Sponsor or institution

Clinical trials and research at Cedars-Sinai Medical Center

• 78Clinical trials
• 410NIH research projects
• 3Countries

Newest trials

All recruiting trials (78)

• Fisetin for Lung Health in Older Adults

  Researchers are testing whether a short course of the supplement fisetin can improve lung function and aging-related biomarkers in people 60 and older, including both smokers and never-smokers.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT07676435

• Transcatheter vs. Surgical Repair for Degenerative Mitral Valve Disease

  This study compares TEER, a catheter-based repair, with traditional surgical mitral repair in people aged 60 and older with degenerative mitral valve disease to see which approach works better in the long run.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07605715

• Combining IV immunotherapy with liver-directed procedures to downstage hepatocellular carcinoma

  This tests whether giving IV immunotherapy (tremelimumab plus durvalumab) together with a liver-directed procedure (Y90, TACE, or RFA) can shrink or control hepatocellular carcinoma in adults with intermediate or advanced disease so more people may become eligible for liver transplant.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT07489976

• TAVR vs SAVR for severe bicuspid aortic valve stenosis

  This trial tests whether TAVR or SAVR works better for people with severe bicuspid aortic valve stenosis.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07413965

• Bupivacaine with Epinephrine Sprayed Under the Diaphragm During Laparoscopy

  This study tests whether spraying bupivacaine with epinephrine under the diaphragm during laparoscopic gynecologic surgery reduces postoperative shoulder pain.

  Recruiting Phase 4 Cedars-Sinai Medical Center · Los Angeles, California · NCT07400146

• Virtual reality to prevent delirium in the ICU

  This project will try daily 15-minute virtual reality sessions to see if they reduce delirium in high-risk, non-intubated adult surgical ICU patients.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07357389

• Lavender aromatherapy for anxiety and pain during awake ear, nose, and throat procedures

  This tests whether lavender aromatherapy used during awake ear, nose, and throat clinic procedures can reduce anxiety and pain in adults.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07299474

• Forehead photobiomodulation for people with mild Alzheimer's-related memory problems

  This study will see if a forehead light treatment (photobiomodulation) can improve thinking and change blood markers in people aged 55–89 with mild cognitive impairment or mild dementia from Alzheimer's disease.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07224607

• Heart-Healthy Cardio-Oncology Check for Prostate Cancer on ARPI Therapy

  This trial tests whether a cardio-oncology referral and shared care between your cardiologist and your primary clinician can help reduce heart-attack and stroke risk in men with advanced prostate cancer who are taking ARPI therapy.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT07223385

• Proactive Costs of Care support for people with gynecologic cancer

  This one-time, 30-minute educational session tries to help adults with gynecologic cancer (or their caregivers) who are starting a new systemic therapy learn to track medical costs, understand insurance and resources, and reduce financial stress.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07217262

• Food Is Medicine post-operative meal delivery for orthopaedic trauma patients

  This project will try whether delivering medically tailored meals and shakes for 12 days after surgery helps orthopaedic trauma patients recover better and improve metabolic lab markers.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07169448

• Intraoperative imaging of gastrointestinal cancers using pafolacianine (CYTALUX™)

  This trial will test whether an injection of CYTALUX™ (pafolacianine) with near-infrared imaging helps surgeons find gastric, esophageal, or appendiceal adenocarcinomas during surgery in adults.

  Recruiting Phase 4 Cedars-Sinai Medical Center · Los Angeles, California · NCT07124351

• AI-generated interactive video instructions for mitral valve repair

  This trial tests whether an AI-generated, interactive peri-operative video program can reduce unplanned hospital visits and readmissions for adults having elective, isolated mitral valve repair.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07036926

• High-intensity electromagnetic stimulation for bowel control after J-pouch surgery

  Aims to see if the Emsella chair can help people with a J pouch who have fecal incontinence after ulcerative colitis surgery.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT07034443

• Ivonescimab with carboplatin and docetaxel for early triple-negative breast cancer

  This trial will test whether adding ivonescimab to neoadjuvant carboplatin and docetaxel helps people with early-stage triple-negative breast cancer.

