Open lung extubation strategy for patients after abdominal surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the feasibility of a multicenter randomized controlled trial comparing two extubation strategies: 'open lung' and 'conventional' in patients undergoing elective intra-abdominal surgery under general anesthesia. It will involve 216 adult patients at moderate or high risk of postoperative pulmonary complications, who will be randomly assigned to one of the two strategies. The study will measure adherence to the extubation protocol and the rates of postoperative pulmonary complications in both groups. The findings will help inform future definitive trials on the effectiveness of these strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients (18 years of age or over)
* Elective intra-abdominal surgery under general anesthesia.
* Moderate or high risk of postoperative pulmonary complication according to the ARISCAT score (score of 26 or more)
* Planned postoperative hospitalization

Exclusion Criteria:

* Expected or known difficult intubation according to the treating anesthesiologist
* Postoperative mechanical ventilation (planned or unplanned)
* General anesthesia performed outside the main operating room

Where it's running

• Unity Health Network
  Toronto, Ontario, Canada Recruiting
• Centre Hospitalier de l'Université de Montréal (CHUM)
  Montreal, Quebec, Canada Recruiting
• CHU de Québec - Université Laval
  Québec, Quebec, Canada Recruiting
• Royal Columbian Hospital
  Vancouver, British Columbia, Canada Not yet recruiting
• The Ottawa Hospital
  Ottawa, Ontario, Canada Not yet recruiting

Study contacts

• Principal investigator: Martin Girard, MD — Centre hospitalier de l'Université de Montréal (CHUM)
• Study coordinator: Martin Girard, MD
• Email: martin.girard@umontreal.ca
• Phone: 514-890-8000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.