NIH-funded research R01 grant

Early detection of pancreatic cancer with an AI analysis of CT scans

Official title: Accurate Detection of Early-Stage Pancreatic Tumors using Artificial Intelligence Analysis of Abdominal Computed Tomography Scans

Funded at Cedars-Sinai Medical Center · NIH-11414895 · Data updated 2026-11-12

Aims to use an artificial intelligence model to find very small pancreatic tumors on abdominal CT scans to help catch pancreatic cancer earlier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startSeptember 12, 2025
Project endAugust 31, 2029
Funding year2026
Award (this year)$519,520
NIH project number5R01CA304543-02
Project IDNIH-11414895 on NIH RePORTER

Who could benefit from this research

Could help

Patients with suspected or confirmed pancreatic tumors, or those undergoing abdominal CT scans for evaluation of abdominal symptoms.

Less likely to help

Individuals without pancreatic disease or without access to CT imaging for pancreatic assessment are unlikely to benefit.

What this research studies

This project will develop an AI-based model that analyzes abdominal CT images to detect early-stage pancreatic tumors, focusing on small lesions and regional pancreatic anatomy. It will combine tumor texture in different pancreatic subregions, morphological features of the pancreas and surrounding fat, liver changes, and non-imaging factors to improve detection. The study leverages existing CT data to train and validate the model and will assess performance across tumor sizes and locations to support earlier diagnosis.

Why it matters

Potential benefit: If successful, the AI tool could enable earlier intervention for pancreatic cancer, potentially improving survival chances.

How similar studies have gone: Prior research shows AI can assist radiologists in tumor detection on CT, but early-stage PDAC remains challenging and this approach is promising but still under validation.

Where this research is happening

  • Cedars-Sinai Medical Center
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Qureshi, Touseef Ahmad — Cedars-Sinai Medical Center
  • Study coordinator: Qureshi, Touseef Ahmad

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.