  Recruiting at 3 sites Phase 2 Cedars-Sinai Medical Center · Los Angeles, California and 3 other locations · NCT07017673

• Analyzing bacterial overgrowth in pancreatic cancer patients

  This study is testing how common bacterial overgrowth is in pancreatic cancer patients who are losing weight and seeing if it relates to their surgery status.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06988150

• Using a continuous glucose monitor (CGM) with education to improve satisfaction and quality of life for adults with diabetes

  This program will try whether providing inpatient diabetes education together with a continuous glucose monitor (CGM) improves satisfaction and quality of life for adults with Type 1 or Type 2 diabetes who use insulin.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06965803

• Enhanced recovery protocol for patients with complicated appendicitis

  This study is testing a new recovery plan for adults with complicated appendicitis to see if it helps them heal better and go home sooner after surgery.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06948071

• Hands-on nutrition demonstrations added to the Diabetes Prevention Program for people with prediabetes

  This project will test whether adding a 7-week series of healthy cooking and nutrition demos to the Diabetes Prevention Program helps adults at risk for prediabetes stay engaged and put healthy eating into daily life.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06897982

• Epigenetic therapy given before prostatectomy for men with prostate cancer

  This will try short courses of epigenetic drugs before prostatectomy to see if they make tumors more sensitive to the immune system in men with high-risk localized prostate cancer.

  Recruiting Early Phase 1 Cedars-Sinai Medical Center · Los Angeles, California · NCT06888102

• Staged kidney implantation with hypothermic oxygenated machine perfusion during combined heart and kidney transplants

  This trial will test whether keeping the donor kidney on oxygenated machine perfusion and implanting it later helps adults who are receiving both a heart and a kidney transplant.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06877169

• NLP-Based feedback to improve shared decision making for men with localized prostate cancer

  This trial will test an NLP+AI risk-communication feedback tool for doctors and men with newly diagnosed localized prostate cancer to see if it improves how treatment risks and tradeoffs are discussed and supports better decisions.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06856694

• Comparing Transcatheter and Surgical Aortic Valve Replacement for Bicuspid Aortic Valve Patients

  This study is testing whether a new heart valve replacement method works better than the traditional surgery for people with severe aortic stenosis and a bicuspid aortic valve.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06817148

• Support program for single mothers using assisted reproductive technology

  This study is trying to see if a support program can help single mothers who used assisted reproductive technology build better relationships with their support person during pregnancy.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06770972

• Rifaximin plus N-acetylcysteine (NAC) for diarrhea-predominant IBS

  This study will see if adding the supplement N-acetylcysteine (NAC) to rifaximin helps adults with IBS-D have less belly pain and firmer stools.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT06727422

• Improving maxillary sinus surgery accuracy with navigation technology

  This study tests if using navigation technology during sinus surgery helps adults with chronic sinus issues feel better compared to traditional surgery methods.

  Recruiting Phase 2/3 Cedars-Sinai Medical Center · Los Angeles, California · NCT06567821

• Zinc plus nicotinamide riboside for idiopathic pulmonary fibrosis

  This study will test whether taking zinc and nicotinamide riboside twice daily helps people over 50 with idiopathic pulmonary fibrosis and whether participants can complete the study remotely while receiving local care.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT06567717

• Choosing AVOID or RESIST to help weight management

  Participants will test whether choosing a self-regulatory strategy (AVOID or RESIST) leads to better adherence to a weight-management program for overweight and obese adults.

  Recruiting Cedars-Sinai Medical Center · Beverly Hills, California · NCT06521021

• Using circulating tumor DNA to tailor post-surgery treatment for HPV-related throat cancer

  This study is testing if adjusting cancer treatment based on blood tests for HPV DNA can help people with throat cancer after surgery feel better and improve their outcomes.

  Recruiting at 4 sites Phase 2 Cedars-Sinai Medical Center · Beverly Hills, California and 3 other locations · NCT06445114

• Cholesterol-lowering therapy for prostate cancer patients

  This study is testing whether lowering cholesterol with medication can help boost the immune system in men with prostate cancer who are being closely monitored.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT06437574

• Bladder preservation approach for patients with muscle-invasive bladder cancer and variant histology

  This study is testing a new treatment plan for patients with a specific type of bladder cancer to see if combining chemotherapy and radiation can help them better than past treatments.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT06417190

• Assessing esophageal temperature during atrial fibrillation ablation

  This study is testing if a new high-power ablation method can keep the esophagus cooler and reduce injury risk during heart procedures for people with atrial fibrillation.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06392932

• Real-time imaging of atherosclerosis activity after radiation therapy for cancer

  This study is testing whether special imaging can help doctors see how radiation therapy for cancer affects heart health in patients at risk for heart problems.

