Timing of glaucoma drainage device placement with Boston keratoprosthesis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the optimal timing for the implantation of a glaucoma drainage device (GDD) in patients receiving a Boston keratoprosthesis (KPro) for corneal transplantation. The KPro is used to replace a damaged cornea in patients with a history of failed corneal transplants, but it can lead to complications such as glaucoma. The study aims to determine the best approach to prevent glaucoma-related vision loss by assessing the timing of GDD placement in relation to KPro surgery. By analyzing patient outcomes, the study seeks to establish guidelines for managing glaucoma in this complex patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Candidate for corneal transplantation due to loss of corneal clarity
* Verifiable history of one or more previous full thickness donor corneal transplantation failure
* Pre-operative visual acuity of ≤20/80 or worse in the surgical eye
* Age ≥18 years
* Physical condition suitable for undergoing surgery

Exclusion Criteria:

* Terminal glaucoma
* Terminal retinal diseases

Where it's running

• Centre Hospitalier de l'Université de Montréal (CHUM)
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Mona Harissi-Dagher, MD, FRCSC — Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal
• Study coordinator: Mona Harissi-Dagher, MD, FRCSC
• Email: monadagher@hotmail.com
• Phone: 1-514-890-8000

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.