NIH-funded research U01 cooperative agreement

Healthy Brain and Child Development study consortium

Official title: 1/24 Healthy Brain and Child Development National Consortium

Funded at Cedars-Sinai Medical Center · NIH-11518962 · Data updated 2026-11-12

A large U.S. study follows thousands of mothers and children from birth to age 10 to understand how genes and environments shape brain development.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startSeptember 30, 2021
Project endJune 30, 2027
Funding year2026
Award (this year)$1,603,214
NIH project number4U01DA055366-06
Project IDNIH-11518962 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include pregnant people and their infants enrolled across 27 sites in the U.S. who are willing to participate in long-term assessments and provide biospecimens.

Less likely to help

Participants who do not fit the 0-11 year age range or who choose not to participate in follow-up visits or biospecimen collection may not benefit.

What this research studies

This project brings together many sites to collect brain imaging, behavior, and biological samples from 7,200 mothers and infants, with a harmonized protocol to map developmental trajectories. It focuses on how prenatal and early-life exposures—like maternal health, stress, and substances—affect neurodevelopment. Families would contribute data over time through imaging sessions, assessments, and biospecimen donation, with procedures designed to be standardized across sites. The goal is to build a big, shared resource that researchers can use to improve care for children as they grow.

Why it matters

Potential benefit: If successful, the study could lead to earlier identification of developmental risks and inform interventions to support healthy brain development in children.

How similar studies have gone: Prior neurodevelopmental studies have shown the value of harmonized data across sites for understanding brain development, though this specific large-consortium effort is expansive and innovative.

Where this research is happening

  • Cedars-Sinai Medical Center
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Gao, Wei — Cedars-Sinai Medical Center
  • Study coordinator: Gao, Wei

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.