  Recruiting Early Phase 1 Cedars-Sinai Medical Center · Los Angeles, California · NCT06373497

• Comparing standard and lower pressure in laparoscopic surgery

  This study is testing if using lower pressure during laparoscopic gynecologic surgery can help reduce post-operative pain while still allowing doctors to see clearly during the procedure.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06338865

• Tart cherry and fish oil for aromatase inhibitor–related joint pain

  This project will test whether taking tart cherry concentrate plus fish oil for 12 weeks reduces joint pain and stiffness in women with breast cancer who are taking aromatase inhibitors.

  Recruiting Early Phase 1 Cedars-Sinai Medical Center · Los Angeles, California and 1 other locations · NCT06123286

• Upfront treatment for breast cancer with nodal metastases

  This study is testing if starting treatment with surgery and targeted therapy can help women with early-stage breast cancer that has spread to their lymph nodes live longer and have fewer recurrences.

  Recruiting at 3 sites Phase 2 Cedars-Sinai Medical Center · Los Angeles, California and 2 other locations · NCT06092892

• Exercise program to manage kyphosis

  This study tests whether a stretching exercise program can help kids and teens with kyphosis feel better and improve their posture.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06082739

• Enhancing communication and support for families of critically ill patients

  This study is testing a new program to see if it can help families of critically ill patients in the ICU communicate better and feel more supported during a tough time.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT06039501

• Using a digital platform for home shoulder rehabilitation programs

  This study tests if using a digital platform can help adults with shoulder problems stick to their home exercise programs and reduce the need for in-person therapy visits.

  Recruiting at 2 sites Cedars-Sinai Medical Center · Los Angeles, California and 1 other locations · NCT06016257

• Using NLP feedback to enhance communication in prostate cancer consultations

  This study is testing whether a new feedback system using technology can help improve communication during doctor visits for men who have just been diagnosed with prostate cancer.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT05923684

• Combining stem cell collection with CAR T-cell therapy for blood cancers

  This study is testing if collecting stem cells from patients with blood cancers can safely be combined with CAR T-cell therapy to improve treatment outcomes.

  Recruiting Phase 1 Cedars-Sinai Medical Center · Los Angeles, California · NCT05887167

• Using cyclophosphamide for older patients after stem cell transplant

  This study is testing the best dose of cyclophosphamide for older patients receiving a specific type of stem cell transplant to see how it affects their recovery and health.

  Recruiting Phase 1 Cedars-Sinai Medical Center · Los Angeles, California · NCT05849207

• Treatment for trigger finger using a night orthosis after cortisone injection

  This study tests if wearing a special night splint after a cortisone shot can help people with trigger finger feel better and use their hands more easily.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California and 1 other locations · NCT05837286

• Using a fasting-mimicking diet to improve prostate cancer control and metabolic health

  This study is testing if a special fasting-mimicking diet can help men with advanced prostate cancer feel better and improve their overall health while they receive standard treatment.

  Recruiting at 3 sites Phase 2 Cedars-Sinai Medical Center · Duarte, California and 2 other locations · NCT05832086

• Using simvastatin to improve outcomes in patients with chronic pancreatitis

  This study is testing if simvastatin can help improve the quality of life and slow down disease progression for adults with chronic pancreatitis and recurrent acute pancreatitis.

  Recruiting at 5 sites Early Phase 1 Cedars-Sinai Medical Center · Los Angeles, California and 4 other locations · NCT05771675

• Comparing a Ketogenic Diet to a Standard Anti-Cancer Diet for Glioblastoma Patients

  This study is testing if a Ketogenic Diet can help people with newly diagnosed glioblastoma live longer compared to a standard anti-cancer diet while they receive their usual treatment.

  Recruiting at 4 sites Phase 2 Cedars-Sinai Medical Center · Los Angeles, California and 4 other locations · NCT05708352

• Mapping fat cell types and aging in older adults

  This study is testing how different treatments, like lifestyle changes or a special medication, can improve health and fat cell function in older adults who are obese.

