Clinical trial Recruiting at 2 sites Interventional Ages 16 to 29 Men only

Using a mobile app to reduce HIV infections in young men and non-binary individuals

Official title: MyPEEPS LITE Trial

Run by Columbia University · NCT06741631 · Data updated 2026-11-12

This study is testing a mobile app designed to help young men and non-binary individuals reduce their risk of getting HIV.

Quick facts

Study typeInterventional
Ages16 Years to 29 Years
SexMen only
Enrollment3200 (estimated)
SponsorColumbia University
Academic / other
Locations2 sites (Chicago, Illinois and 1 other locations)
StatusRecruiting
StartedJanuary 10, 2025
Main results expectedDecember 1, 2027
Study endsDecember 1, 2028
Registry record updatedFebruary 27, 2026
Trial IDNCT06741631 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are HIV-negative or status unknown young men and non-binary individuals aged 16-29 who have engaged in anal sex with someone who has a penis in the last year.

Probably not a fit

Patients who identify as transgender will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial aims to recruit a diverse national sample of 2,500 high-risk young men who have sex with men and non-binary individuals aged 16-29 to evaluate the effectiveness of the MyPEEPS Mobile intervention in reducing new HIV infections. The study employs community-informed advertisements and electronic methods for recruitment and retention, comparing the intervention's efficacy against standard care. By integrating robust epidemiological data, the trial seeks to identify factors influencing HIV seroconversion in this vulnerable population, ultimately advancing HIV prevention strategies.

Why it matters

Potential benefit: If successful, this intervention could significantly lower the rates of new HIV infections among high-risk youth.

How similar studies have gone: Other studies have shown success with similar digital health interventions in HIV prevention, indicating a promising approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be between 16-29 years of age;
* Sex assigned at birth is male and identify gender as male or non-binary;
* Understand and read English;
* Live within US and its territories;
* Own or have access to a smartphone;
* Self-report anal sex with someone who has a penis in the last 12 months; and
* Be HIV-negative or status unknown

Exclusion Criteria:

* Individuals who identify as transgender

Where it's running

  • Ann & Robert H. Lurie Children's Hospital of Chicago
    Chicago, Illinois, United States
    Recruiting
  • Columbia University
    New York, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Rebecca Schnall, PhD, MPH — Columbia University
  • Study coordinator: Rebecca Schnall, PhD, MPH
  • Email: rb897@columbia.edu
  • Phone: 212-342-6886

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.