Condition

HIV/AIDS clinical trials and research

• 23Clinical trials
• 143NIH research projects
• 8Countries

Newest HIV/AIDS clinical trials

All recruiting trials (23)

• Peer-led Dynamic Choice HIV Prevention for Women

  This trial tests a peer-led HIV prevention approach to see if it helps women at higher risk in Uganda better prevent HIV than standard care.

  Recruiting University of California, San Francisco · Kampala · NCT07787988

• Improving long-term medication adherence for HIV treatment

  This study is testing whether daily text messages and rewards can help people starting HIV treatment stick to their medication plan over the long term.

  Recruiting Rand · Kampala · NCT06949774

• Using a mobile app to reduce HIV infections in young men and non-binary individuals

  This study is testing a mobile app designed to help young men and non-binary individuals reduce their risk of getting HIV.

  Recruiting at 2 sites Columbia University · Chicago, Illinois and 1 other locations · NCT06741631

• Mobile intervention for HIV prevention in young men who have sex with men

  This study is testing a mobile program that helps young men who have sex with men learn about and access HIV prevention methods, like PrEP, to see if it can reduce their risk of getting HIV.

  Recruiting Columbia University · New York, New York · NCT06741618

• A program to improve PrEP use among young women in Kenya

  This study is testing a new program to help young women in Kenya use HIV prevention medication more effectively by providing support and resources tailored to their needs.

  Recruiting Massachusetts General Hospital · Kisumu · NCT06566430

• Using a pill sensor system to improve HIV treatment adherence

  This study is testing a new pill sensor system to see if it helps adults with HIV stick to their treatment better and improve their health.

  Recruiting Phase 2 University of California, Los Angeles · Los Angeles, California · NCT06480578

• Using community health workers and mobile health to improve HIV treatment outcomes

  This study is testing whether using community health workers and mobile health tools can help people with HIV in the Deep South stick to their treatment and improve their health outcomes.

  Recruiting at 5 sites Columbia University · Hobson City, Alabama and 4 other locations · NCT06472206

• Improving care for HIV patients by addressing structural racism and discrimination

  This study is trying to see if changing the way clinics treat patients can improve HIV care for racial and ethnic minorities who are facing discrimination.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT06462807

• Economic and relationship support to reduce alcohol use in Malawi

  This study is testing whether a program that helps couples in Malawi save money and learn relationship skills can reduce heavy drinking among people living with HIV.

  Recruiting University of California, San Francisco · Zomba · NCT06367348

• Improving HIV care engagement for Latinos

  This study is testing a new program called ADELANTE to see if it helps Latinos with HIV better manage their health and achieve lower viral levels compared to just getting reminder phone calls.

  Recruiting at 2 sites Massachusetts General Hospital · Miami, Florida and 1 other locations · NCT06274632

• Evaluating on-demand HIV prevention in men who have sex with men in Thailand and France

  This study is testing a new on-demand HIV prevention method for men who have sex with men in Thailand and France to see if it works better than the current standard treatment.

  Recruiting at 6 sites Phase 3 ANRS, Emerging Infectious Diseases · Paris and 5 other locations · NCT05813964

• A mobile game to help young people stick to their HIV prevention medication

  This study tests a mobile game called Viral Combat to see if it helps young people aged 15-34 stick to their HIV prevention medication better than a different game.

  Recruiting at 3 sites Rhode Island Hospital · Boston, Massachusetts and 2 other locations · NCT05762705

• Web-based support for women living with HIV/AIDS

  This study is testing a new online support program to see if it can help women living with HIV/AIDS who have faced violence stick to their medication and improve their health.

  Recruiting University of California, San Diego · La Jolla, California · NCT05509959

• Assessing liver fat levels in HIV/AIDS patients on different medications

  This study is trying to see how different HIV medications affect liver fat levels in patients living with HIV/AIDS to understand the risk of liver disease.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT05330923

• Investigating lung microbiome and immune responses in tuberculosis patients

  This study looks at the lung bacteria and immune responses in people with active tuberculosis to see how they change before and after treatment.