  Recruiting Phase 2/3 Cedars-Sinai Medical Center · Los Angeles, California · NCT05653258

• Combining Bevacizumab with Chemoimmunotherapy for Advanced Lung Cancer with Liver Metastases

  This study is testing whether adding a drug called bevacizumab to a combination of chemotherapy and another treatment can help people with advanced lung cancer that has spread to the liver live longer and feel better.

  Recruiting at 3 sites Phase 2 Cedars-Sinai Medical Center · Los Angeles, California and 2 other locations · NCT05588388

• Combining apalutamide and carotuximab for advanced prostate cancer

  This study is testing if combining two drugs, apalutamide and carotuximab, can help men with advanced prostate cancer who haven't responded to other treatments feel better and live longer.

  Recruiting at 3 sites Phase 2 Cedars-Sinai Medical Center · Duarte, California and 2 other locations · NCT05534646

• Boosting immunotherapy response in high-risk triple-negative breast cancer with CSF-1R blockade and radiation

  This will try pembrolizumab with axatilimab and radiation before surgery to see if it increases complete tumor disappearance in adults with high-risk triple-negative breast cancer.

  Recruiting Phase 2 Cedars-Sinai Medical Center · Los Angeles, California · NCT05491226

• Combining osimertinib and carotuximab for advanced lung cancer treatment

  This study is testing a new combination of two drugs, osimertinib and carotuximab, to see if it can safely help people with advanced lung cancer caused by specific genetic changes.

  Recruiting at 5 sites Phase 1 Cedars-Sinai Medical Center · Beverly Hills, California and 4 other locations · NCT05401110

• Combining Ivermectin with Balstilimab for Advanced Triple Negative Breast Cancer

  This study is testing whether combining ivermectin with balstilimab or pembrolizumab can help people with advanced triple negative breast cancer by shrinking tumors and improving their quality of life.

  Recruiting Phase 1/2 Cedars-Sinai Medical Center · Los Angeles, California · NCT05318469

• New nasal spray delivery system for treating Eustachian tube dysfunction

  This study tests a new nasal spray to see if it can help people with Eustachian tube dysfunction feel better by delivering medication more effectively.

  Recruiting at 4 sites Phase 2 Cedars-Sinai Medical Center · Los Angeles, California and 3 other locations · NCT05275686

• Investigating risk factors for disability progression in Multiple Sclerosis

  This study is trying to find out what factors might make disability get worse in people with Multiple Sclerosis by looking at their medical history and MRI scans.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT05204459

• AI-guided echocardiogram screening for cardiac amyloidosis

  This study is testing whether an AI tool can help doctors find people at high risk for cardiac amyloidosis by analyzing heart ultrasound images more accurately.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT05139797

• Comparing pain management techniques for transgender patients undergoing gender-affirming surgeries

  This study is testing different ways to manage pain for transgender patients having gender-affirming surgeries to see which method works best for them.

  Recruiting Phase 3 Cedars-Sinai Medical Center · Los Angeles, California · NCT04979338

• Pembrolizumab with focused stereotactic radiation before surgery for recurrent glioblastoma

  This trial will test whether giving pembrolizumab plus focused radiation before planned surgery is safe and helps adults with recurrent glioblastoma live longer.

  Recruiting Phase 1/2 Cedars-Sinai Medical Center · Los Angeles, California · NCT04977375

• Using virtual reality to help manage pain in GI cancer patients

  This study is testing if virtual reality can help people with GI cancer manage their severe abdominal pain better than standard treatments.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT04907643

• Using advanced MRI and AI to find early signs of cancer in children with Neurofibromatosis Type 1

  This study is trying to see if advanced MRI scans and artificial intelligence can help find early signs of cancer in children with Neurofibromatosis Type 1.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT04763109

• A test to predict response to bladder cancer treatment

  This study is testing a new urine test to see if it can help predict which bladder cancer patients will benefit from a specific treatment called BCG therapy.

  Recruiting at 6 sites Cedars-Sinai Medical Center · Los Angeles, California and 5 other locations · NCT04564781

• Using gold markers and advanced MRI to improve bladder cancer treatment

  This study is testing if tiny gold markers and a new type of MRI can help doctors better target and treat bladder cancer while preserving the bladder.

