain values in patients with pulmonary diseases who are on mechanical ventilation in an intensive care unit. The study will utilize ultrasonographic imaging to assess local pleural strain in four specific areas of the lungs, helping to identify excessive pulmonary strain that could lead to ventilator-induced lung injury. By analyzing lung ultrasonographic sequences, the researchers hope to develop a tool for early detection of pulmonary overdistension, which could improve mechanical ventilation management. The findings from this pilot study will inform larger-scale studies in the future.
Who should consider this trial
Good fit: Ideal candidates are adult ICU patients under mechanical ventilation with pulmonary diseases and a static lung compliance of less than 40 mL/cm H2O.
Not a fit: Patients with obesity, previous thoracic procedures, or those who have participated in the study before may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of mechanical ventilation, reducing the risk of lung injury in critically ill patients.
How similar studies have performed: While the use of ultrasonography for cardiac strain measurements is established, this specific application for pulmonary strain assessment is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult intensive care patients under mechanical ventilation suffering from a pulmonary disease with a static lung compliance of less than 40 mL/cm H2O. Exclusion Criteria: * Obesity (Body Mass Index superior to 30 kg/m2) * Previous thoracic procedure (chest tube, thoracotomy, thoracoscopy) * Intra-abdominal pressure inferior to 15 mm Hg (if available) * Previous participation to the study
Where this trial is running
Montreal, Quebec
- Centre Hospitalier de l'Université de Montréal (CHUM) — Montreal, Quebec, Canada (RECRUITING)
Study contacts
- Principal investigator: Martin Girard, MD,FRCPC — Centre hospitalier de l'Université de Montréal (CHUM)
- Study coordinator: Martin Girard, MD,FRCPC
- Email: martin.girard@umontreal.ca
- Phone: 514-890-8000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Mechanical Ventilation Complication, Ventilator-Induced Lung Injury