  Recruiting at 3 sites University of Stellenbosch · Cape Town, Western Cape and 2 other locations · NCT04700579

• Monitoring pregnancy and newborn outcomes in HIV-positive and HIV-negative women

  This study is trying to see how pregnancy and baby health outcomes differ between women with and without HIV to improve care for both groups.

  Recruiting Indiana University · Eldoret · NCT04405700

• Understanding HIV interactions during treatment interruptions

  This study is testing how HIV behaves in people when they take a break from their treatment to see what might cause the virus to come back.

  Recruiting University of California, San Francisco · San Francisco, California · NCT04359186

• Combination of Dolutegravir and Lamivudine for HIV Treatment

  This study is testing whether a simpler two-drug treatment for HIV can work just as well and be safe for people who have been on a three-drug regimen.

  Recruiting Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT03884673

• Observational research on chronic diseases and healthcare analytics

  This study looks at health records to see how well different treatments work for chronic diseases like HIV and hepatitis, aiming to improve patient care and support.

  Recruiting Epividian · Durham, North Carolina · NCT03813862

• Mobile health intervention to support women with HIV/AIDS

  This study is testing a mobile health program that sends text reminders to women with HIV to help them stick to their treatment plans and improve their health.

  Recruiting University of Miami · Miami, Florida · NCT03738410

• Observing simplified HIV treatment in China

  This study is testing a simpler HIV treatment plan to see if it helps people in China stick to their medication and stay healthy over three years.

  Recruiting Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT03603977

• CAR-T Cell Therapy for HIV Patients

  This study tests if a new CAR-T cell therapy can safely help HIV patients who have their virus under control by boosting their immune system to fight the virus better.

  Recruiting Phase 1 Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT03240328

• Implementing HIV testing in opioid treatment programs

  This study is testing if coaching programs can help people in opioid treatment programs get more HIV and Hepatitis C tests and connect to care.

  Recruiting Columbia University · New York, New York · NCT03135886

NIH-funded research (newest 40 of 143)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya

  A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11625516

• FIOCRUZ HIV/AIDS Clinical Trials Unit: advancing HIV prevention and treatment in Brazil

  A Brazilian clinical trials unit led by Dr. Beatriz Grinsztejn is testing and speeding up new HIV prevention and treatment strategies to help people living with HIV/AIDS and those at risk.

  NIH research Fundacao Oswaldo Cruz · Rio de Janeiro, BRAZIL · NIH-11601065

• Breeding colony expansion to support HIV/AIDS research with rhesus macaques

  A funding opportunity to expand a specialized Rhesus macaque breeding population to support HIV/AIDS research at Tulane’s primate facility.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11581742

• HIV Resilience Observatory in a rhesus macaque colony expansion

  A program to build a rhesus macaque breeding colony and use AI-powered monitoring to study why some HIV/AIDS outcomes differ among individuals with similar backgrounds.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11581712

• Indoor-Outdoor Housing Expansion to Support HIV/AIDS-Related Research

  A HIV-focused project at a primate research center will use new indoor/outdoor housing and AI-assisted monitoring to study why people with similar backgrounds can have very different HIV outcomes.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11581704

• Hearing changes in people with HIV and in people without HIV in Tanzania

  This project follows people living with HIV and similar individuals in Tanzania to see how hearing and brain function relate over time and whether hearing tests can help predict cognitive changes.