  Recruiting at 3 sites Cedars-Sinai Medical Center · Los Angeles, California and 2 other locations · NCT04442724

• Testing a new catheter for better fluid collection during endoscopy

  This study is testing a new type of catheter to see if it can collect fluid from the small intestine more effectively during endoscopy for patients undergoing the procedure.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT04418258

• High dose immunoablation followed by stem cell transplantation for Crohn's disease

  This study is testing whether a high dose of immune treatment followed by a stem cell transplant can help people with severe Crohn's disease who haven't found relief from regular treatments.

  Recruiting Phase 1/2 Cedars-Sinai Medical Center · Los Angeles, California · NCT04224558

• Registry and analysis of Takotsubo Cardiomyopathy patients

  This study is collecting information from people with Takotsubo Cardiomyopathy to see how the condition affects them and to help find better ways to treat it.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT03910569

• Examining small vessel disease in women with heart issues

  This study is trying to see how small blood vessel problems in the heart affect women with heart issues who don't have blocked arteries, to help understand heart failure better.

  Recruiting at 2 sites Cedars-Sinai Medical Center · Los Angeles, California and 1 other locations · NCT03876223

• Evaluating outcomes of transcatheter aortic valve replacement in patients with bicuspid aortic valves

  This study is testing how well transcatheter aortic valve replacement works for people with severe aortic stenosis caused by a bicuspid aortic valve.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT03836521

• New MRI technique for evaluating coronary atherosclerosis

  This study is testing a new MRI method to see if it can better and faster help doctors check for heart artery problems in healthy people and those who might have heart disease.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT03504956

• New urine test for detecting bladder cancer in patients with blood in urine

  This study is testing a new urine test to see if it can better detect bladder cancer in people who have blood in their urine.

  Recruiting at 8 sites Cedars-Sinai Medical Center · Long Beach, California and 7 other locations · NCT03193541

• New urine test for monitoring bladder cancer patients

  This study is testing a new urine test to see if it can better detect recurring bladder cancer in patients, so they might avoid more invasive procedures.

  Recruiting at 2 sites Cedars-Sinai Medical Center · Los Angeles, California and 3 other locations · NCT03193515

• Repository of samples for cerebrovascular disorders

  This study is collecting blood, fluid, and tissue samples from people with cerebrovascular diseases and strokes to help researchers learn more about these conditions and how to improve treatment.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT02910180

• Monitoring small thyroid cancers without immediate surgery

  This study tests whether watching small thyroid cancers closely instead of doing surgery right away is a safe option for patients and looks at how this choice affects their quality of life and anxiety.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT02609685

• Investigating heart function and blood markers in women with coronary dysfunction

  This study is testing how heart function and certain blood markers are related in women with coronary issues and men, to help understand heart failure better.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT02582021

• Evaluating and treating blood clots in heart valve replacements

  This study is testing if advanced imaging can help find and treat blood clots in patients with bioprosthetic aortic valves to improve their health after surgery.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT02318342

• Effects of unrestricted exercise after mid-urethral sling surgery for urinary incontinence

  This study tests if letting women exercise normally right after mid-urethral sling surgery for urinary incontinence helps them recover better and feel happier in the long run compared to sticking to activity restrictions.

  Recruiting Cedars-Sinai Medical Center · Beverly Hills, California · NCT02316275

• New stress testing protocol to study heart issues in women with chest pain

  This study is testing a new way to understand heart problems in women with chest pain but no blocked arteries, to see how their heart functions during stress.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT02301663

• Observing predictors of pituitary tumor recurrence

  This study looks at what factors might cause pituitary tumors to come back or stay active in patients who have had these tumors.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT00599092

• Using cardiac MRI to study healthy women for heart disease insights

  This study is testing how cardiac MRI can help us learn more about heart health in healthy women to improve diagnosis and treatment for women with small artery heart disease.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT00573339

• Investigating Heart Disease in Small Arteries in Men and Women

  This study is testing new ways to diagnose heart disease in small arteries, especially in women with chest pain who don't have major blockages, to help improve their treatment options.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT00573027

NIH-funded research (newest 40 of 410)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Lipid signals that control acetyl-CoA and fat metabolism in NAFLD

  A study exploring how membrane lipids influence acetyl-CoA metabolism to understand and potentially treat nonalcoholic fatty liver disease (NAFLD).

