Detecting and treating air leaks from lungs during surgery
Defining Novel Strategies for the Diagnosis and Treatment of Intraoperative Air Leaks: An Ex-Vivo Human Lung Model Study
This study is testing a new way to find and fix air leaks during lung surgery using a special glue to help patients recover better and faster.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Trial ID | NCT05854654 on ClinicalTrials.gov |
What this trial studies
This study focuses on developing a method to detect, quantify, and treat air leaks that occur during lung surgery using a bio-adhesive. It aims to establish a standardized ex-vivo human lung model to optimize the detection and treatment process. The study will involve multiple procedures on lung models obtained from organ donors who are ineligible for lung donation. By analyzing tissue samples and images, the researchers hope to identify the most effective configurations for managing air leaks, ultimately reducing postoperative complications and hospital stays.
Who should consider this trial
Good fit: Ideal candidates for this study are patients undergoing lung transplant surgery and organ donors who are ineligible to donate lungs.
Not a fit: Healthy individuals will not benefit from this study as they do not meet the eligibility criteria.
Why it matters
Potential benefit: If successful, this approach could significantly reduce complications and recovery time for patients undergoing lung surgery.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in managing surgical complications, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing lung transplant surgery * Organ donor ineligible to donate lungs Exclusion Criteria: * Healthy individuals
Where this trial is running
Montreal, Quebec
- Chum — Montreal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: Moishe Liberman, MD — Chum
- Study coordinator: Moishe Liberman, MD
- Email: moishe.liberman@umontreal.ca
- Phone: 514-890-8000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.