Push-Button MRI to measure heart energy use in heart failure
Official title: Push-Button Cardiac MRI for Non-Invasive Quantification of Myocardial Energy Consumption in Heart Failure
Funded at Cedars-Sinai Medical Center · NIH-11401079 · Data updated 2026-11-12
A noninvasive MRI method is being developed to measure how much energy the heart uses in people with heart failure.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | August 15, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $769,199 |
| NIH project number | 5R01HL165211-05 |
| Project ID | NIH-11401079 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with heart failure or those at risk who could benefit from noninvasive energetics assessment.
✕Less likely to help
Patients without heart failure or those unable to undergo MRI would have limited or no benefit.
What this research studies
This project aims to provide a simple MRI-based way to quantify the heart’s energy consumption without invasive procedures. By focusing on energy use rather than only structural changes, it seeks to reveal early signs of heart trouble and guide new therapies. The study will translate noninvasive measurements into actionable information that could help tailor treatment for heart failure patients. If successful, clinicians could monitor energetics over time with repeated scans, potentially improving care. Participation would involve imaging sessions and standard clinical follow-ups.
Why it matters
Potential benefit: If successful, patients with heart failure could receive more precise monitoring of their heart’s energy use, guiding personalized treatment.
How similar studies have gone: Previous methods for noninvasive energetics exist but have not become standard care, making this approach relatively novel.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Yang, Hsin-Jung — Cedars-Sinai Medical Center
- Study coordinator: Yang, Hsin-Jung
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.