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11591466

• Them1’s role in fat metabolism and MASLD progression

  Aims to understand how a fat-regulating protein (Them1) affects energy use in fat and liver, and how this could contribute to MASLD in people who are overweight.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11591395

• Biomarker-guided Immunosuppression in Kidney Transplant Patients

  A multicenter study in kidney transplant recipients is testing whether a biomarker score from HLA-DR/DQ can guide changes in immunosuppression to reduce rejection risk and drug toxicity.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11550940

• Alpha5 integrin's role in ALS: how a cell switch worsens disease

  Aims to understand how a specific protein called alpha5 integrin in immune cells affects ALS progression and whether blocking it can help extend life.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11540166

• Chlamydia pneumoniae infection and Alzheimer's disease progression

  This project looks at whether a common lung infection, Chlamydia pneumoniae, might influence Alzheimer's disease in people and what that could mean for treatment.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11538116

• Them1 Inhibitors to Help Treat Fatty Liver Disease

  Aims to develop and test small molecule drugs that block Them1 to help people with non-alcoholic fatty liver disease (NAFLD).

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11519341

• Healthy Brain and Child Development study consortium

  A large U.S. study follows thousands of mothers and children from birth to age 10 to understand how genes and environments shape brain development.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11518962

• Understanding a highly flexible cell state in lung cancer that worsens outcomes

  A doctor-scientist at Cedars-Sinai wants to learn how a highly adaptable lung cancer cell state drives disease progression and resistance to therapy, using models that resemble human tumors.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11505050

• PTPRS and lupus nephritis: a new target to reduce kidney damage in lupus

  Aims to understand how PTPRS contributes to kidney inflammation and scarring in lupus nephritis and explore targeting it to help patients.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11465789

• Maternal and child time use and health in families with young children

  A long-term study in mother–child pairs looks at how daily time use (eating, activity, and sleep) affects weight and health for both moms and their very young children.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11464604

• Role of the body's natural cannabis-like system in diabetes progression and heart risk

  This grant studies how the body's endocannabinoid system affects the progression from obesity to diabetes and the associated risk for cardiovascular disease in adults.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11451041

• Federated learning to improve genetic risk prediction for Alzheimer's disease and related dementias

  A new project uses privacy-preserving AI to tailor genetic risk scores for Alzheimer's and related dementias to diverse groups, helping with early planning and care decisions.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11450878

• p53 acetylation and alveolar stem cell aging in progressive lung fibrosis

  Scientists are studying how changes to a cancer-related protein, p53, affect aging lung cells and contribute to a scary lung disease called IPF.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11449164

• EDAS Revascularization for Symptomatic Intracranial Atherosclerotic Disease (Phase IIb)

  A multicenter phase IIb clinical trial tests a surgical bypass option called EDAS to reduce stroke risk in people with symptomatic intracranial atherosclerotic disease.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11439959

• Advancing Ex Vivo Gene Therapy for ASAH1-Related SMA-PME

  A one-time patient-friendly gene therapy approach uses a patient's own stem cells engineered to produce more acid ceramidase to help a rare neurodegenerative condition in affected adolescents.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11436160

• Barber and Pharmacist Team Up to Lower Blood Pressure

  A community-based program where barbershops partner with pharmacists to help Black men lower their blood pressure in Los Angeles.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11419723

• MicroRNAs and corneal healing in healthy and diseased tissues

  A patient-focused study explores how tiny genetic regulators called microRNAs control corneal healing and how this might affect people with corneal diseases.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11418884

• Diabetic cornea: new ways to restore healing and comfort

  Researchers are testing new gene and nano therapies to help the cornea heal better in adults with diabetes.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11418873

• Translational Geroscience Network to Accelerate Aging-Based Therapies

  A nationwide effort aims to speed up testing of aging-focused lifestyle, nutritional, and drug strategies to prevent or treat age-related diseases in adults.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11417303

• AI-Enhanced Virtual Reality CBT to Reduce Anxiety for IBD Patients

  A home-based VR and AI-powered cognitive behavioral therapy program is being tested to help people with inflammatory bowel disease feel less anxious and improve their quality of life.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11415875

