Improving Aortic Endovascular Repair with Personalized Biomechanical Modeling

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project integrates a biomechanical computer program with guidance code to simulate the endovascular repair (EVAR) procedure for abdominal aortic aneurysms (AAA). By utilizing preoperative CT scans and real-time fluoroscopy, the study aims to create a deformable vascular geometry tool that adapts to the patient's anatomy during surgery. This innovative approach seeks to reduce the need for toxic contrast agents, minimize intervention time, and enhance surgical outcomes through improved visualization of vascular structures. The methodology involves mathematical functions to compute vessel shapes influenced by endovascular tools, based on extensive biomechanical simulations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a clinical indication for EVAR/FEVAR of AAA and meeting anatomic inclusion criteria on preoperative enhanced CT-scan compatible with an endovascular repair.
* Willing and capable of providing informed consent

Exclusion Criteria:

* Contraindication to endovascular repair
* Creatinine clearance \< 30ml/min
* History of severe allergy to iodinated contrast (anaphylaxis, bronchospasm)
* Absence of recent previous thin-slice enhanced CT-scanner examination (stent planning based on MRI examination or non-enhanced CT examination).

Where it's running

• Centre Hospitalier de l'université de Montréal
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Gilles Soulez, MD,MSc — Centre hospitalier de l'Université de Montréal (CHUM)
• Study coordinator: Jennifer Satterthwaite, MSc
• Email: jennifer.satterthwaite.chum@ssss.gouv.qc.ca
• Phone: 514-890-8000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.