Choosing AVOID or RESIST to help weight management
Official title: CHOICE to AVOID or RESIST: Evaluating Participants' Choice of Self-regulatory Strategy on Weight Management Outcomes: A Pilot Study.
Run by Cedars-Sinai Medical Center · NCT06521021 · Data updated 2026-11-12
Participants will test whether choosing a self-regulatory strategy (AVOID or RESIST) leads to better adherence to a weight-management program for overweight and obese adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Cedars-Sinai Medical Center Academic / other |
| Locations | 1 site (Beverly Hills, California) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | July 1, 2027 |
| Study ends | July 1, 2027 |
| Registry record updated | September 22, 2026 |
| Trial ID | NCT06521021 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18+ with BMI 25-45 kg/m2, English-reading/writing proficiency, and no contraindications to weight loss interventions.
✕Probably not a fit
Individuals not seeking to engage with a self-regulatory strategy or those with contraindications to weight-management programs may see no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares participants who choose a self-regulatory strategy (AVOID or RESIST) with those randomized to a strategy in the parent AVOID-RESIST program, all within the WW digital weight-management platform for 6 months. The goal is to see if active choice improves adherence, retention, and engagement. Adults with BMI 25-45 kg/m2, who speak English and can complete study assessments, will participate; lead site is Cedars-Sinai with collaboration from UC Riverside, Northeastern University, and WW. Participants will be assigned to one of four arms in the randomized group and CHOICE participants will select their preferred strategy to support behavior change per WW recommendations.
Why it matters
Potential benefit: If successful, allowing participants to choose a strategy may improve adherence and weight-management outcomes.
How similar studies have gone: Prior similar approaches have shown mixed results; this design is testing a novel element of active choice within a structured program.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * BMI between 25-45 kg/m2 * Read, write, and speak English with acceptable visual acuity Exclusion Criteria: * Currently enrolled in weight loss interventions or undergoing bariatric surgery * Pregnant women * Individuals for whom weight loss may be contraindicated (e.g., unstable coronary artery disease, end-stage disease, active cancer treatment, uncontrolled insulin-dependent diabetes, portal hypertension, drug/alcohol abuse) * Individuals who have pacemakers or other electronic medical device implantations * Individuals with severe cognitive delays or visual/hearing impairment * Individuals who are unable or unwilling to complete the study assessments / measurements * Individuals currently subscribed to a meal delivery service who are unwilling to pause their subscription for the duration of the study
Where it's running
-
Cedars-Sinai Medical Center
Beverly Hills, California, United States Recruiting
Study contacts
- Principal investigator: Sarah Salvy, PhD — Cedars-Sinai Medical Center
- Study coordinator: Julissa Ruiz, BS
- Email: julissa.ruiz@cshs.org
- Phone: (310) 602-4169
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.