• Cardioprotective Y RNA signals in heart macrophages

  A scientist team at Cedars-Sinai is studying how a small RNA from heart-supporting cells might boost the heart’s healing after a heart attack by changing macrophage behavior.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11415116

• Gut bacteria and permeability linked to Kawasaki disease in kids

  A pediatric-focused study exploring how the gut microbiome and intestinal barrier may influence Kawasaki disease and its inflammation.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11414974

• Early detection of pancreatic cancer with an AI analysis of CT scans

  Aims to use an artificial intelligence model to find very small pancreatic tumors on abdominal CT scans to help catch pancreatic cancer earlier.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11414895

• Using AI to find hidden metabolic pathways that affect diseases

  This project builds AI tools to link proteins and small molecules so researchers can uncover metabolic pathways that matter for cancers, diabetes, and other diseases.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11414811

• Role of Prohibitin 1 in alcohol-related colorectal liver metastasis

  This grant studies how a protein called PHB1 in liver cells affects cancer spread to the liver in people who drink alcohol.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11413772

• Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai

  This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11413637

• Biostatistics & Bioinformatics Core for a SCORE on Sex Differences in Microvascular Aging

  A Biostatistics and Bioinformatics Core will support high-quality analysis and data management for a center studying how aging affects small blood vessels and sex differences in heart, brain, and frailty.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411404

• Advanced Imaging Core supports brain, heart and aging research in women

  A specialized core provides advanced brain and body imaging to study how aging and inflammation affect microvasculature and dementia risk in women.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411396

• Career Enhancement Core to boost early-career scientists studying sex differences in aging health

  A program to help early-career researchers develop and lead translational work on how sex differences affect aging-related health outcomes.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411386

• Leadership Administrative Core supports a multi-institution aging and sex-differences research consortium

  This grant backs a leadership and coordination core to help a multi-institution study on microvascular aging and sex differences in heart, brain, and frailty, with education and advocacy components.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411375

• Frailty and sarcopenia in aging adults

  Aging adults, especially women, may develop frailty and muscle loss, and this project explores how muscle blood flow and inflammation relate to these conditions and to dementia and heart problems.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411368

• Coronary microvascular disease, brain aging, and memory in women

  A study at Cedars-Sinai will explore how small blood vessel problems in the heart and brain relate to cognitive decline and dementia in midlife women.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411357

• CMD and HFpEF: Understanding why heart microvessels fail in women

  A study at Cedars-Sinai will look at why tiny heart blood vessels don’t work well in some people with chest symptoms but no blocked arteries, especially in women, and how this relates to heart failure with preserved ejection fraction.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411349

• MAE-WEST HBF: Understanding microvascular aging in aging women and its link to heart, brain, and frailty

  A large cancer-agnostic grant aims to understand how aging-related tiny blood vessel problems and iron buildup in women affect heart health, brain health, cognition, and frailty.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11411307

• Intensive cholesterol-lowering and immune effects in prostate cancer

  A study to see if lowering cholesterol with statins can slow prostate cancer and boost the body’s immune response to the cancer.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11408547

• Biomarker-guided changes in kidney transplant immunosuppression

  This project tests whether a biomarker score from donor and recipient immune markers can guide safer, personalized immunosuppression after kidney transplant.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11406938

• Measuring heart iron with a new MRI method in heart attack patients

  A new MRI method called Quantitative Susceptibility Mapping (QSM) would be tested to accurately measure iron buildup in the heart after a heart attack, which may affect recovery.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11406279

• Biological treatment to reduce ventricular arrhythmias in a pig model of heart disease

  Aims to test if delivering heart-cell–derived exosomes into damaged heart tissue can reduce scar and prevent dangerous ventricular rhythms in a porcine model of chronic ischemic cardiomyopathy.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11402761

• Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer

  A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11401819

• Push-Button MRI to measure heart energy use in heart failure

  A noninvasive MRI method is being developed to measure how much energy the heart uses in people with heart failure.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11401079

Quick answers

How many clinical trials run by Cedars-Sinai Medical Center are recruiting right now?

78, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (78 trials), Japan (3 trials), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 16, Early Phase 1: 4, Phase 1/2: 3, Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →