Evaluating and treating blood clots in heart valve replacements

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses the structural and functional integrity of bioprosthetic aortic valves using advanced imaging techniques, including cardiac contrast CT and transthoracic echocardiography. Patients who have undergone bioprosthetic valve replacement will be monitored for thrombotic changes, and those with abnormalities will receive anticoagulation therapy. Follow-up imaging will be conducted after three months to evaluate the effectiveness of the treatment. The goal is to confirm the resolution of thrombotic changes and improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Presence of transcatheter or surgical bioprosthetic aortic valve implanted at least 48 hours prior to enrollment
* Age 18 years or older
* Ability to provide informed consent and follow-up with protocol procedures.

Exclusion Criteria:

* Renal insufficiency (creatinine \> 1.5 mg/dL)
* Known allergy to iodinated contrast agents

Where it's running

• Cedars-Sinai Medical Center
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Raj Makkar, MD — Cedars-Sinai Medical Center, Los Angeles, California
• Study coordinator: Tarun Chakravarty, MD
• Email: tarunchakravarty@gmail.com
• Phone: 3104233977

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.