New ultrasound tool to measure lung strain in ICU patients
Official title: A Pilot Study of a New Ultrasonographic Tool to Assess Regional Pulmonary Strain in Mechanically Ventilated Patients Suffering From Pulmonary Diseases in an Intensive Care Setting.
Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT03405779 · Data updated 2026-11-12
This study is testing a new ultrasound tool to see if it can help doctors measure lung strain in ICU patients on ventilators to prevent lung injuries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Status | Recruiting |
| Started | March 12, 2018 |
| Main results expected | January 1, 2026 |
| Study ends | February 1, 2026 |
| Registry record updated | September 18, 2025 |
| Trial ID | NCT03405779 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult ICU patients under mechanical ventilation with pulmonary diseases and a static lung compliance of less than 40 mL/cm H2O.
✕Probably not a fit
Patients with obesity, previous thoracic procedures, or those who have participated in the study before may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a dataset of regional pulmonary strain values in patients with pulmonary diseases who are on mechanical ventilation in an intensive care unit. The study will utilize ultrasonographic imaging to assess local pleural strain in four specific areas of the lungs, helping to identify excessive pulmonary strain that could lead to ventilator-induced lung injury. By analyzing lung ultrasonographic sequences, the researchers hope to develop a tool for early detection of pulmonary overdistension, which could improve mechanical ventilation management. The findings from this pilot study will inform larger-scale studies in the future.
Why it matters
Potential benefit: If successful, this study could lead to improved management of mechanical ventilation, reducing the risk of lung injury in critically ill patients.
How similar studies have gone: While the use of ultrasonography for cardiac strain measurements is established, this specific application for pulmonary strain assessment is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult intensive care patients under mechanical ventilation suffering from a pulmonary disease with a static lung compliance of less than 40 mL/cm H2O. Exclusion Criteria: * Obesity (Body Mass Index superior to 30 kg/m2) * Previous thoracic procedure (chest tube, thoracotomy, thoracoscopy) * Intra-abdominal pressure inferior to 15 mm Hg (if available) * Previous participation to the study
Where it's running
-
Centre Hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec, Canada Recruiting
Study contacts
- Principal investigator: Martin Girard, MD,FRCPC — Centre hospitalier de l'Université de Montréal (CHUM)
- Study coordinator: Martin Girard, MD,FRCPC
- Email: martin.girard@umontreal.ca
- Phone: 514-890-8000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.