  NIH research Dartmouth College · Hanover, United States · NIH-11575474

• Bridging clinic and community care for HIV-positive women facing abuse

  A program will adapt and use an evidence-based approach called CUES to help women living with HIV who experience intimate partner violence get better HIV and mental health outcomes by coordinating care with community organizations.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11563817

• Columbia HIV/AIDS Clinical Trials Unit focuses on advancing prevention and treatment in NYC

  A patient-facing CTU in NYC coordinates clinical trials to improve HIV prevention and care for people living with HIV and those at risk.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11540397

• Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related Meningitis

  A study in Uganda aims to use faster, better tests and a new antifungal to help people with HIV who develop meningitis.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11539368

• Ending Tobacco Use with a Smartphone Program for Cambodian People Living with HIV/AIDS

  A smartphone-based quit-smoking program designed for people living with HIV/AIDS in Cambodia to help reduce tobacco use alongside HIV treatment.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11535291

• Adolescent HIV Care: Weight Loss Pill + Digital Counseling Trial

  A youth-focused trial tests whether adding a weekly semaglutide weight-loss medicine to tailored digital lifestyle coaching helps overweight teens and young adults living with HIV improve weight and heart health.

  NIH research Florida State University · Tallahassee, United States · NIH-11530515

• Combined motivational interviewing with real-time prompts to cut risky drinking in young adults at high HIV risk

  A 3-arm study tests whether remote motivational interviewing alone or with real-time GPS-triggered messages can help 18+-year-olds at high HIV risk drink less and reduce risky behaviors.

  NIH research Yale University · New Haven, United States · NIH-11482052

• Improving accuracy of HIV research that uses medical records

  This work creates ways to combine routine electronic health records with smaller, carefully checked samples to give more accurate results for people living with HIV.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11469944

• Improving accuracy of HIV medical records

  This project combines routine electronic health records with carefully checked medical record samples to make research about people living with HIV more accurate.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11469943

• Fixing linked errors in HIV patient records to improve research

  This project develops new ways to combine routine medical records with verified samples to make research about people living with HIV more accurate.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11469942

• Better ways to check and use medical-record data for people with HIV

  This project creates methods to combine routine medical records with carefully checked samples so HIV research gives more accurate answers for people living with HIV.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11469941

• Pediatric HIV Aging and Reproductive Health: Understanding Allostatic Load in PHIV and Pregnant PWH

  This grant studies how long-term HIV and aging affect reproductive health and pregnancy outcomes in people with perinatal or pediatric HIV, using real-world data and biospecimens.

  NIH research Harvard University D/b/a Harvard School of Public Health · Boston, United States · NIH-11416786

• Alcohol and HIV/AIDS: Understanding how drinking affects HIV health and aging

  A large, ongoing program studies how alcohol use impacts HIV or age-related health issues in people living with HIV and in similar comparisons.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11416361

• Ending Tobacco Use with a smartphone program for Cambodians living with HIV

  A smartphone-based, tailored smoking-cessation program for people living with HIV in Cambodia is being tested to help them quit smoking.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11413458

• Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-Related Meningitis

  This project tests faster, better ways to diagnose HIV-related meningitis and improve brain health in adults in Africa.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11406140

• How alcohol affects TB risk and lung health in people living with HIV

  This program looks at how drinking alcohol changes the chance of getting TB, developing TB after preventive therapy, and long-term lung problems for people living with HIV.

  NIH research Boston Medical Center · Boston, United States · NIH-11405066

• Operations and Collaborations Center for Adolescent HIV Trials Network (ATN)

  A center in charge of coordinating operations, training, and collaborations to support adolescent HIV/AIDS research across ATN sites.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402845

• Adolescent HIV Care and Research Collaboration Center

  A consortium in southwest Florida will engage and follow adolescents and young adults at risk for or living with HIV to improve their prevention and treatment through established community and clinical partnerships.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402844

• Adolescent HIV Care and Research Network Operations Center

  A national network helps improve care and research for adolescents at risk for or living with HIV by coordinating sites, community voices, and ethical research planning.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402843

• ATN Operations and Collaborations Center for HIV/AIDS Interventions in adolescence and young adults

  A national network at St. Jude and partners is planning youth-focused HIV prevention and treatment trials to help adolescents and young adults who are at risk or living with HIV.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402841

• AYA HIV care and prevention improvements across the Johns Hopkins ATN collaboration

  A patient-facing program will help youth ages 13-24 with HIV get better access to care, stay in treatment, and reduce transmission through coordinated research and clinical care efforts.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402840

• Adolescent HIV/AIDS Trial Network Operations and Collaborations Center at Fenway Health

  A center based in Boston will coordinate and support adolescent HIV trials to improve care, prevent HIV spread, and keep youth enrolled in important studies.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402838

• Adolescent HIV Prevention and Care Network Operations Center

  A national network-based effort led by ATN and AYAR to improve HIV prevention and care for teens and young adults at high risk in urban communities.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402835

• Adolescent and young adult HIV prevention and care partners across CNH network

  This grant supports a national network to improve HIV prevention and care for youths and young adults living with or at risk for HIV.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402834

• Adolescent HIV Care Network Operations Center for ATN in Los Angeles

  A national HIV research network is partnering with Los Angeles communities to coordinate and run adolescent and young adult HIV studies to improve prevention, care, and outcomes.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402833

• Site network to advance HIV prevention and care for adolescents and young adults in Houston

  A nationwide-adolescent HIV trial network is partnering with a Houston site to test and implement new ways to prevent HIV and improve care for teens and young adults living with or at risk for HIV.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402832

• Adolescent HIV Network Operations and Collaborations Center

  A national program to keep HIV-focused research for teens and young adults running smoothly, by coordinating partners, logistics, and study protocols.

  NIH research Westat, INC. · Bethesda, UNITED STATES · NIH-11402831

• Tailored smartphone messages to help Cambodians with HIV quit smoking

  A smartphone program that sends personalized messages and offers medications to help adults living with HIV in Cambodia stop smoking.

  NIH research H. Lee Moffitt Cancer Ctr & Res Inst · Tampa, United States · NIH-11401633

• Tracking how Cryptococcus yeast changes in HIV/AIDS patients

  A study to understand why Cryptococcus neoformans behaves differently in people with HIV/AIDS and how this affects disease severity and treatment.

  NIH research Duke University · Durham, United States · NIH-11392442

• Hearing and brain function in people with HIV in Tanzania

  This project studies how hearing and brain function change over time in people with HIV and similar people without HIV in Tanzania, to see if ear tests can foretell cognitive decline.

  NIH research Dartmouth College · Hanover, United States · NIH-11389566

• Dissemination of Point-of-Care HIV/AIDS Diagnostics in Resource-Limited Settings

  A national center in HIV/AIDS diagnostics aims to speed up practical, real-world testing by sharing know-how and fostering partnerships to bring better point-of-care tests to people living with HIV in low-resource settings.

  NIH research Northwestern University · Chicago, United States · NIH-11385937

• Point-of-care HIV/AIDS and emerging infections diagnostics center

  A U54 grant to Northwestern University is advancing quick, home-based and clinic-friendly diagnostic tools for HIV, AIDS-related illnesses, and other emerging infections, with a focus on low-resource settings and people living with HIV in the U.S. and globally.

  NIH research Northwestern University · Chicago, United States · NIH-11385930

• Technology Center for Patient-Friendly Point-of-C care HIV/AIDS Diagnostics

  A Northwestern center is funding and improving easy-to-use HIV/AIDS diagnostic tools that work in low-resource settings and help people living with HIV in the U.S.

  NIH research Northwestern University · Chicago, United States · NIH-11385926

• Center for Innovation in Point-of-Care HIV/AIDS Diagnostics at Northwestern

  A national effort to speed up affordable, rapid HIV/AIDS and other infectious-disease tests that can be used at home or in clinics, especially in low-resource settings, with Northwestern leading the coordination.

  NIH research Northwestern University · Chicago, United States · NIH-11385925

• Better diagnosis and brain health for people with HIV meningitis

  This project tries faster tests and a new oral antifungal to help adults with HIV who develop meningitis.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11383982

Related topics

Quick answers

How many HIV/AIDS clinical trials are recruiting right now?

23, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (12 trials), China (4 trials), Uganda (2 trials), Kenya (2 trials), South Africa (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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